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Vitamin B12

Catalog No. T1040 CAS 68-19-9

Synonyms: Cyanocobalamin, Cobalamin

Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.

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Vitamin B12, CAS 68-19-9

Pack Size	Availability	Price/USD
200 mg	In stock	$ 31.00
500 mg	In stock	$ 53.00
1 mL * 10 mM (in DMSO)	In stock	$ 57.00

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Purity: 99.9%

Purity: 99.54%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Cyanocobalamin, Cobalamin
Molecular Weight	1355.37
Formula	C63H88CoN14O14P
CAS No.	68-19-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 10 mg/mL (7.37 mM)

H2O: 6 mg/mL (4.42 mM)

DMSO: 70 mg/mL (51.6 mM)

References and Literature

1. Ghazanfari S, et al. Drug Res (Stuttg). 2014 Mar;64(3):113-7.

Related compound libraries

This product is contained In the following compound libraries：

Human Endogenous Metabolite Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Microbial Natural Product Library Traditional Chinese Medicine Monomer Library Inactive Ingredient Library Nucleotide Compound Library FDA-Approved & Pharmacopeia Drug Library NO PAINS Compound Library

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You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Vitamin B12 68-19-9 Metabolism Endogenous Metabolite Cyanocobalamin inhibit Cobalamin Vitamin B-12 Vitamin B 12 Inhibitor inhibitor

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