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Deltamethrin
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Catalog No. T20754Cas No. 52918-63-5
Alias RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, Butoss
Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.
Deltamethrin
Copy Product Info🥰Excellent
Purity: 99.85%
Catalog No. T20754Alias RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, ButossCas No. 52918-63-5
Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $41 | In Stock | In Stock | |
| 200 mg | $57 | In Stock | In Stock | |
| 500 mg | $97 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $45 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.85%
Appearance:Solid
Color:White
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Product Introduction
Deltamethrin AI Summary
Deltamethrin displays a diverse array of bioactivities, indicating its potential for multiple therapeutic and pest control applications. It exhibits antagonistic activity against the interaction between CBF-beta and RUNX1, thyroid hormone receptor beta signaling, peroxisome proliferator-activated receptor gamma signaling, glucocorticoid receptor signaling, and retinoid X receptor alpha signaling. Conversely, it shows agonistic activity towards glucocorticoid receptor signaling, farnesoid X receptor signaling, and activating activity on nuclear factor-kappa B (NF-kB), antioxidant response element (ARE), and pregnane X receptor (both human and rat) signaling pathways. Additionally, Deltamethrin inhibits the binding or entry of Lassa and Marburg viruses into cells.
In terms of insecticidal properties, Deltamethrin is effective against various insect species, including second-instar larvae of Plutella xylostella, Culex pipiens pallens larvae, and adult Doru luteipes, with demonstrated efficacy at low concentrations. It also exhibits strong insecticidal activity against Mythimna separata and second-instar Spodoptera frugiperda, with potent toxic effects and high selectivity ratios for targeted pests. Furthermore, it is effective against Helicoverpa armigera with varying LD50 values and resistance factors, Bemisia tabaci with cross-resistance observed, Bactrocera oleae, Drosophila melanogaster, Nilaparvata lugens affecting multiple life cycle aspects, and Aedes aegypti mosquitoes displaying significant larvicidal activity.
The compound's broad-spectrum bioactivities suggest its utility in therapeutic interventions for diseases such as acute myeloid leukemia, viral infections, and various insect-related plant and public health issues..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, control of malaria and other vector-borne diseases. It is easily degradable. |
| Synonyms | RU-22974, RU 22974, K-Othrin, Esbecythrin, Decamethrin, Butoss |
| Molecular Weight | 505.20 |
| Formula | C22H19Br2NO3 |
| Cas No. | 52918-63-5 |
| Smiles | CC1(C)C(\C=C(/Br)Br)C1C(=O)OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1 |
| Relative Density. | 1.5214 g/cm3 (Estimated) |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (494.85 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Corn Oil: 2.5 mg/mL (4.95 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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