Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 52.00 | |
10 mg | In stock | $ 89.00 | |
25 mg | In stock | $ 153.00 | |
50 mg | In stock | $ 238.00 | |
100 mg | In stock | $ 397.00 |
Description | Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction. |
Source |
Molecular Weight | 855.02 |
Formula | C44H70O16 |
CAS No. | 50773-41-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 117 mM
You can also refer to dose conversion for different animals. More
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Polyphyllin I 50773-41-6 Apoptosis Autophagy Cytoskeletal Signaling MAPK PI3K/Akt/mTOR signaling Akt JNK PDK mTOR PDK-1 Protein kinase B PKB inhibit Mammalian target of Rapamycin Inhibitor inhibitor