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Cat No. | Product Name | Synonyms | Targets |
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T5416 | T-5224 | MMP | |
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. | |||
T17073 | Thioflavin T | Basic Yellow 1 | Others |
Thioflavin T (Basic Yellow 1) is a widely used dye for visualizing and is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. | |||
T16967 | T-00127_HEV1 | PI4K | |
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta (IC50: 60 nM). | |||
T4681 | T863 | DGAT-3,DGAT-1 inhibitor | Acyltransferase , Transferase |
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis... | |||
T19822 | RH-5849 | RH 5849,1,2-Dibenzoyl-1-(T-Butyl)Hydrazine,RH5849,1,2-Dibenzoyl-1-Tert-Butylhydrazine | Others |
RH-5849 (1,2-Dibenzoyl-1-Tert-Butylhydrazine) is a novel Insect growth regulator that can be used as a potential insecticide to control olive fruit fly. | |||
T13998 | 1-(t-Boc-Aminooxy)-3-aminooxy-propane | Others | |
1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs[1]. | |||
T9720 | T3Inh-1 | Others | |
T3Inh-1 is an effective and selective inhibitor of ppGalNAc-T3 with an IC50 of 7 µM. T3Inh-1 prevents breast cancer cells. T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic sid... | |||
T6690 | T0901317 | Apoptosis , FXR , Liver X Receptor , ROR | |
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB). | |||
T9616 | PD-1/PD-L1-IN-10 | PD-1/PD-L1 | |
PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy. | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T81054 | T-1-MCPAB | VEGFR | |
T-1-MCPAB, a VEGFR-2 inhibitor with an IC50 of 0.135 µM, effectively suppresses MCF7 cell migration and has applications in cancer research [1]. | |||
T10765 | Eragidomide | CC-90009,Cereblon modulator 1 | Apoptosis , Ligand for E3 Ligase , Molecular Glues |
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex. | |||
TP2401 | Peptide T amide | D-Ala(1)-peptide T amide | |
Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy. | |||
T6255 | Bromosporine | Epigenetic Reader Domain , CDK | |
Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively. | |||
T72548 | IGUANA-1 free base | STL5-T-0057 | |
IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor, demonstrating an IC50 value of 30 nM. It efficaciously inhibits the growth of SW480 cells under both adherent and spheroid conditions, yielding IC5... | |||
T25574 | Ketomycin | Antibiotic R-3,Antibiotic T 86A,Cyclohexenyl-1-glyoxalic acid | |
Ketomycin is an antibiotic agent. It is formed from shikimic acid via chorismic acid and prephenic acid. | |||
T16048 | Methylamino-PEG1-Boc | Methylamino-PEG1-t-butyl ester | Others |
Methylamino-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T13061 | T338C Src-IN-1 | Others | |
T338C Src-IN-1 is a potent mutant-Src T338C inhibitor(T338C,IC50=111 nM relative to WT c-Src (10-fold increase)). | |||
T19556 | SAHA chloroalkane T1 | Others | |
SAHA chloroalkane T1 is a novel compound formed by combining Vorinostat (SAHA) with a chloroalkane capture tag, referred to as T1. This innovative approach involves tethering the SAHA molecule with the T1 tag, resulting ... | |||
T14182 | Alkyne-ethyl-PEG1-Boc | Alkyne-ethyl-PEG1-t-butyl ester | Others |
Alkyne-ethyl-PEG1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sy... | |||
T0370 | Pheniramine maleate | Daneral,Inhiston,Trimetose | 5-HT Receptor , Histamine Receptor |
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... | |||
TNU1443 | 1,4-Anhydro-2-de oxy-3-O-(t-butyldiphenylsilyl-D-erythro-pent-1-enitol | ||
1,4-Anhydro-2-de oxy-3-O-(t-butyldiphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1443 and the CAS number is 130277-32-6. | |||
TNU1642 | 1,4-Anhydro-2-deoxy-3,5-bis-O-(t-butyl diphenylsilyl-D-erythro-pent-1-enitol | ||
1,4-Anhydro-2-deoxy-3,5-bis-O-(t-butyl diphenylsilyl-D-erythro-pent-1-enitol is a useful organic compound for research related to life sciences. The catalog number is TNU1642 and the CAS number is 105930-84-5. | |||
T67259 | Josiphos SL-J009-1 Pd G3 | ||
Josiphos SL-J009-1 Pd G3 has a wide range of applications in life science related research. | |||
T10339 | Antitrypanosomal agent 1 | Parasite | |
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM). | |||
T64320 | ML251 | Glucokinase , Parasite | |
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]... | |||
T28895 | T-0509 | T 0509,T0509 | Adrenergic Receptor |
T-0509 is a selective beta 1 receptor agonist that increases inotropy in canine ventricular muscle and selectively down-regulates rat cardiac beta 1-adrenoceptors. | |||
T76924 | Efalizumab | Hu1124,HU 1124 | Integrin |
Efalizumab, a novel potent regulator of T cells, is a humanized LFA-1 α subunit (CD11a) monoclonal antibody. Efalizumab has inhibitory effects on T cell activation, skin T cell transport, and T cell adhesion to keratinoc... | |||
T10565 | BMS-1001 hydrochloride | PD-1/PD-L1 | |
BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activat... | |||
T38369 | CAY10678 | Prostaglandin Receptor , PD-1/PD-L1 | |
CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS | |||
T4665 | Temsavir | BMS626529 | HIV Protease |
Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. | |||
TP1549L | NY-BR-1 p904 A2 acetate(347142-73-8 free base) | Others | |
T-cell clones specific for this NY-BR-1 p904 A2 acetate(347142-73-8 free base) can recognize breast tumor cells expressing NY-BR-1. | |||
TP1785L | Peptide T acetate(106362-32-7 free base) | Others , HIV Protease | |
Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding... | |||
T3521 | γ-Secretase-IN-1 | Compound E | Beta Amyloid , Gamma-secretase |
γ-Secretase-IN-1 is a potent γ-secretase inhibitor that displays partial antiproliferative activity on T-47D cells and inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage. | |||
T76750 | Cemiplimab | REGN-2810,SAR-439684 | Others |
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance... | |||
T63059 | CRK12-IN-1 | Antibiotic | |
CRK12-IN-1 is a potent CRK12 inhibitor.CRK12-IN-1 has insecticidal activity, with inhibitory effects on Trypanosoma brucei (T.b. brucei) and Trypanosoma congolense (T. congolense) with EC50s of 1.3 and 18 nM, respectivel... | |||
TQ0174 | Mavorixafor | AMD-070 | CXCR |
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC... | |||
T63790 | Cbl-b-IN-3 | E1/E2/E3 Enzyme | |
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n... | |||
T10570 | Fostemsavir Tris | BMS-663068 Tris | HIV Protease |
Fostemsavir Tris (BMS-663068 Tris) is the prodrug of BMS-626529,is a oral, safe and effective inhibitor of HIV-1 attachment. It inhibits human immunodeficiency virus type 1 (HIV-1) infection by binding to gp120 and inter... | |||
T77433 | Feladilimab | GSK3359609 | COX , PD-1/PD-L1 |
Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist. Feladilimab binds to ICOS-expressing T cells, induces IFNγ, and increases PD-1/L1 expression. Feladilimab has anti-tumor activity and can b... | |||
T60077 | SCP1-IN-1 | Others | |
SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-1 promotes REST degradation and reduces transcriptional activity. In some glioblastoma cells, the high level of REST protein... | |||
T24816 | SP-100030 | SP100030,SP 100030 | NF-κB |
SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ... | |||
T8656 | CAY10404 | 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T | Apoptosis , Akt , COX |
CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel... | |||
T36944 | Ara-G | Nucleoside Antimetabolite/Analog | |
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... | |||
T76781 | Itolizumab | EQ-001 | Others |
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti... | |||
T35394 | Sintilimab (anti-PD-1) | IBI308,Sintilimab (anti-PD-1) | PD-1/PD-L1 |
Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i... | |||
T6964 | Resiquimod | R848,S28463 | HCV Protease , TLR |
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti... | |||
T5697 | BMS-1166 | PD-1/PD-L1 | |
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor. | |||
T7123 | AMG-47a | VEGFR , p38 MAPK , JAK , Src | |
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10024 | 1-Octanol | Octanol | Calcium Channel , Endogenous Metabolite |
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ... | |||
T8716 | Physalin F | Apoptosis | |
Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM... | |||
T3S1892 | Crassicauline A | Crassicauline I | Others |
1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively. | |||
T6S1885 | Benzoylmesaconine | Mesaconine 14-benzoate | Others |
Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activi... | |||
T6S0781 | Phellodendrine | Phallodendrin | Others , NF-κB , Akt |
1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. | |||
T37280 | PE(18:1(9Z)/0:0) | Endogenous Metabolite | |
PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ... | |||
TN2244 | Sulfuretin | NF-κB , Autophagy | |
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr... | |||
TQ0131 | Rocaglamide | Rocaglamide A,Roc-A | HSP , NF-κB , PERK |
Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells. | |||
T6S0033 | Crotonoside | Isoguanosine,2-HYDROXYADENOSINE | Others , FLT , HDAC |
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stim... | |||
T2S1792 | Lycobetaine | Ungeremine | Antibacterial |
1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively... | |||
T1257 | Bestatin | Ubenimex | Others , Aminopeptidase , Antibacterial , Antibiotic , LTR |
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin... | |||
T4S0867 | Pogostone | DHELWANGIN | Apoptosis , Antibacterial , Autophagy |
1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire... | |||
TJS1779 | Protosappanin A | PTA | NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT |
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ... | |||
T3824 | Jaceosidin | Apoptosis , BCL , COX , UGT | |
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway... | |||
T3794 | Pentagalloylglucose | Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose | Influenza Virus |
1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten... | |||
T2S0843 | Negletein | 7-O-Methylbaicalein,Baicalein-7-methylether | IL Receptor , TNF , NOS , Interleukin |
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n... | |||
T2S2215 | Crebanine | Apoptosis , Others , Akt | |
1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat... | |||
T78488 | Palmaturbine hydroxide | ||
Palmatine hydroxide, isolated from T. sinensis [1], is a chemical compound. | |||
T82336 | Ganoderic acid T | ||
Ganoderic acid T, a natural compound isolated from Ganoderma lucidum [1], exhibits various pharmacological properties. | |||
T11365 | Ganodermanontriol | Others | |
Ganodermanontriol, a sterol derived from Ganoderma lucidum, showcases hepatoprotective activity and possesses anti-inflammatory properties in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the upregulatio... | |||
T14003 | 15-Acetoxyscirpenol | Caspase | |
15-Acetoxyscirpenol, a member of the acetoxyscirpenol moiety mycotoxins (ASMs), potently induces apoptosis and inhibits the growth of Jurkat T cells in a dose-dependent manner. This effect is mediated through the activat... | |||
T75617 | Salviandulin E | ||
Salviandulin E, a diterpenoid isolated from Salvia leucantha CAV., exhibits antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites, demonstrating an IC50 value of 0.72 µg/mL [1] [2]. | |||
TN4587 | Mulberrofuran C | HSV | |
Mulberrofuran C shows protective effects on t-BHP-induced oxidative stress with the EC50 value of 0.41 ± 0.48 uM ; it also shows protective effects on glutamate-induced cell death with the EC50 value of 16.50 ± 7.82 uM. ... | |||
T36738 | 4′-Hydroxy-2′-methylacetophenone | ||
4′-Hydroxy-2′-methylacetophenone, a red wine aroma compound isolated from the cv. Bobal grape variety, exhibits ciliate toxicity and inhibits T. pyriformis growth with an IC50 of 0.65 mM[1][2]. | |||
T38243 | Hygrolidin | ||
Hygrolidin is a macrocyclic lactone originally isolated from S. hygroscopicus. It inhibits proliferation of a variety of cancer cell lines, including DLD-1 colon cancer, LNCaP prostate cancer, and K562 leukemia cells (IC... | |||
T81686 | Neotriptonoterpene | ||
Neotriptonoterpene, isolated from T. regelii, exhibits weak cytotoxicity against A2780, HepG2, and MCF-7 cell lines, with respective IC50 values of 65.80 µM, 35.45 µM, and 64.80 µM [1]. | |||
T38038 | (-)-Rasfonin | ||
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimot... | |||
T35910 | Petromurin C | ||
Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vit... | |||
T79998 | Celosin K | Apoptosis | |
Celosin K (compound 8), isolated from Semen Celosiae seeds, effectively inhibits t-BHP-induced neuronal injury. It mitigates oxidative stress, prevents apoptosis, and promotes autophagy [1]. | |||
T82716 | Cis-Melilotoside | ||
Cis-Melilotoside, a derivative of o-coumaric acid, exhibits potent antioxidant properties and demonstrates moderate antiprotozoal activity against T. cruzi, with an inhibitory concentration (IC 50) of 78.2 μg/mL [1] [2]. | |||
TN5880 | Mesuol | ||
Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and p... | |||
T38838 | QS-21 | Stimulon,QS-21 | |
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q... | |||
T73730 | Distamycin A | ||
Distamycin A (NSC-82150), an oligopeptide antibiotic, functions as a minor groove binder targeting B-form DNA, primarily at A/T-rich locations. It modifies enediyne-induced DNA cleavage sites and promotes apoptosis, as e... | |||
T75631 | Ganorbiformin B | ||
Ganorbiformin B, a lanostane triterpenoid, belongs to the same structural class as ganoderic acids, sharing the lanostane skeleton. It is the C-3 epimer of ganoderic acid T, known for its potent antimycobacterial activit... | |||
T75661 | Thymopentin acetate | ||
Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan... | |||
T83567 | (25R)-Spirost-4-ene-3,6,12-trione | ||
(25R)-Spirost-4-ene-3,6,12-trione is a naturally occurring compound isolated from Tribulus terrestris L. [1]. | |||
TN4778 | Physalin H | gp120/CD4 , Antifection , Autophagy | |
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunos... | |||
T14063 | 7α,25-Dihydroxycholesterol | 7α,25-OHC | EBI2/GPR183 , Endogenous Metabolite |
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cel... | |||
T75632 | Ganoderic acid T1 | ||
Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, diminishes mitochondrial membrane potential and triggers cell apoptosis by activating caspase-9 and caspase-3, thus impairing the antioxidant defense syst... | |||
T35741 | Gliovirin | ||
Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the pa... | |||
TN5033 | Skullcapflavone I | IL Receptor , Caspase , Prostaglandin Receptor | |
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep... | |||
T37609 | (rel)-Asperparaline A | ||
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) la... | |||
T36329 | Terpendole I | ||
Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and ... | |||
T35577 | Phosphatidylserines (bovine) | ||
Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on th... | |||
T36438 | Sporogen-AO 1 | ||
Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO ... | |||
T37272 | 9(S),12(S),13(S)-TriHOME | ||
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ... | |||
T35750 | Trypacidin | ||
Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, re... | |||
T35752 | Xanthoquinodin A1 | Xanthoquinodin A1 | |
Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value o... | |||
T35415 | α-D-Glucose-1,6-bisphosphate (potassium salt hydrate) | ||
α-D-Glucose-1,6-bisphosphate is abis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate syntha... | |||
T35779 | Oosporein | ||
Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectiv... | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-01235 | CD5 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-06074 | B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-01023 | CD38 Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05573 | CD38 Protein, Human, Recombinant (His), PE conjugated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02473 | ICOS Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-05156 | ICOS Protein, Human, Recombinant (rFc) | Human | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-04096 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-00849 | ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-00850 | ST2/IL-1 RL1 Protein, Human, Recombinant | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-01359 | ST2/IL-1 RL1 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn... | |||
TMPY-05322 | B7-H4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-05159 | Granzyme A/GZMA Protein, Human, Recombinant (His) | Human | HEK293 |
Granzyme A/GZMA Protein, Human, Recombinant (His) is expressed in HEK293 cells. | |||
TMPY-00817 | Granzyme B/GZMB Protein, Human, Recombinant (His) | Human | HEK293 |
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ... | |||
TMPY-02022 | CD40 Ligand Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-05096 | Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc) | Human | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-01873 | Transferrin Receptor/TFRC Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membran... | |||
TMPY-03524 | B7-H4 Protein, Human, Recombinant (His) | Human | HEK293 |
V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express... | |||
TMPY-01672 | ICOS ligand Protein, Human, Recombinant (His) | Human | HEK293 |
Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains an... | |||
TMPY-01059 | BMPR2 Protein, Human, Recombinant (His) | Human | HEK293 |
The bone morphogenetic protein type II receptor (BMPR-II, or BMPR2), a receptor for the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) superfamily. Reduced expression or function of BMPR2 signalin... | |||
TMPY-05957 | CD40 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory... | |||
TMPJ-00258 | TGF beta 2 Protein, Human, Recombinant | Human | Human Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T... | |||
TMPY-05422 | CD5 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05589 | CD5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02518 | TCL1A Protein, Human, Recombinant (His) | Human | E. coli |
T-cell leukemia/lymphoma protein 1A (abbreviated for TCL1A) is a member of the TCL1 family. TCL1 protooncogene is expressed in CD3-CD4-CD8-precursor T cells and is extinguished at the CD4+CD8+stage of thymocyte developme... | |||
TMPJ-00261 | TGF beta 2 Protein, Mouse/Rat, Recombinant | Mouse,Rat | Human Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci... | |||
TMPY-05574 | CD38 Protein, Human, Recombinant (His), FITC conjugated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05606 | CD38 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02776 | CD38 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-05273 | CD38 Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-06811 | CD38 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPJ-01186 | TRIM Protein, Human, Recombinant (His) | Human | E. coli |
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the s... | |||
TMPY-06913 | BTLA Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-06922 | BTLA Protein, Human, Recombinant (isoform1, His) | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-00175 | BTLA Protein, Human, Recombinant (hFc) | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-05142 | Blo t 1 Protein, Blomia tropicalis, Recombinant (His) | Blomia tropicalis | Yeast |
Blo t 1 Protein, Blomia tropicalis, Recombinant (His) is expressed in Yeast with His tag. The predicted molecular weight is 37.7 kDa. Accession number: A1KXI0 | |||
TMPY-06930 | BTLA Protein, Human, Recombinant (isoform1,hFc) | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-05828 | BTLA Protein, Human, Recombinant (mFc) | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-05416 | BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-06829 | BTLA Protein, Human, Recombinant (isoform 1,mFc) | Human | HEK293 |
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti... | |||
TMPY-04991 | ICOS Protein, Mouse, Recombinant (rFc) | Mouse | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-06209 | ICOS Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-05651 | ICOS Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-06979 | ICOS Protein, Human, Recombinant (His) | Human | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-01399 | ICOS Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPY-05389 | ICOS Protein, Human, Recombinant (hFc) | Human | HEK293 |
Inducible costimulator (ICOS), also called AILIM (Activation-Inducible Lymphocyte Immunomediatory Molecule) is a cell-surface receptor and belongs to the CD28 family of immune costimulatory receptors consisting of CD28, ... | |||
TMPH-02183 | CCT2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating t... | |||
TMPJ-00423 | TIM-1/KIM-1/HAVCR1 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of a... | |||
TMPJ-00641 | B7-2 Protein, Rhesus macaque, Recombinant (His) | Rhesus macaque | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm... | |||
TMPJ-00632 | B7-2 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm... | |||
TMPJ-00958 | B7-1 Protein, Rabbit, Recombinant (His) | Rabbit | Human Cells |
Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep... | |||
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