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N-Acetyl-L-glutamic acid

Catalog No. T5267 CAS 1188-37-0

Synonyms: Ac-L-Glu-OH, N-Acetylglutamic acid

N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.

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N-Acetyl-L-glutamic acid Chemical Structure

N-Acetyl-L-glutamic acid, CAS 1188-37-0

Pack Size	Availability	Price/USD	Quantity
500 mg	In stock	$ 41.00
1 mL * 10 mM (in DMSO)	In stock	$ 45.00

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Purity: 99.67%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Ac-L-Glu-OH, N-Acetylglutamic acid
Molecular Weight	189.17
Formula	C7H11NO5
CAS No.	1188-37-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 200 mM

References and Literature

1. Tavazzi B, et al. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism. Clin Biochem. 2005 Nov;38(11):997-1008.

Related compound libraries

This product is contained In the following compound libraries：

Microbial Natural Product Library Human Endogenous Metabolite Library Natural Product Library Gut Microbial Metabolite Library Human Endogenous Metabolite Compound Library Plus Human Metabolite Library RO5 Drug-like Natural Product Library Natural Product Library for HTS

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Keywords

N-Acetyl-L-glutamic acid 1188-37-0 Metabolism Others Endogenous Metabolite Inhibitor Ac-L-Glu-OH NAcetylLglutamic acid N Acetyl L glutamic acid inhibit N-Acetylglutamic acid inhibitor

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