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Ruscogenin

Catalog No. T6S1256 CAS 472-11-7

1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.

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Ruscogenin, CAS 472-11-7

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	430.629
Formula	C27H42O4
CAS No.	472-11-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 78 mg/mL(181.1 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Huang Y L , Kou J P , Ma L , et al. Possible Mechanism of the Anti-inflammatory Activity of Ruscogenin: Role of Intercellular Adhesion Molecule1 and Nuclear Factor-κB[J]. Journal of Pharmacological Sciences, 2008, 108(2):198-205.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library HIF-1 Signaling Pathway Compound Library Traditional Chinese Medicine Monomer Library Anti-Pancreatic Cancer Compound Library Natural Product Library for HTS Anti-Tumor Natural Product Library Immunology/Inflammation Compound Library Anti-Cancer Active Compound Library MAPK Inhibitor Library NF-κB Signaling Compound Library

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Keywords

Ruscogenin 472-11-7 NF-Kb信号通路免疫与炎症 NF-κB NOD-like Receptor (NLR) NOS inhibit Inhibitor inhibitor

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