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Ruscogenin

Catalog No. T6S1256 CAS 472-11-7

1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.

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Ruscogenin, CAS 472-11-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 36.00
5 mg	In stock	$ 79.00
10 mg	In stock	$ 117.00
25 mg	In stock	$ 195.00
50 mg	In stock	$ 288.00
100 mg	In stock	$ 433.00
1 mL * 10 mM (in DMSO)	In stock	$ 87.00

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Purity: 99.69%

Purity: 98.12%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Liliaceae > Ophiopogon

Molecular Weight	430.62
Formula	C27H42O4
CAS No.	472-11-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 78 mg/mL(181.1 mM)

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

References and Literature

1. Huang Y L , Kou J P , Ma L , et al. Possible Mechanism of the Anti-inflammatory Activity of Ruscogenin: Role of Intercellular Adhesion Molecule1 and Nuclear Factor-κB[J]. Journal of Pharmacological Sciences, 2008, 108(2):198-205.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Pyroptosis Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library Antioxidant Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Traditional Chinese Medicine Monomer Library Bioactive Compounds Library Max Anti-Aging Compound Library Anti-Fibrosis Compound Library Human Metabolite Library

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Keywords

Ruscogenin 472-11-7 Immunology/Inflammation NF-Κb NF-κB NOS NOD-like Receptor (NLR) inhibit Inhibitor inhibitor

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