Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation .
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 65.00 | |
2 mg | In stock | $ 92.00 | |
5 mg | In stock | $ 142.00 | |
10 mg | In stock | $ 222.00 | |
25 mg | In stock | $ 448.00 | |
50 mg | In stock | $ 677.00 | |
100 mg | In stock | $ 963.00 | |
500 mg | In stock | $ 1,930.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 156.00 |
Description | 1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological effects on central nervous system. 3. Resibufogenin corrects hypertension in a rat model of human preeclampsia, it not only prevents the advent of hypertension and proteinuria, but also the development of intrauterine growth restriction.4. Resibufogenina's major metabolic pathway in the human liver is CYP3A4 dominantly mediated 5β-hydroxylation . |
Synonyms | Bufogenin, Recibufogenin |
Molecular Weight | 384.51 |
Formula | C24H32O4 |
CAS No. | 465-39-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (143.04 mM)
You can also refer to dose conversion for different animals. More
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Resibufogenin 465-39-4 Others inhibit Inhibitor Bufogenin Recibufogenin inhibitor