Powder: -20°C for 3 years
In solvent: -80°C for 2 years
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.
Description | 1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation. |
Molecular Weight | 430.629 |
Formula | C27H42O4 |
CAS No. | 472-11-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 78 mg/mL(181.1 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Ruscogenin 472-11-7 NF-Kb信号通路 免疫与炎症 NF-κB NOD-like Receptor (NLR) NOS inhibit Inhibitor inhibitor