Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 72.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 198.00 | |
100 mg | In stock | $ 297.00 | |
500 mg | In stock | $ 733.00 |
Description | Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression. |
Source |
Synonyms | Rubimaillin |
Molecular Weight | 284.31 |
Formula | C17H16O4 |
CAS No. | 55481-88-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL(70.3 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble
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Mollugin 55481-88-4 Angiogenesis Chromatin/Epigenetic JAK/STAT signaling Stem Cells Tyrosine Kinase/Adaptors JAK HER NF-κB c-Myc Nuclear factor-kappaB Inhibitor inhibit Apoptosis HEK293 H22-tumor HepG2 cells Vascular endothelial growth factor receptor VEGFR Reactive Oxygen Species ROS HeLa antitumor Liver cancer Hep3B Myc DNA damage Rubimaillin anti-hepatocellular Nuclear factor-κB inhibitor