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Vitamin D3

Vitamin D3
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
Catalog No. T1135Cas No. 67-97-0
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Purity:99.82%
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Vitamin D3

Catalog No. T1135Cas No. 67-97-0

Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
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Pack SizePriceAvailabilityQuantity
1 g$33In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Product Introduction

Bioactivity
Description
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
Targets&IC50
H305F/H397Y mutant vitamin D receptor:300 nM(Kd)
AliasCholecalciferol, Colecalciferol
Chemical Properties
Molecular Weight384.64
FormulaC27H44O
Cas No.67-97-0
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (116.99 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5998 mL12.9992 mL25.9983 mL129.9917 mL
5 mM0.5200 mL2.5998 mL5.1997 mL25.9983 mL
10 mM0.2600 mL1.2999 mL2.5998 mL12.9992 mL
20 mM0.1300 mL0.6500 mL1.2999 mL6.4996 mL
50 mM0.0520 mL0.2600 mL0.5200 mL2.5998 mL
100 mM0.0260 mL0.1300 mL0.2600 mL1.2999 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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