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Benzoylmesaconine

Catalog No. T6S1885 CAS 63238-67-5

Synonyms: Mesaconine 14-benzoate

Benzoylmesaconine (Mesaconine 14-benzoate) is the most abundant component of Wutou decoction, which is widely used in China because of its therapeutic effect on rheumatoid arthritis. Benzoylmesconine has analgesic activity. Benzoylmesconine may improve the resistance of T6S-mice (or thermally injured mice) to the infection of HSV-1, through the induction of antagonistic CD4+ T cells against burn-associated type-2 T cells.

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Benzoylmesaconine, CAS 63238-67-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 44.00
5 mg	In stock	$ 98.00
10 mg	In stock	$ 162.00
25 mg	In stock	$ 273.00
50 mg	In stock	$ 397.00
100 mg	In stock	$ 593.00
1 mL * 10 mM (in DMSO)	In stock	$ 139.00

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Purity: 99.78%

Purity: 97.29%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Ranunculaceae > Aconitum

Synonyms	Mesaconine 14-benzoate
Molecular Weight	589.67
Formula	C31H43NO10
CAS No.	63238-67-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 11 mg/mL (18.65 mM)

References and Literature

1. Dai PM, et al. Pharmacokinetic comparisons of benzoylmesaconine in rats using ultra-performance liquid chromatography-tandem mass spectrometry after administration of pure benzoylmesaconine and Wutou decoction. Molecules. 2014 Oct 17;19(10):16757-69. 2. Ye L, et al. Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5. Evid Based Complement Alternat Med. 2013;2013:941093. 3. Suzuki Y , Hayakawa Y , Oyama T , et al. Analgesic effect of benzoylmesaconine.[J]. Folia Pharmacologica Japonica, 1993, 102(6):399-404.

Citations

1. Chen L, Zhang C, Cao J, et al. Yiyi Fuzi Baijiang Decoction Alleviates Ulcerative Colitis Partly by Regulating TLR4-Mediated PI3K/Akt and NF-κB Pathways. Evidence-Based Complementary and Alternative Medicine. 2022, 2022.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Natural Product Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Bioactive Compounds Library Max Natural Product Library for HTS Bioactive Compound Library Anti-infective Natural Product Library NO PAINS Compound Library Selected Plant-Sourced Compound Library Tibetan medicine Compound Library

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Keywords

Benzoylmesaconine 63238-67-5 Others Mesaconine 14-benzoate Inhibitor inhibit Mesaconine inhibitor

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