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L-Glutamic acid monosodium salt

Catalog No. T6871 CAS 142-47-2

Synonyms: Monosodium glutamate, Glutacyl, Glutavene, Ajinomoto, MSG

L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.

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L-Glutamic acid monosodium salt Chemical Structure

L-Glutamic acid monosodium salt, CAS 142-47-2

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50 mg	In stock	$ 33.00
100 mg	In stock	$ 46.00
500 mg	In stock	$ 61.00

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Biological Description

Chemical Properties

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Description	L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
In vitro	Monosodium glutamate(MSG) induces apoptosis in human B cells. It has a more potent apoptotic effect in na?ve B cells compared to memory B cell population[3]. Low doses of L-monosodium glutamate promote neuronal growth and differentiation in vitro[4].
In vivo	Daily monosodium glutamate(MSG) dietary consumption reduces pancreatic β-cell mass and enhances hemorrhages and fibrosis, but does not affect glucose homeostasis. High dietary MSG intake may exert a negative effect on the pancreas and such effect might become functionally significant in the presence or susceptibility to diabetes or NaCl. Parenteral MSG causes various changes in pancreatic islets such as hypertrophy, hyperplasia, decrease in acinar cells, α-cells and somatostatin cells and increase in fibrosis[1]. MSG may have some deleterious effects on the testes of Wistar rats and by extension may contribute to the causes of male infertility[2].
Cell Research	B cells are cultured with and with out increasing concentrations of MSG(1-100 mM) for 24 h. The number of early apoptotic cells and necrotic cells is determined using Annexin-V FITC/PI staining. (Only for Reference)

Synonyms	Monosodium glutamate, Glutacyl, Glutavene, Ajinomoto, MSG
Molecular Weight	169.11
Formula	C5H8NO4·Na
CAS No.	142-47-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: < 10 mM(< means unknown)

References and Literature

1. Boonnate P, et al. PLoS One. 2015, 10(6):e20131595. 2. Aisha D. Alalwani. Middle East Fertility Society Journal. 2014, 19(4):274-280. 3. Jovic Z, et al. Bratisl Lek Listy. 2009, 110(10):636-40. 4. Aruffo C, et al. Dev Neurosci. 1987, 9(4):228-39.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Anti-Cancer Drug Library Membrane Protein-targeted Compound Library Anti-Cancer Approved Drug Library Ion Channel Inhibitor Library FDA-Approved & Pharmacopeia Drug Library Ferroptosis Compound Library Natural Product Library for HTS Bioactive Compounds Library Max Food Additive Library

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Keywords

L-Glutamic acid monosodium salt 142-47-2 Apoptosis Membrane transporter/Ion channel Neuroscience Ferroptosis GluR iGluR L-Glutamic acid Endogenous Metabolite Inhibitor Monosodium glutamate inhibit LGlutamic acid monosodium salt Glutacyl Glutavene Ajinomoto L-Glutamic acid monosodium MSG Ionotropic glutamate receptors L Glutamic acid monosodium salt inhibitor

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