Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hexamethylene bisacetamide inhibits BET Bromodomain Proteins.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 42.00 | |
50 mg | In stock | $ 66.00 | |
100 mg | In stock | $ 91.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Hexamethylene bisacetamide inhibits BET Bromodomain Proteins. |
In vitro | As expected of a BET inhibitor, HMBA displaced BET proteins from chromatin, caused massive transcriptional changes, and triggered cell-cycle arrest and apoptosis in Myc-induced B-cell lymphoma cells.?Furthermore, HMBA exerted anticancer effects in vivo in mouse models of Myc-driven B-cell lymphoma[1]. |
Molecular Weight | 200.28 |
Formula | C10H20N2O2 |
CAS No. | 3073-59-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (124.82 mM)
You can also refer to dose conversion for different animals. More
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Hexamethylene bisacetamide 3073-59-4 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor HMBA inhibit inhibitor