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Histamine

Name: Histamine
Brand: TargetMol
SKU: T0965
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0965Cas No. 51-45-6

Alias Ergamine

Histamine (Ergamine) is an amine derived by the enzymatic decarboxylation of histamine. Histamine is a potent stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and a neurotransmitter of central action.

Histamine

🥰Excellent

Purity: 96.63%

Catalog No. T0965Alias ErgamineCas No. 51-45-6

Pack Size	Price	Availability
50 mg	$36	In Stock
100 mg	$50	In Stock
200 mg	$68	In Stock

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Batch Information

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Purity:96.63%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Histamine (Ergamine) is an amine derived by the enzymatic decarboxylation of histamine. Histamine is a potent stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and a neurotransmitter of central action.
Targets&IC50	Sf9 cells:11 nM (EC50), HEK293 cells:13 nM (EC50), CHO cells:640 nM (EC50)
Synonyms	Ergamine

Chemical Properties

Molecular Weight	111.15
Formula	C₅H₉N₃
Cas No.	51-45-6
Smiles	NCCc1c[nH]cn1
Relative Density.	1.14g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 260 mg/mL (2339.18 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	8.9969 mL	44.9843 mL	89.9685 mL	449.8426 mL
5 mM	1.7994 mL	8.9969 mL	17.9937 mL	89.9685 mL
10 mM	0.8997 mL	4.4984 mL	8.9969 mL	44.9843 mL
20 mM	0.4498 mL	2.2492 mL	4.4984 mL	22.4921 mL
50 mM	0.1799 mL	0.8997 mL	1.7994 mL	8.9969 mL
100 mM	0.0900 mL	0.4498 mL	0.8997 mL	4.4984 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc