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MG-101

Catalog No. T6583 CAS 110044-82-1

Synonyms: ALLN, Ac-LLnL-CHO, Calpain inhibitor I, Calpain inhibitor-1, MG101

MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

MG-101, CAS 110044-82-1

Pack Size	Availability	Price/USD
5 mg	In stock	$ 48.00
10 mg	In stock	$ 74.00
25 mg	In stock	$ 157.00
50 mg	In stock	$ 249.00
100 mg	In stock	$ 397.00
1 mL * 10 mM (in DMSO)	In stock	$ 54.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.
In vitro	AI-10-49 displays specific growth inhibition of inv(16)-positive cell line ME-1. AI-10-49 selectively binds to CBFβ-SMMHC, disrupts its binding to RUNX1, and restores RUNX1 transcriptional activity. [1]

Synonyms	ALLN, Ac-LLnL-CHO, Calpain inhibitor I, Calpain inhibitor-1, MG101
Molecular Weight	383.53
Formula	C20H37N3O4
CAS No.	110044-82-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 76 mg/mL (198.15 mM)

DMSO: 76 mg/mL (198.15 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Hiwasa T, et al. Carcinogenesis. 1990, 11(1), 75-80. 2. Inoue S, et al. J Biol Chem. 1991, 266(20), 13311-13317.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compounds Library Max NO PAINS Compound Library Bioactive Compound Library Anti-Aging Compound Library Ubiquitination Compound Library Protease Inhibitor Library Anti-COVID-19 Compound Library Covalent Inhibitor Library Apoptosis Compound Library

Related Products

Related compounds with same targets

Cathepsin Inhibitor 1 Calpeptin Z-Lys-OH (RS)-Butyryltimolol Esomeprazole E-64 L-006235 VBY-825

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MG-101 110044-82-1 Proteases/Proteasome Ubiquitination Cysteine Protease Proteasome RKO ALLN colon cancer Bax HepG2 MG 101 Inhibitor mitochondria Ac-LLnL-CHO HCT116 inhibit Calpain inhibitor I Apoptosis SW480 Calpain inhibitor-1 MG101 anti-tumor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.