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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25017 | AKT-I-1 | Akt | |
AKT-I-1 is a selective and reversible inhibitor of Akt1. | |||
TP1528 | Angiotensin I/II (1-5) | Angiotensin I/II 1-5 | RAAS , Others |
Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II. | |||
TP1579 | Angiotensin I/II (1-6) | Angiotensin I/II 1-6 | RAAS , Others |
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. | |||
TP1705 | Gastrin I (1-14), human | Others | |
Gastrin I (1-14), human, represents the 1-14 peptide fragment of human gastrin I, an endogenous gastrointestinal peptide hormone. This compound is the principal hormonal regulator of gastric acid secretion. | |||
T2457 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor | IRAK |
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1. | |||
TP1122L | IGF-I 30-41 acetate(82177-09-1 free base) | Insulin-like Growth Factor I (30-41) acetate | Others |
IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). | |||
T37696 | NOS1-IN-1 | nNOS Inhibitor I | NOS |
NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorde... | |||
T7637 | Deltorphin I | Deltorphin 1,Deltorphin I(TFA),Deltorphin C | Opioid Receptor |
Deltorphin I is an agonist of δ-opioid receptor. | |||
T36622 | Angiotensin I/II (1-6) (TFA) | ||
Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angi... | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
TP1295 | Angiotensin I (human, mouse, rat) | Angiotensin 1 Human | Others |
Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in... | |||
T2045 | JANEX-1 | Jak3 inhibitor I,WHI-P131 | JAK |
JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases. | |||
TP1643 | Alpha 1(I) Collagen (614-639), human | ||
This is a peptide inhibitor of collagen fibrillar matrix assembly. | |||
T4191 | Multi-kinase inhibitor 1 | Multi-kinase inhibitor I | Others , Bcr-Abl , PDGFR , c-Kit |
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor. | |||
T32104 | Hras-1Y i-motif Probe-1 | ||
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it. | |||
TP1287 | Gastrin I (1-14), human TFA | ||
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide. | |||
TP2447 | Angiotensin I, asn(1)-val(5)-gly(9)- | ||
Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata. | |||
T8746L | I-49 free base | Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49 | Raf |
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibito... | |||
T6859 | I-BRD9 | GSK602 | Epigenetic Reader Domain |
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. | |||
T6583 | MG-101 | ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101 | Cysteine Protease , Proteasome |
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. | |||
TP1121 | IGF-I (30-41) TFA(82177-09-1,FREE) | Insulin-like Growth Factor I (30-41) (TFA) | |
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). | |||
T8955 | PCNA-I1 | Others | |
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer. | |||
T1906 | Molibresib | GSK 525762A,GSK525762,I-BET 762 | Epigenetic Reader Domain |
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM). | |||
T3984 | GLP-1(7-36), amide | MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide | Glucagon Receptor |
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-... | |||
T7084 | 2-Bromo-4'-hydroxyacetophenone | SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide | Phosphatase |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH... | |||
T3049 | TPCA-1 | GW683965,IKK2 Inhibitor IV,TPCA1 | Apoptosis , IκB/IKK , STAT |
TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes. | |||
T1830 | BX795 | IκB/IKK , Chk , CDK , c-Kit , PDK , Autophagy | |
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than... | |||
T7951 | TBK1/IKKε-IN-5 | IκB/IKK | |
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively). | |||
T15559 | TBK1/IKKε-IN-2 | IκB/IKK | |
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε. | |||
T6513 | Bisindolylmaleimide I | GF109203X,Go 6850 | PDGFR , PKC |
Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM. | |||
T131467 | 1-Hydroxylbaccatin I | ||
1-Hydroxylbaccatin I is a useful organic compound for research related to life sciences and the catalog number is T131467. | |||
T32327 | Juvocimene I | Juvocimene 1 | |
Juvocimene I and II isolated from the essential oil of sweet basil,Ocimum basilicum L are potent juvenile hormone mimics. | |||
T31360 | Deepoxy-deoxynivalenol | DOM-I,DOM-1 | |
Deepoxy-deoxynivalenol is Metabolite of deoxynivalenol. Deepoxydeoxynivalenol is a macrocyclic polyol compound for proteomics research. Environmental contaminants; Food contaminants. | |||
T62048 | Topo I-IN-1 | ||
Topo I-IN-1 (Compound 14d) is a potent Topo I inhibitor. Topo I-IN-1 exhibits antitumor activity and DNA intercalative capability. Topo I-IN-1 can induce cell apoptosis. | |||
T61720 | Pol I-IN-1 | ||
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition concentration (IC50) of 0.21 μM [1]. | |||
T63557 | HCA I-IN-1 | ||
hCA I-IN-1 is a human carbonic anhydrase I (hCA I) inhibitor that acts on hCA I (Ki: 38.3 nM), hCA II (Ki: 716.4 nM), hCAIX (Ki: 940.1 nM) and hCAXII (Ki: 192.8 nM). | |||
T64153 | Glyoxalase I inhibitor 1 | ||
Glyoxalase I inhibitor 1 is a potent inhibitor of glyoxalase I (GLO1) (IC50: 26 nM). | |||
T36170 | A1-Phytoprostane-I | A1-Phytoprostane-I | |
A1-Phytoprostane-I is a cyclopentenone isoprostane produced by the action of reactive oxygen species on α-linolenic acid in plants. There are two A1-phytoprostanes, both having the single ketone group on the ring structu... | |||
T25970 | Polymyxin B1-i | ||
Polymyxin B1-i is a polypeptide antibiotic. | |||
T81373 | Proteasome β2c/i-IN-1 | Proteasome | |
Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1]. | |||
T23869 | WEE1-IN-4 | Wee1-Inhibitor-I,Wee1 Inhibitor-I,Wee1 Inhibitor I,Wee1-Inhibitor I | |
Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor. | |||
T7461 | 2,4-Diamino-6-hydroxypyrimidine | DAHP | Reactive Oxygen Species , NO Synthase |
2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis | |||
T39591 | Human PD-L1 inhibitor I | Human PD-L1 inhibitor I | |
Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 i... | |||
T0097 | MRT67307 | MRT67307 HCl | IκB/IKK , Autophagy |
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage... | |||
T26378 | 1-Benzyl-I3C | ||
1-Benzyl-I3C is an NEDD4-1 inhibitor. | |||
T29909 | ALS-I | ALS1,Acid-Liable Surfactant-1,ALS 1,ALS-1 | |
ALS-1 is an acid-Liable surfactant. | |||
T61939 | Topo I/COX-2-IN-1 | ||
Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with the IC50 of 0.24 μM and 4.42 μM for COX-2 and Topo I, respectively. Topo I/COX-2-IN-1 induces apoptosis and inhibits migration of cancer cells, shows anti... | |||
T60450 | AChE/hCA I/II-IN-1 | ||
AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer's disease, and diabetes rsearc... | |||
T9105 | NF-κB-IN-1 | 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- | IκB/IKK , NF-κB |
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir... | |||
TP1021 | Urocortin, human | Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I | CRFR |
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2540 | 1-Hydroxybaccatin I | Others | |
1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions. | |||
T12090 | Mogroside I E1 | Others | |
Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. | |||
T2715 | Tubeimoside I | Tubeimoside-1,Lobatoside-H | Apoptosis , Others |
Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM). | |||
T3895 | Polyphyllin I | Apoptosis , Akt , JNK , PDK , mTOR , Autophagy | |
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha... | |||
T6S2123 | Ginkgolic Acid | Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),Ginkgolic acid C15:1 | Others , E1/E2/E3 Enzyme |
Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC. | |||
T12089 | Mogroside I A1 | Others | |
Mogroside I A1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, exhibiting antioxidant, antidiabetic and anticancer activities. | |||
T2961 | Notoginsenoside R1 | Sanqi glucoside R1,Sanchinoside R1 | Apoptosis , ERK , Beta Amyloid |
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties. | |||
T23645 | Aeroplysinin 1 | NSC170364,Aeroplysinin I,NSC 170364,NSC-170364 | |
Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation. | |||
TN5997 | Stipuleanoside R1 | Tarasaponin I | |
Stipuleanoside R1 is a natural product for research related to life sciences. The catalog number is TN5997 and the CAS number is 96627-79-1. | |||
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
TN7117 | Regaloside I | Others | |
Regaloside I is the monomeric component in lily. Regaloside I could be the main constituent in protecting human dermal fibroblasts from UVA-induced morphological changes [1]. | |||
T3S1227 | Aristolactam I | Aristolactam,Aristololactam I,Aristololactum | Apoptosis , Caspase |
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF... | |||
T5S2076 | Senkyunolide I | Others , Caspase | |
1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties. | |||
T3S1892 | Crassicauline A | Crassicauline I | Others |
1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively. | |||
T2873 | Ginsenoside Rg2 | Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2 | Beta Amyloid , GSK-3 , NF-κB |
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor. | |||
T10233 | Acetylarenobufagin | HIF | |
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator. | |||
TN1420 | Bacopaside I | Others | |
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ... | |||
T3S0335 | Soyasaponin Bb | Soyasaponin I | NF-κB , Caspase |
1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa... | |||
T5S0167 | Atractylenolide I | IL Receptor , TNF , TLR , JAK , STAT | |
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide... | |||
T5S1262 | Methylophiopogonanone A | Others | |
1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulati... | |||
T4A2458 | Resibufogenin | Bufogenin,Recibufogenin | Others |
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff... | |||
T3S2072 | 3-Butylidenephthalide | Butylidene phthalide,n-Butylidenephthalide | Parasite , Glucosidase |
1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv... | |||
T3S1873 | Talatisamine | Potassium Channel | |
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat... | |||
T3S0057 | Dihydrochelerythrine | 12,13-Dihydrochelerythrine | Antifungal |
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
TCS1704 | Artemitin | Artemetin,Artemisetin,Erianthin | Antioxidant |
1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenou... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
TN4661 | Nodosin | IL Receptor , Autophagy | |
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp... | |||
T5S0527 | Rhodojaponin III | Others | |
1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja... | |||
T2S1792 | Lycobetaine | Ungeremine | Antibacterial |
1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively... | |||
TCS2170 | 2,5-Dihydroxyacetophenone | Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP | ERK , NF-κB , Tyrosinase |
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... | |||
T6S1418 | Praeruptorin C | Antioxidant , Calcium Channel | |
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ... | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T3339 | Sophoridine | 5-Epidihydrosophocarpine,Dihydro-5-episophocarpine | Apoptosis , Topoisomerase |
Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivatives were synthesized and evaluated for their cytotoxicity ... | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T4S2326 | Cornuside | 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside | ERK , p38 MAPK , NF-κB , JNK |
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T6S1572 | Sauchinone | ERK , p38 MAPK , NF-κB | |
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative... | |||
T83378 | 2-Methoxy-6-pentadecyl-1,4-benzoquinone | ||
2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c), a pentadecyl derivative, is isolatable from seed oils of various Iris species, including I. pseudacorus, I. missouriensis, and I. sibirica [1]. | |||
TN5675 | Ganomycin I | ||
Ganomycin I inhibits the activity of HIV-1 protease. | |||
T81920 | LNnDFH I | Lacto-N-neo-difucohexaose I | |
LNnDFH I, a natural product, can be isolated from human urine [1]. | |||
T81765 | Monofucosyllacto-N-hexaose I | MFLNH I | |
Monofucosyllacto-N-hexaose I (MFLNH I) constitutes a human milk oligosaccharide (HMO) [1]. | |||
T81887 | Macrostemonoside I | ||
Macrostemonoside I, a furostanol saponin, can be isolated from Allium macrostemon [1]. | |||
T81961 | Lacto-N-difucohexaose I | LDFH I | |
Lacto-N-difucohexaose I (LNDFH I), a connecting agent, may facilitate the attachment of Lewis b sugar chain-bearing oligosaccharides to water-insoluble polysaccharides [1]. | |||
T82690 | Complanatin I | ||
Complanatin I, a natural product, is isolated from Astragalus complanatus [1]. | |||
TN1169 | 1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside | 1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside | Topoisomerase |
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside may have DNA topoisomerases I and II inhibitory activity and cytotoxicity. | |||
T82270 | Goshuyuamide I | ||
Goshuyuamide-I (compound 4), an alkaloid, can be isolated from the fruits of Euodia rutaecarpa and is utilized in analgesic research [1]. | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-03855 | DNase I Protein, Human, Recombinant (His) | Human | HEK293 Cells |
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos... | |||
TMPY-02899 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.2 kDa and the accession number is Q00623. | |||
TMPY-06982 | IGF1/IGF-I Protein, Human, Recombinant | Human | E. coli |
IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1. | |||
TMPY-02767 | TPP1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
TPP1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.7 kDa and the accession number is AAH14863.1. | |||
TMPY-00695 | I-309 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
I-309 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is P22362. | |||
TMPY-04853 | TSHR Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre... | |||
TMPY-04878 | IGF1/IGF-I Protein, Mouse, Recombinant | Mouse | P. pastoris (Yeast) |
IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89. | |||
TMPY-02553 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) | Mouse | HEK293 Cells |
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.8 kDa and the accession number is Q00623. | |||
TMPY-04625 | SEMA3A Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is A0A803Z7F8. | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPY-02956 | Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney... | |||
TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPY-01168 | ALK-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ALK-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.3 kDa and the accession number is A0A0S2Z310. | |||
TMPY-01047 | IL-1R1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IL-1R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is P14778. | |||
TMPY-02371 | ST6GAL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
ST6GAL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.9 kDa and the accession number is Q64685. | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069. | |||
TMPY-04774 | ALK-2/ACVR1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
ALK-2/ACVR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.8kDa and the accession number is Q04771. | |||
TMPY-00124 | SEMA3A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SEMA3A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is Q14563. | |||
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
TMPJ-00702 | APT-1 Protein, Human, Recombinant (His) | Human | E. coli |
Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1... | |||
TMPY-05215 | TPP1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
TPP1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.9 kDa and the accession number is O89023. | |||
TMPY-02142 | IL-1R1 Protein, Rat, Recombinant (His & mFc) | Rat | HEK293 Cells |
IL-1R1 Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag. The predicted molecular weight is 64.6 kDa and the accession number is A6INN1. | |||
TMPY-03744 | IL-1R1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
IL-1R1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.4 kDa and the accession number is G8F337. | |||
TMPY-03688 | IL-1R1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
IL-1R1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.6 kDa and the accession number is G7NAT4. | |||
TMPY-02059 | IL-1R1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
IL-1R1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is A6INN1. | |||
TMPJ-00731 | Carbonic Anhydrase 1 Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 p... | |||
TMPY-03449 | CPNE1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
CPNE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 59.2 kDa and the accession number is Q99829. | |||
TMPY-03265 | CPNE1 Protein, Human, Recombinant (SUMO) | Human | Baculovirus Insect Cells |
CPNE1 Protein, Human, Recombinant (SUMO) is expressed in Baculovirus insect cells with SUMO tag. The predicted molecular weight is 72.7 kDa and the accession number is Q99829. | |||
TMPJ-01142 | CDO1 Protein, Human, Recombinant (His) | Human | E. coli |
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan... | |||
TMPJ-01291 | CPNE1 Protein, Human, Recombinant (His) | Human | E. coli |
Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not co... | |||
TMPJ-00158 | Apolipoprotein A-I/APOA1 Protein, Human, Recombinant | Human | E. coli |
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various... | |||
TMPY-06955 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is Q00623. | |||
TMPY-04942 | IGF1 LR3 Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1. | |||
TMPJ-00789 | Flagellin Protein, Salmonella Typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin... | |||
TMPK-00799 | ANXA1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPJ-00528 | PPP1R1A Protein, Human, Recombinant (His) | Human | E. coli |
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein pla... | |||
TMPK-01291 | ANXA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPK-00768 | ANXA1 Protein, Human, Recombinant (His) | Human | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPJ-00814 | RBP1 Protein, Human, Recombinant | Human | E. coli |
RBP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14 KDa and the accession number is P09455. | |||
TMPK-00774 | TrkA Protein, Human, Recombinant (aa 33-417, His) | Human | HEK293 Cells |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa... | |||
TMPY-01158 | CD38 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD38 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P56528. | |||
TMPY-06651 | CD38 Protein, Mouse, Recombinant | Mouse | HEK293 Cells |
CD38 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 29.80 kDa and the accession number is NP_031672.2. | |||
TMPH-03258 | Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Reversible hydration of carbon dioxide. Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.2 kDa and the acce... | |||
TMPJ-01311 | EPT1 Protein, Human, Recombinant (GST) | Human | E. coli |
Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The ... | |||
TMPH-00223 | Alpha-S2-casein Protein, Bovine, Recombinant (His & KSI) | Bovine | E. coli |
Important role in the capacity of milk to transport calcium phosphate.; Casocidin-I inhibits the growth of E.coli and S.carnosus. Alpha-S2-casein Protein, Bovine, Recombinant (His & KSI) is expressed in E. coli expressio... | |||
TMPJ-00240 | CAMK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed.... | |||
TMPY-00320 | APOA1BP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites... | |||
TMPY-06726 | Car i 1 Protein, Pecan, Recombinant | Pecan | E. coli |
Car i 1 Protein, Pecan, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa. | |||
TMPJ-01176 | SEMA4C Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. P... | |||
TMPY-02729 | IL-1R1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
IL-1R1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.3 kDa and the accession number is P13504. | |||
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