Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 55.00 | |
2 mg | In stock | $ 89.00 | |
5 mg | In stock | $ 173.00 | |
10 mg | In stock | $ 258.00 | |
25 mg | In stock | $ 437.00 | |
50 mg | In stock | $ 629.00 | |
100 mg | In stock | $ 888.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 61.00 |
Description | BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release. |
Targets&IC50 | PDE4:3 μM |
Cell Research | Mononuclear cells were incubated for 30 min with BW-A 78U (0.01-10 μM). The cells were then stimulated with lipopolysaccharide (10 μg/mL) overnight at 37°C in an atmosphere of 5% CO2 at 100% humidity. Cell-free supernatants were collected, centrifuged (2000 g), and stored frozen at -20°C before TNF-α determination. TNF-α concentrations in cell culture supernatants were determined by specific ELISA using a commercial kit. The sensitivity of the assay was 1 pg/mL. The absorbance at 450 nm was assessed with an ELISA reader. |
Synonyms | BW-A78U |
Molecular Weight | 257.27 |
Formula | C13H12FN5 |
CAS No. | 101155-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL
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BW-A 78U 101155-02-6 Metabolism PDE inhibit Inhibitor BW A 78U BW-A78U Phosphodiesterase (PDE) BWA 78U inhibitor