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Dobutamine hydrochloride

Catalog No. T8149 CAS 49745-95-1

Synonyms: Dobutamine (hydrochloride)

Dobutamine (hydrochloride) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.

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Dobutamine hydrochloride, CAS 49745-95-1

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 97.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98%

Purity: 98.52%

Purity: 97.15%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Dobutamine (hydrochloride) is a catecholamine that acts as a β-adrenergic receptor agonist with potent positive inotropic effects.
In vivo	In wildtype mice increasing doses of dobutamine resulted in subsequent increase in the left ventricular function and heart rate acceleration, but significant inotropic, lusitropic, and chronotropic cardiac response was observed only after high doses of dobutamine.
Animal Research	Animal Model:Tgαq*44 mice (heart failure models). Dosage:0.15 mg/kg, 0.5 mg/kg as a low dose, 1.5 mg/kg, 5 mg/kg, 20 mg/kg as a high dose. Administration:Intraperitoneal injection

Synonyms	Dobutamine (hydrochloride)
Molecular Weight	337.84
Formula	C18H24ClNO3
CAS No.	49745-95-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

H2O: 20 mg/mL (59.20 mM), Need ultrasonic

DMSO: 33 mg/mL (97.68 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Tyrankiewicz U , et al. Characterization of the cardiac response to a low and high dose of dobutamine in the mouse model of dilated cardiomyopathy by MRI in vivo. J Magn Reson Imaging. 2013 Mar;37(3):669-77. 2. Vallet B, et al. Dobutamine: mechanisms of action and use in acute cardiovascular pathology. Ann Cardiol Angeiol (Paris). 1991 Jun;40(6):397-402.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Neurodegenerative Disease Compound Library Bioactive Compound Library Anti-Hypertension Compound Library Polyphenolic Natural Product Library FDA-Approved & Pharmacopeia Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Cancer Clinical Compound Library Adrenergic Receptor-Targeted Compound Library Endocrinology-Hormone Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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