Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 60.00 | |
5 mg | In stock | $ 147.00 | |
10 mg | In stock | $ 228.00 | |
25 mg | In stock | $ 478.00 | |
50 mg | In stock | $ 689.00 | |
100 mg | In stock | $ 982.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 198.00 |
Description | SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers. |
Targets&IC50 | TNF-α:22 µM |
In vitro | The survivability of aHSCs is significantly rescued by SPD304 dihydrochloride (2 μM). The production of lipid hydroxides and intracellular GSH are increased as well. GA (75 μM) and SPD304 dihydrochloride (2 μM) downregulate TRADD (almost 2-fold) and p−RIP3 (1.4−fold) compared to GA and promote the activation of caspase 8[4]. |
Molecular Weight | 620.53 |
Formula | C32H34Cl2F3N3O2 |
CAS No. | 1049741-03-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.2 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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SPD304 dihydrochloride 1049741-03-8 Apoptosis TNF SPD304 Dihydrochloride SPD304 SPD-304 Dihydrochloride SPD-304 SPD 304 Dihydrochloride SPD 304 SPD-304 dihydrochloride inhibitor inhibit