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Peptide T acetate(106362-32-7 free base)

Catalog No. TP1785L CAS TP1785L

Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action

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Peptide T acetate(106362-32-7 free base) Chemical Structure

Peptide T acetate(106362-32-7 free base), CAS TP1785L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 97.00
5 mg	In stock	$ 273.00
10 mg	In stock	$ 459.00
25 mg	In stock	$ 755.00
50 mg	In stock	$ 1,060.00
100 mg	In stock	$ 1,430.00
500 mg	In stock	$ 2,860.00

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Purity: 99.47%

Biological Description

Chemical Properties

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Description	Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action
In vitro	Peptide T acts to block viral entry as it inhibits in the MAGI cell assay and blocks infection in the luciferase reporter assay using HIV virions pseudotyped with ADA envelope. Peptide T selectively inhibits HIV replication using chemokine receptor CCR5 compared to CXC4[2]. Peptide T at 10-8 M induces IL-10 production by the human Th2 cell line and PBMC. Also peptide T at 10-9 M concentration significantly inhibits IFN-g production by PBMC[3].
In vivo	Peptide T is administered subcutaneously at different doses and phases of the experimental autoimmune encephalomyelitis (EAE) disease, but Peptide T neither prevents nor ameliorates EAE[4].

Molecular Weight	917.91
Formula	C37H59N9O18
CAS No.	TP1785L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 5 mM

DMSO: Insoluble

References and Literature

1. Ruff MR, et al. Peptide T[4-8] is core HIV envelope sequence required for CD4 receptor attachment. Lancet. 1987 Sep 26;2(8561):751.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library

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Keywords

Peptide T acetate(106362-32-7 free base) TP1785L Microbiology/Virology Others Proteases/Proteasome HIV Protease Peptide T acetate(106362 32 7 free base) Peptide T acetate(106362327 free base) inhibitor inhibit

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