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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13074 | TAM-IN-2 | TAM Receptor | |
TAM-IN-2 is an inhibitor of TAM. | |||
T64185 | TAM&Met-IN-1 | ||
TAM&Met-IN-1 is a potent inhibitor of TAM and c-Met, acting on AXL (IC50: 6.1 nM), MER (IC50: 13.2 nM) and TYRO3 (IC50: 21.6 nM). TAM&Met-IN-1 can be used in anticancer studies. | |||
T7425 | RU-301 | TAM Receptor | |
RU-301 is a novel pan-tam inhibitor | |||
T1968 | UNC2250 | TAM Receptor | |
UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM). | |||
T6982 | SGI-7079 | FLT , c-Met/HGFR , c-RET , TAM Receptor , Src | |
SGI-7079 is a new selective Axl inhibitor. SGI-7079 can be a dose-dependent manner inhibited growth of tumors. It is also a potential therapeutic target for EGFR inhibitor resistance. | |||
T2311 | LDC1267 | TAM Receptor | |
LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM). | |||
T17205 | UNC2541 | Others , FLT , TAM Receptor | |
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM). | |||
T2005 | Dubermatinib | TP0903 | Apoptosis , TAM Receptor |
Dubermatinib (TP0903) is a potent and selective Axl kinase inhibitor. | |||
TQ0041 | Ningetinib Tosylate | VEGFR , c-Met/HGFR , TAM Receptor | |
Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively. | |||
T6907 | NPS-1034 | NPS1034,NPS 1034 | Apoptosis , c-Met/HGFR , TAM Receptor |
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively. | |||
T2629 | UNC2881 | TAM Receptor | |
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively. | |||
T21302 | UNC569 | UNC 569 | TAM Receptor |
UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amoun... | |||
T4426 | CEP-40783 | CEP 40783,RXDX-106 | c-Met/HGFR , TAM Receptor |
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM). | |||
T9123 | DS-1205 | TAM Receptor | |
DS-1205 is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205 also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205 can inhibit cell migration in vitro an... | |||
T8327 | ONO-7475 | Trk receptor , TAM Receptor | |
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase | |||
T6269 | Bemcentinib | R428,BGB324 | TAM Receptor |
Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated for the treatment of NSCLC. | |||
TQ0021 | Ningetinib | CT-053,CT053PTSA | VEGFR , c-Met/HGFR , TAM Receptor |
Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively. | |||
T2699 | BMS 777607 | BMS777607,BMS-777607,BMS 817378 | c-Met/HGFR , TAM Receptor |
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met/Axl/Ron/Tyro3 (IC50: 3.9/1.1/1.8/4.3 nM). BMS-777607 has been investigated for the basic science of Malignant Solid Tumour. | |||
T4409 | Gilteritinib | ASP2215 | FLT , TAM Receptor , c-Kit |
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an... | |||
T7379 | 2-D08 | E1/E2/E3 Enzyme , TAM Receptor | |
2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect. | |||
T9052 | XL092 | CL-092,JUN04542 | VEGFR , c-Met/HGFR , TAM Receptor |
XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders. | |||
T2586 | Cabozantinib | XL184,BMS-907351 | Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit |
Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity... | |||
T5164 | Cabozantinib hydrochloride | XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351 | VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR |
Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM). | |||
T77493 | Murlentamab | 3C23K,GM102 | Others |
Murlentamab (GM102) is a humanized anti-AMhRII antibody. Murlentama has potential antitumor activity that induces macrophage-mediated antitumor-dependent cell-mediated cytotoxic effects (ADCC). Murl can stimulate the pro... | |||
T20331 | Sodium lauroyl glutamate | Hostapon CLG,Amisoft LS 11,Sodium N-lauroylglutamate,Acylglutamate LS-11 | Others |
Sodium lauroyl glutamate (Acylglutamate LS-11) is an amino acid detergent and increases the solubility of long-chain alkyl gallates such as alkyl gallates. | |||
T12146 | N-Desmethyl-Apalutamide | N-Desmethyl Apalutamide | P450 , Androgen Receptor |
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. | |||
T6652 | Salbutamol hemisulfate | Ventolin Sulfate,Albuterol,Salbutamol Sulfate,Bronchospray,Albuterol Sulfate | Adrenergic Receptor , Autophagy |
Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM. | |||
T77448 | Naxitamab | Naxitamab-gqgk,Humanized 3F8,Hu3F8 | Others |
Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers. | |||
T76890 | Petosemtamab | MCLA 158 | EGFR |
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM). Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab... | |||
T14054 | 5-TAMRA-SE | 5-Carboxytetramethylrhodamine succinimidyl ester,5-TAMRA-NHS ester | Others |
5-TAMRA-SE, an amine-reactive fluorescent agent, forms conjugates that produce bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) and exhibit good photostability. | |||
T77129 | Belantamab | GSK2857914 | TNF |
Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantama... | |||
T76877 | Vofatamab | RG-7444,B-701,MFGR-1877S | FGFR |
Vofatamab (B-701) is a fully human monoclonal antibody targeting FGFR3. Vofatamab has potential anticancer and antitumor activity and is often used in combination with other compounds to treat cancer. | |||
T8706 | STAMBP-IN-1 | Others | |
STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism. | |||
T9153 | Picotamide | Others | |
Picotamide has anticoagulant and fibrinolytic properties. | |||
T35427 | β-Lactamase-IN-2 | Antibacterial | |
β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects. | |||
T3987 | Lotamilast | E6005,RVT-501 | PDE |
Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis. | |||
T7642 | Cilostamide | OPC3689 | PDE |
Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively) | |||
T7120 | Cefetamet pivoxil hydrochloride | Ro 15-8075 | Antibacterial , Antibiotic |
Cefetamet pivoxil hydrochloride (Ro 15-8075) is a third generation cephalosporin antibiotic with oral activity. | |||
T0697 | Aspartame | SC-18862 | Others , Taste receptor |
Aspartame (SC-18862), an artificial, non-carbohydrate sweetener, is aspartyl-phenylalanine-1-methyl ester. | |||
T6694 | Tamibarotene | NSC 608000,Am 80,Amnolake | Apoptosis , Retinoid Receptor , Autophagy |
Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. | |||
T8217 | Enzalutamide carboxylic acid | Androgen Receptor , Drug Metabolite | |
Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) . | |||
T17210 | Vaborbactam | RPX7009 | Antibacterial |
Vaborbactam (RPX7009) is a β-lactamase inhibitor that is often used in conjunction with meropenem to study pneumonia and CRE infections. | |||
T13077 | Taniborbactam dihydrochloride | VNRX-5133 dihydrochloride,Taniborbactam 2HCl | Antibacterial , Antifungal |
Taniborbactam dihydrochloride (VNRX-5133 dihydrochloride) is a selective and potent novel cyclic boronic acid β-lactamase inhibitor with antimicrobial activity and significant inhibition of Gram-negative bacteria.Tanibor... | |||
T10335 | Antihistamine-1 | P450 | |
Antihistamine-1 is an H1-antihistamine (Ki: 6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel (IC50s: 5.4 and 0.8 μM). | |||
T33868 | Palmitoyl glutamic acid | N-Palmitoyl-L-glutamic acid,Palmitoylglutaminic acid | |
Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) is an acyl amino acid that blocks aortic constriction and antagonizes haloperidol-induced oral motility disorders. | |||
T12166 | Nacubactam | OP0595 free acid | Antibacterial |
Nacubactam (OP0595 free acid) is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases. | |||
T1654 | Pentamidine isethionate | Pentamidine isethionate salt,Pentamidine diisethionate | Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal |
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent. | |||
T7863 | Hexamethylene bisacetamide | Epigenetic Reader Domain | |
Hexamethylene bisacetamide inhibits BET Bromodomain Proteins. | |||
T20365 | Monopotassium glutamate | Potassium glutamate,Potassium L-glutamate | Others |
Monopotassium glutamate (Potassium glutamate) can be used in foods as a flavor enhancer. | |||
T20386 | Caprolactam | Others | |
Caprolactam is a natural product used in the manufacture of synthetic fibers of the polyamide type. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9371 | DL-Pyroglutamic acid | Others | |
DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen. | |||
T13681 | Epi-galantamine | AChE | |
Epi-galantamine, a diastereomer of galantamine, is an alkaloid extracted from the bulbs and flowers of the Caucasian snowdrop (Galanthus woronowii). It acts as an AChE inhibitor, featuring an EC50 of 45.7 μM. | |||
T12139 | N-(3-Methoxybenzyl)Palmitamide | FAAH | |
N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders. | |||
T0769 | Aceglutamide | N2-Acetylglutamine,α-N-Acetyl-L-glutamine | Amino Acids and Derivatives , Endogenous Metabolite , Autophagy |
Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory. | |||
T4834 | Indole-3-acetamide | 3-Indoleacetamide,3-Indolylacetamide | Others , Endogenous Metabolite |
1H-Indole-3-acetamide (3-Indolylacetamide), also known as auxin amide or 2-(3-indolyl)acetamide, belongs to the class of organic compounds known as 3-alkylindoles. Within the cell, 1H-indole-3-acetamide is primarily loca... | |||
T4860 | 5-Hydroxytryptamine creatinine sulfate monohydrate | Serotonin creatinine sulfate monohydrate,5-Hydroxytryptamine creatinine sulfate complex | Others , Endogenous Metabolite |
5-Hydroxytryptamine creatinine sulfate monohydrate (Serotonin creatinine sulfate monohydrate) is a neurotransmitter. | |||
T4933 | (S)-2-acetamido-4-amino-4-oxobutanoic acid | Nα-Acetyl-L-asparagine | Endogenous Metabolite |
(S)-2-acetamido-4-amino-4-oxobutanoic acid (Nα-Acetyl-L-asparagine), also known as acasn, is an endogenous metabolite. | |||
T8790 | 1-Methylhistamine dihydrochloride | Endogenous Metabolite | |
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains... | |||
T1075 | Vitamin K1 | Phylloquinone,Phytomenadione,Phytonadione,Phyllohydroquinone | Others , Endogenous Metabolite |
Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity. | |||
T0326L | L-Glutamine | L-Glutamic acid 5-amide | Ferroptosis , Endogenous Metabolite , GluR |
L-Glutamine (L-Glutamic acid 5-amide) , a non-essential amino acid, is synthesized from glutamic acid and ammonia. | |||
T1040 | Vitamin B12 | Cyanocobalamin,Cobalamin | Endogenous Metabolite |
Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes... | |||
T0647 | Tryptamine | Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r... | |||
T19443 | N-Acetylhistamine | N-Omega-acetylhistamine | Endogenous Metabolite , Histamine Receptor |
N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine. | |||
T2A2497 | L-Glutamic acid | (S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,glutacid,Glutaminol | Apoptosis , Ferroptosis , Endogenous Metabolite , iGluR |
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals. | |||
T8149 | Dobutamine hydrochloride | Dobutamine (hydrochloride) | Adrenergic Receptor |
Dobutamine hydrochloride (Dobutamine (hydrochloride)) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects. | |||
T12016 | Methyl L-pyroglutamate | L-Pyroglutamic acid methyl ester,(S)-Methyl 5-oxopyrrolidine-2-carboxylate | Others |
Methyl L-pyroglutamate (L-Pyroglutamic acid methyl ester) shows anti-inflammatory activity. Methyl L-pyroglutamate is isolated from Portulaca oleracea L.. | |||
T0326 | DL-Glutamine | Glutamin,DL-Gl,(±)-Glutamine,2-amino-4-carbamoylbutanoic acid | Ferroptosis , Amino Acids and Derivatives , Endogenous Metabolite |
DL-Glutamine (2-amino-4-carbamoylbutanoic acid), a non-essential amino acid, exists abundantly throughout the body and is participated in many metabolic processes. It is synthesized from glutamic acid and ammonia, and is... | |||
T1214 | Ribostamycin sulfate | Vistamycin sulfate | Antibacterial , Antibiotic |
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome. | |||
T20754 | Deltamethrin | Butoss,RU-22974,Esbecythrin,K-Othrin,Decamethrin,RU 22974 | Others |
Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, co... | |||
T6468 | D-glutamine | Mitophagy , Ferroptosis , Endogenous Metabolite , GluR , Autophagy | |
D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code. | |||
T1135 | Vitamin D3 | Cholecalciferol,Colecalciferol | Endogenous Metabolite |
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR). | |||
T1354 | N-Acetyl-5-hydroxytryptamine | Normelatonin,O-Demethylmelatonin,N-Acetylserotonin | Trk receptor , Endogenous Metabolite |
N-Acetyl-5-hydroxytryptamine (O-Demethylmelatonin) , also known as Normelatonin, is the immediate precursor of melatonin. It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to m... | |||
T0436 | 6-Acetamidohexanoic acid | 6-Acetamidocaproic acid,Acexamic Acid | Amino Acids and Derivatives , COX |
6-Acetamidohexanoic acid (Acexamic Acid) is a kind of amino acids deriviate. | |||
T2570 | Vitamin K4 | Kapilin,Menadiol Diacetate,acetomenaphthone | Apoptosis , Endogenous Metabolite |
Vitamin K4 (Menadiol Diacetate) is a vitamin medicine for the treatment of blood coagulation disorders that caused by the lack of VK4. | |||
T5217 | 2-(2-Phenylacetamido)acetic acid | Phenaceturic acid,Phenyl-ac-Gly-OH,Phenylacetyl glycine | Others , Endogenous Metabolite |
2-(2-Phenylacetamido)acetic acid (Phenyl-ac-Gly-OH) is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. The presence of phenylacetylglycine in urine has been confirmed for dogs, rats, and mic... | |||
T5267 | N-Acetyl-L-glutamic acid | Ac-L-Glu-OH,N-Acetylglutamic acid | Others , Endogenous Metabolite |
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phospha... | |||
TN7063 | N-Acetaminophen | NSC 403155,N-Acetyldemecolcine,N-Methylcolchicine,N-Acetylcolchamine | Others |
N-Acetaminophen (N-Methylcolchicine) is a methylated form of Colchicine. | |||
T7916 | 4-Acetamidobenzenesulfonyl azide | Others | |
4-Acetamidobenzenesulfonyl azide is used in a variety of scientific research applications, including the synthesis of drugs, peptides and other biologically active molecules. It is also used as a catalyst in polymerizati... | |||
T2336 | Vitamin K2 | Menatetrenone | Endogenous Metabolite |
Vitamin K2 (Menatetrenone) is a menaquinone compound and form of vitamin K2 with potential antineoplastic activity. Menatetrenone may act by modulating the signaling of certain tyrosine kinases, thereby affecting several... | |||
T0965 | Histamine | Ergamine | 5-HT Receptor , Endogenous Metabolite , Histamine Receptor |
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... | |||
T3409 | Plantamajoside | Y0160,C10485 | Others |
Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity. | |||
T1648 | α-Vitamin E | Dexrabeprazole Sodium,Vitamin E,Alpha-Tocopherol,D-α-Tocopherol,5,7,8-Trimethyltocol,(+)-alpha-Tocopherol | Others , Ferroptosis , Influenza Virus , Reactive Oxygen Species , Endogenous Metabolite , Antibacterial , PKC , GST |
α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. | |||
T0709 | Natamycin | Pimaricin | Estrogen/progestogen Receptor , Endogenous Metabolite , Antibiotic , Antifungal |
Natamycin (Pimaricin) is a Polyene Antimicrobial. | |||
T6871 | L-Glutamic acid monosodium salt | Monosodium glutamate,Glutacyl,Glutavene,Ajinomoto,MSG | Apoptosis , Ferroptosis , GluR , iGluR |
L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor. | |||
T1086 | Vitamin D2 | Calciferol,Ergocalciferol,Ercalciol | DNA/RNA Synthesis , Endogenous Metabolite |
Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it in... | |||
T41031 | Protamine sulfate | Thrombin | |
Protamine sulfate is a polycationic peptide that serves as an antiheparin agent. This compound can neutralize the anticoagulant action of heparin and enhance lipid-mediated gene transfer. | |||
T0065 | Acetaminophen | 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol | COX , Endogenous Metabolite , Histone Acetyltransferase |
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity. | |||
T2A2486 | 3',4',5',5,7-Pentamethoxyflavone | 5,7,3',4',5'-Pentamethoxyflavone | Nrf2 |
3',4',5',5,7-Pentamethoxyflavone is a naturally occurring brassinosteroid compound from the Rutaceae family that exhibits resistance to cancer cells by inhibiting the Nrf2 pathway to overcome chemotherapeutically active ... | |||
T5222 | N-(5-Aminopentyl)acetamide | Monoacetylcadaverine,N-Acetylcadaverine,N-Acetyl-1,5-pentanediamine | Others , Endogenous Metabolite |
N-(5-Aminopentyl)acetamide (N-Acetylcadaverine) is the acetylated form of the polyamine cadaverine. Cadaverine is produced by the breakdown of amino acids in living and dead organisms and is toxic in large doses. N-(5-Am... | |||
T4940 | 3-Methylhistamine dihydrochloride | Others , Endogenous Metabolite | |
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere... | |||
T1326 | Gentamicin sulfate | SCH9724,Gentamycin sulfate,NSC-82261 | ribosome , DHFR , Antibacterial , Antibiotic |
Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms. | |||
T14008 | 2,2,5,7,8-Pentamethyl-6-Chromanol | PMC | Androgen Receptor |
2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines. | |||
TN2121 | 3,5,7,3′,4′-Pentamethoxyflavone | Quercetin 3,5,7,3,4-pentamethyl ether | Others |
3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product. It can induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T10935 | D-Glutamic acid | (R)-Glutamic acid | Endogenous Metabolite |
D-Glutamic acid ((R)-Glutamic acid), the enantiomer of L-glutamic acid, is widely used in medicine and food. | |||
TN1039 | Tamarixetin | 4'-O-Methyl Quercetin | Endogenous Metabolite , Immunology/Inflammation related |
Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy. | |||
T0507 | L-Pyroglutamic acid | pidolic acid,L-pyroglutamate,5-Oxoproline | Others , Endogenous Metabolite |
L-Pyroglutamic acid (pidolic acid), a cyclized derivative of the L-GLUTAMIC ACID, can elevate blood levels. This function may be associated with problems of GLUTATHIONE or GLUTAMINE metabolism. | |||
T3S1227 | Aristolactam I | Aristolactam,Aristololactam I,Aristololactum | Apoptosis , Caspase |
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF... | |||
T19603 | Vitamin K | Kephton,Vitamin K1(20) | Endogenous Metabolite |
Vitamin K (Kephton) has blood coagulation action and is important for coagulation factors, matrix-Gla protein, and osteocalcin. | |||
T41054 | γ-Glutamyl-S-allylcysteine | L-γ-Glutamyl-(S)-Allyl-Cysteine | Antioxidant |
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a γ-glutamyl peptide extracted from Allium sativum L. γ-Glutamyl-S-allylcysteine possesses anti-glycation and antioxidant activities, and can inhibit the ch... | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-01605 | STIM1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human ... | |||
TMPY-01355 | Transglutaminase 2/TGM2 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth an... | |||
TMPY-02706 | Vitamin D Receptor/VDR Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Vitamin D Receptor/VDR Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P11473. | |||
TMPY-05055 | GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His) | Human | HEK293 Cells |
gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expres... | |||
TMPJ-00429 | CRTAM Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
CRTAM Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is A0A2K5TKL4. | |||
TMPY-02987 | Vitamin D Receptor/VDR Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
Vitamin D Receptor/VDR Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.28 kDa and the accession number is P48281. | |||
TMPH-00587 | Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4... | |||
TMPH-03474 | Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Has cefotaxime-hydrolyzing activity. Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28.4 kDa and the accession number is P... | |||
TMPY-02129 | Transglutaminase 3/TGM3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutamina... | |||
TMPH-00584 | Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPK-00971 | CRTAM Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I... | |||
TMPJ-01422 | CRTAM Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
CRTAM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-60 KDa and the accession number is XP_005580021.1. | |||
TMPY-05870 | Influenza A H1N1 (A/swine/Saitama/21/2004) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 Cells |
Influenza A H1N1 (A/swine/Saitama/21/2004) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is F5HQJ0. | |||
TMPK-01385 | CRTAM Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of I... | |||
TMPH-00939 | Anoctamin-5/ANO5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anoctamin-5/ANO5 Protein, Human, Recombinant (His) is expressed in HEK293. | |||
TMPH-00515 | PPDK Protein, Entamoeba histolytica, Recombinant (His & SUMO) | Entamoeba histolytica | E. coli |
Catalyzes the reversible phosphorylation of pyruvate and phosphate. In E.histolytica and C.symbiosus, PPDK functions in the direction of ATP synthesis. | |||
TMPH-00586 | Beta-lactamase TEM Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4... | |||
TMPH-02373 | Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) | Klebsiella pneumoniae | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol... | |||
TMPH-00940 | Anoctamin-5/ANO5 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Anoctamin-5/ANO5 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-03488 | Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) | Serratia marcescens | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant ... | |||
TMPH-03164 | Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight... | |||
TMPH-00795 | Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc) | Helicobacter pylori | E. coli |
Provides the (R)-glutamate required for cell wall biosynthesis. Glutamate racemase Protein, Helicobacter pylori, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicte... | |||
TMPH-00588 | Beta-lactamase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
TMPY-01674 | CRTAM Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like... | |||
TMPH-03165 | Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735. | |||
TMPH-00585 | Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His) | E. coli | P. pastoris (Yeast) |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPY-04830 | GAS6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ... | |||
TMPY-04396 | C-ABL/ABL1 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy... | |||
TMPK-00472 | AXL Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre... | |||
TMPK-00517 | GAS6 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of ... | |||
TMPK-00410 | AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre... | |||
TMPK-00408 | AXL Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre... | |||
TMPK-00407 | AXL Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre... | |||
TMPJ-00365 | GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signa... |
Cat No. | Product Name | ||
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L9820 | Beta-Lactam Compound Library | 97 compounds | |
A unique collection of 97 beta-lactam compounds, can be used in HTS and HCS; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... | |||
L3300 | Histamine & Melatonin Receptor-Targeted Compound Library | 153 compounds | |
A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; |