Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Crocin suppresses tumor necrosis factor (TNF)alpha-induced apoptosis of pheochromocytoma (PC12) cells by modulating mRNA expressions of Bcl-2 family proteins, which trigger downstream signals culminating in caspase-3 activation followed by cell death. Crocin prevented the activation of nSMase by enhancing the transcription of gamma-glutamylcysteinyl synthase, which contributes to a stable glutathione supply that blocks the activity of nSMase.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 60.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 60.00 |
Description | Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne or tranquilizer. Crocin suppresses tumor necrosis factor (TNF)alpha-induced apoptosis of pheochromocytoma (PC12) cells by modulating mRNA expressions of Bcl-2 family proteins, which trigger downstream signals culminating in caspase-3 activation followed by cell death. Crocin prevented the activation of nSMase by enhancing the transcription of gamma-glutamylcysteinyl synthase, which contributes to a stable glutathione supply that blocks the activity of nSMase. |
Source |
Synonyms | Gardenia Yellow, Alpha-Crocin |
Molecular Weight | 976.96 |
Formula | C44H64O24 |
CAS No. | 42553-65-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.77 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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Crocin 42553-65-1 Others Endogenous Metabolite Crocin I a-Crocin α-Crocin inhibit Inhibitor Gardenia Yellow Alpha-Crocin inhibitor