Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 123.00 | |
2 mg | In stock | $ 172.00 | |
5 mg | In stock | $ 263.00 | |
10 mg | In stock | $ 413.00 | |
25 mg | In stock | $ 692.00 | |
50 mg | In stock | $ 985.00 | |
100 mg | In stock | $ 1,330.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 265.00 |
Description | TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε. |
Targets&IC50 | TBK1:0.6 nM (IC50, at 5 μM ATP) , IKKε:3.9 nM (IC50, at 10 μM ATP) |
In vitro | TBK1/IKKε-IN-2 (Cmpound #1) inhibits TBK1 biochemical function in Ulight kinase assay at 5 and 250 μM ATP concentration with IC50s of 0.6 and 2.6 nM, rsespectively. TBK1/IKKε-IN-2 inhibits IKKε biochemical function in Ulight kinase assay at 10 μM ATP with an IC50 of 3.9 nM. The IC50 of TBK1/IKKε-IN-2 in the Panc 02.13 proliferation assay is 5 μM[1]. |
Molecular Weight | 457.52 |
Formula | C26H27N5O3 |
CAS No. | 1292310-49-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16.5 mg/mL (36.06 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TBK1/IKKε-IN-2 1292310-49-6 NF-Κb IκB/IKK TBK1/IKKεIN2 IKK IκB kinase inhibit TBK-1/IKKε-IN-2 TBK1/IKKε IN 2 I kappa B kinase Inhibitor inhibitor