445
52
60
2
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T80678 | (S)-AK-242 | (-)-Resatorvid,(S)-Resatorvid,AK-242 (S enantiomer),(-)-AK-242 | Others |
(S)-AK-242 ((S)-Resatorvid) is a cytokine inhibitor used in the treatment of heart disease, autoimmune disease, and inflammatory disease. | |||
T5490 | AK-7 | Sirtuin | |
AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM. | |||
T5618 | AK-1 | Sirtuin | |
AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 µM).that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells. | |||
T15815 | LY3295668 | AK-01 | Aurora Kinase |
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively. | |||
T26585 | AK301 | AK-301,AK 301 | Apoptosis , Microtubule Associated |
AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a ... | |||
T61802 | AK-778-XXMU | Others | |
AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas. | |||
T25009 | AK 275 | AK275,AK-275 | |
AK 275 is a calpain inhibitor that prevents degradation of cytoskeletal and myelin proteins in spinal cord in vitro. | |||
T25010 | AK-2-38 | AK -2-38,AK2-38 | |
AK-2-38 is a nifedipine analogue with potent smooth muscle calcium antagonist action and partial agonist effects on isolated guinea pig left atrium. | |||
T70469 | AK-42 | ||
AK-42 is a novel potent and specific inhibitor of CLC-2, displaying unprecedented selectivity over CLC-1, the closest CLC-2 homolog, and exhibiting no off-target engagement against a panel of 61 common channels, receptor... | |||
T29792 | AK-135 | ||
AK-135 is a derivative of 1,4-naphthoquinone (Menadione). AK-135 has been shown to restore the electron flow in defective respiratory chain (hypoxia or rotenone) systems more effectively than Menadione. | |||
T69046 | AK-106 | ||
AK-106, also known as AK106-001616, is a selective inhibitor of cytosolic phospholipase A2 (cPLA2) inhibitor. AK-106 has been shown to have analgesic activites similar to non-steroidal anti-inflammatory drugs (NSAIDs). | |||
T14307 | Aplaviroc | AK 602,GW 873140,GSK 873140 | HIV Protease , CCR |
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. | |||
T25011 | AK-295 | CX295,CX 295,AK295,CX-295 | |
AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain. | |||
T29804 | AK-Toxin II | ||
AK-Toxin II is a host-specific toxin to Japanese white pear. | |||
T21445 | Naphazoline | AK-Con,Naphcon-a,Clear Eyes,All Clear | Adrenergic Receptor |
Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. | |||
T74749 | AK-2292 | ||
AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC 50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and c... | |||
T73436 | AK-IN-1 | ||
AK-IN-1, a competitive inhibitor for adenosine (Ado) but not for ATP, demonstrates significant inhibition of AK activity, achieving 86%, 87%, and 89% at concentrations of 2, 4, and 10 µM, respectively. This compound show... | |||
T34508 | Sanazole | AK2123,AK-2123,AK 2123 | |
Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line. | |||
T13401 | Ziresovir | AK0529,RO-0529 | RSV |
Ziresovir (RO-0529) is a respiratory syncytial virus fusion protein (RSV F) inhibitor that inhibits RSV activity and can be used in the study of syncytial virus sensing. | |||
T80603 | Dresbuxelimab | AK-119 | CD73 |
Dresbuxelimab (AK-119), an IgG-κ monoclonal antibody, selectively targets CD73 and is commonly produced using a Chinese Hamster Ovary (CHO) cell expression system [1]. | |||
T26642 | Aplaviroc hydrochloride | AK602,AK 602,GW873140A,GW-873140,GW873140,AK-602,Aplaviroc HCl | |
Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In... | |||
T131727 | Compound AK-693/40962731 | ||
Compound AK-693/40962731 is a useful organic compound for research related to life sciences and the catalog number is T131727. | |||
T32699 | Levobunolol | Levobunololum,Liquifilm,AK-Beta,Betegan | |
Levobunolol is a nonselective beta-blocker. It is used topically to treat glaucoma. | |||
T8408 | GKT136901 | AK120765 | NADPH-oxidase , NADPH |
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite | |||
T69243 | AK963 | ||
AK963, also known as 40708899, is a potent PAK1 (p21-activated kinase 1) inhibitor, which suppresses the proliferation of human gastric cancer cells significantly by downregulation of PAK1-NFκB-CyclinB1 pathway. | |||
T3076 | GLPG0634 analog | GLPG0634 analogue | Tyrosine Kinases , JAK |
GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively. | |||
T70468 | MK-8666 | ||
MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also known as free fatty acid (FFA) receptor 1 modulates fatty acid-induced insulin secretion in pancrea... | |||
T5508 | PF-AKT400 | AKT protein kinase inhibitor | Akt |
PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt. | |||
TP1093 | TAK-448 acetate | TAK-448 acetate (1234319-68-6 Free base),MVT-602 acetate | Kisspeptin |
TAK-448 acetate (MVT-602 acetate) is a small molecule KISS1R agonist, a synthetic peptide similar to kisspeptin.TAK-448 acetate has antitumor activity, inhibits the proliferation of VCaP cells, and can be used in prostat... | |||
T6358 | 1-Azakenpaullone | azakenpaullone | GSK-3 |
1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25. | |||
T76784 | Tildrakizumab | MK 3222,SCH 900222 | IL Receptor |
Tildrakizumab (SCH 900222) is a potent humanized monoclonal antibody against IL-23 (p19 subunit). Tildrakizumab targets single-stranded IL-23 with a Kd value of 136 pM. Tildrakizumab can be used to study psoriasis and ps... | |||
TQ0150 | Levcromakalim | (-)-Cromakalim,BRL 38227 | Potassium Channel |
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel. | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T9529 | TAK-020 | BTK | |
TAK-020 is a potent covalent inhibitor of Btk with potential antitumor activity for the study of rheumatoid arthritis and immune-related diseases. | |||
T7200 | TAK-960 | PLK | |
TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively. | |||
T16975 | TAK-593 | VEGFR , PDGFR | |
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively). | |||
T27624 | Iptakalim Hydrochloride | Potassium Channel , AChR | |
Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2... | |||
T77718 | FAK-IN-10 | FAK | |
FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively. | |||
T6150 | TAK-715 | p38 MAPK , Casein Kinase , JNK | |
TAK-715 is a p38 MAPK inhibitor for p38α. | |||
T26174 | SAK3 | SAK 3,SAK-3 | Calcium Channel , AChR |
SAK3 is a novel modulator of nAChR activity that enhances T-type voltage-gated Ca2+ channel (T-VGCC) activity, and has potentiating effects on both Cav3.1 and Cav3.3 T-type Ca2+ channel currents.SAK3 is neuroprotective a... | |||
T7406 | AKR1C3-IN-1 | NADPH | |
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM). | |||
T67754 | JAK3-IN-14 | FLT | |
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. | |||
T3042 | JAK2 Inhibitor V | JAK2 Inhibitor V Z3,Z3 | JAK |
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner. | |||
T15201 | MAK683 | Histone Methyltransferase | |
MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay). | |||
T78607 | JAK-STAT-IN-1 | JAK , STAT | |
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases. | |||
T38562 | AKN-028 | FLT | |
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation. | |||
T28950 | Terlakiren | CP 80794,CP-80,794 | RAAS |
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. | |||
T63388 | IRAK4-IN-8 | IRAK | |
IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation. | |||
TP1496L | P5 Ligand for Dnak and DnaJ acetate | p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base) | HSP |
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40). | |||
T6039 | TAK-285 | TAK285,TAK 285 | EGFR , MEK , HER , Aurora Kinase |
TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T29795 | Akagerinelactone | ||
Akagerinelactone is a biochemical. | |||
TWS1977 | Kamebakaurin | Kamebakaurine | NF-κB |
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression... | |||
TN2043 | Pasakbumin B | 13-alpha-(21)-Epoxyeurycomanone | Others |
Pasakbumin B (13-alpha-(21)-Epoxyeurycomanone) is a bioactive compound from Eurycoma longifolia Jack. | |||
T5813 | BYAKANGELICIN | Reductase | |
BYAKANGELICIN,a main furanocoumarin constituent isolated and characterized as an aldose reductase inhibitor,and is effective for the treatment of sugar cataracts and diabetic neuropathy and hence might be useful as a lea... | |||
T3801 | (Rac)-Byakangelicin | Bjacangelicin,Bjakangelicin,Biacangelicin,7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-,Byakangelicin | Others |
(Rac)-Byakangelicin (7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-) is an antineoplastic agent. | |||
T24417 | Yakuchinone A | Yakuchinone-A | Others |
Yakuchinone A (Yakuchinone-A) is a natural product isolated from Alpinia oxyphylla Miquel. Yakuchinone-A has strong inhibitory effects on the synthesis of prostaglandins and leukotrienes in vitro. Yakuchinone A inhibits ... | |||
TQ0264 | Nigakinone | Others | |
Nigakinone, isolated from Kumu, is an alkaloid with the pharmacological activity. | |||
TN1800 | Isosakuranin | Others | |
Isosakuranin is a product from Paliurus ramosissimus. | |||
T3S1960 | Kakuol | Antifungal | |
1. Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 5 microg ml(-1) and 3 microg ml(-1), respectively. 2. kakuol ... | |||
T5S1413 | Nodakenetin | Prangeferol,(-)-Prangeferol,Nodakenitin | Others |
1. Nodakenetin ((-)-Prangeferol) has clinical efficacy. | |||
T3400 | Bakuchiol | p38 MAPK , DNA/RNA Synthesis , Autophagy | |
Bakuchiol possesses anti-tumor,and anti-helmenthic properties. It has cytotoxic activity, mainly due to its DNA polymerase1 inhibiting activity. Bakuchiol has anti-bacterial activity against oral pathogens, has great pot... | |||
TN1927 | Methyl Kakuol | 1-(6-methoxy-1,3-benzodioxol-5-yl)propan-1-one | TRP/TRPV Channel |
Methyl Kakuol is an agonist of TRPA1 with an EC50 of 0.27 µM and can be used in studies about acting as an active ingredient in MBST constituent Asiasari Radix. | |||
T3872 | Nodakenin | (+)-Marmesinin | AChE |
Nodakenin ((+)-Marmesinin) is a compound with anti-allergic and anti-inflammatory activities. | |||
TN1829 | Kakkalide | Dehydrogenase | |
Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects. | |||
TN1839 | Kumatakenin | Jaranol,Kaempferol 3,7-O-dimethyl ether | Apoptosis , Anti-infection |
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL. | |||
T6S0077 | Byakangelicol | COX | |
1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expr... | |||
T5S0229 | Isosakuranetin | 4'-Methylnaringenin | Others |
1. Isosakuranetin (4'-Methylnaringenin) has cytotoxic and fungicide properties. 2. Isosakuranetin produces significant decrease in blood pressure. 3. Isosakuranetin significantly reduces the sensitivity of mice to noxiou... | |||
TN1126 | Sakuranetin | VEGFR , NF-κB , PPAR , Antifungal | |
Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects | |||
T5S1569 | AKBA | 3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid | Others , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite |
AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2. | |||
T40440 | Isobyakangelicol | Isobyakangelicol,Anhydrobyakangelicin | |
Isobyakangelicol, a coumarin compound present in Angelica dahurica roots, exhibits inhibitory effects on the growth of HeLa and HepG2 cells, with IC50 values of 70.04 μM and 17.97 μM, respectively. | |||
T40733 | Kakkanin | ||
Kakkanin, a compound extracted from the roots of O. henryi, holds potential for anti-inflammatory research applications. | |||
T37471 | Makisterone A | ||
Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity. | |||
TN3486 | Bakkenolide IIIa | ERK , BCL , IκB/IKK , NF-κB , Akt | |
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB signaling. | |||
TN2568 | 10-Hydroxydihydroperaksine | Others | |
10-Hydroxydihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2568 and the CAS number is 451478-47-0. 10-Hydroxydihydroperaksine can be used as a reference standard. | |||
T13537 | Akuammiline | Others | |
Akuammiline is isolated from the seeds of Picralima klaineana. | |||
TN3485 | Bakkenolide III | Others | |
Bakkenolide III may have cytotoxicity. | |||
TN2325 | (Z)-Akuammidine | Others | |
(Z)-Akuammidine is a natural product | |||
TN2945 | 3-Hydroxybakuchiol | ATPase , Caspase | |
3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, th... | |||
TN4632 | Neobyakangelicol | Others | |
Neobyakangelicol has anti-lipolytic hormones effects, it can strongly inhibit insulin- stimulated lipogenesis. | |||
T81013 | Tert-OMe-byakangelicin | ||
Tert-OMe-byakangelicin is a coumarin known to potentiate adrenaline-induced lipolysis and impede insulin-mediated triglyceride synthesis from glucose in adipocytes [1]. | |||
T11712 | Jasplakinolide | Jaspamide,NSC-613009 | Microtubule Associated , Antifungal |
Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin... | |||
TN3483 | Bakkenolide D | IL Receptor , Histamine Receptor | |
Bakkenolide D has anti-allergic effect, it and bakkenolide D demonstrates inhibitory effect on the trachea contraction induced by histamine in vitro, they have obvious anti-histamine activities. | |||
T21030 | 3α-Akebonoic Acid | 3αAkebonoic acid,3α Akebonoic acid | |
3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity. | |||
TN3368 | Akuammigine | Opioid Receptor , Adrenergic Receptor | |
Akuammigine has in vitro antimalarial activity. Akuammigine competitively antagonizes the effect of noradrenaline on postsynaptic alpha-adrenoceptors, yielding pA2 values of 4.68. Akuammidine also shows a preference for ... | |||
T81153 | Sitakisogenin | ||
Sure, please provide the description of the chemical compound you'd like to be rewritten. | |||
T29794 | Akagerine | ||
Akagerine is derived from the root bark of South American Strychnos. | |||
T80778 | Weak Hepatoprotective agent-1 | ||
Compound 11, labeled as a weak Hepatoprotective agent-1, is a naturally occurring substance extracted from the fruits of Arctium lappa L. It demonstrates modest hepatoprotective effects when applied at a concentration of... | |||
T19932 | Gentiakochianin | BRN1351024,BRN 1351024,NSC 289490,BRN-1351024 | |
Gentiakochianin is an agent of biochemical. | |||
TN6473 | 6'-Feruloylnodakenin | ||
6'-Feruloylnodakenin is a natural product for research related to life sciences. The catalog number is TN6473 and the CAS number is 131623-14-8. | |||
TN2562 | 1-Oxobakkenolide S | Others | |
1-Oxobakkenolide S is a natural product for research related to life sciences. The catalog number is TN2562 and the CAS number is 18456-02-5. | |||
TN2051 | Perakine | Others | |
Perakine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2051 and the CAS number is 4382-56-3. Perakine can be used as a reference standard. | |||
TN4385 | Ketohakonanol | Others | |
Ketohakonanol is a natural product for research related to life sciences. The catalog number is TN4385 and the CAS number is 18004-20-1. | |||
TN3484 | Bakkenolide Db | Others | |
Bakkenolide Db may have cytotoxicity. | |||
T81657 | Nodakenetin-Glucose-malonic acid | ||
Nodakenetin-Glucose-malonic acid is a natural compound [1]. | |||
T79944 | 2-O-Sinapoyl makisterone A | COX | |
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively suppressing the expression of COX-2 protein [1]. | |||
TN6030 | Peraksine | ||
Peraksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN6030 and the CAS number is 15527-80-7. Peraksine can be used as a reference standard. | |||
T2S0606 | Bakkenolide A | IL Receptor , IκB/IKK , GSK-3 , TNF , Akt , Caspase , PI3K , HDAC | |
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways. | |||
TN3367 | Akuammidine | Opioid Receptor | |
Akuammidine shows anti-inflammatory and anti-asthmatic properties, it has opioid analgesic activity, it shows a preference for mu-opioid binding sites with Ki values of 0.6, 2.4 and 8.6 microM at mu-, delta- and kappa-op... | |||
T38806 | Pasakbumin D | 13β,21-Dihydroxyeurycomanone | |
Pasakbumin D is a quassinoid and can be used for the research of cancer. | |||
TN3860 | Dihydroperaksine | Others | |
Dihydroperaksine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN3860 and the CAS number is 16100-84-8. Dihydroperaksine can be used as a reference standard. | |||
------------------------ More ------------------------ |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03088 | Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) | Penaeus monodon | E. coli |
N/A. Arginine kinase/AK Protein, Penaeus monodon, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.0 kDa and the accession number is C7E3T4. | |||
TMPY-04473 | ADK Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme ade... | |||
TMPH-03503 | Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) | Shigella flexneri | E. coli |
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexn... | |||
TMPY-04469 | AK3L1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AK3L1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 53 kDa and the accession number is P27144-1. | |||
TMPY-04755 | AK3L1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
AK3L1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 25.3 kDa and the accession number is P27144-1. | |||
TMPY-04483 | IRAK4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4... | |||
TMPY-04552 | AKT1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ... | |||
TMPY-04387 | AKT2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AKT (AK mouse plus Transforming or Thymoma) is a frequent oncogene expressed in most tissues which includes three isoforms AKT1, AKT2, and AKT3. Hyperactivation of AKT signaling is a central key in many human cancer prog... | |||
TMPH-02092 | PAK5 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
N/A. PAK5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q8TB93. | |||
TMPY-04574 | AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) | Mouse | Baculovirus Insect Cells |
AKT3 Protein, Mouse, Recombinant (aa 106-479, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 71 kDa and the accession number is Q9WUA6-1. | |||
TMPK-00696 | PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II) | Human | Baculovirus Insect Cells |
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-... | |||
TMPY-05878 | Influenza A H1N2 (A/swine/Miyazaki/1/2006) Hemagglutinin/HA Protein (His) | H1N2 | HEK293 Cells |
Influenza A H1N2 (A/swine/Miyazaki/1/2006) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.4 kDa and the accession number is B3IYD3. | |||
TMPH-02272 | JAK1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-03701 | Vespakinin-M Protein, Vespa mandarinia, Recombinant (His & KSI) | Vespa mandarinia | E. coli |
Bradykinins are a potent but short-lived agent of arteriolar dilation and increased capillary permeability. May target bradykinin receptors (BDKRB). May cause hypotension. Vespakinin-M Protein, Vespa mandarinia, Recombin... | |||
TMPH-00059 | Major allergen Ani s 1 Protein, Anisakis simplex, Recombinant (His & Myc) | Anisakis simplex | E. coli |
Major allergen Ani s 1 Protein, Anisakis simplex, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.3 kDa and the accession number is Q7Z1... | |||
TMPH-03076 | Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) | Pacifastacus leniusculus | E. coli |
Cytokine directly involved in hematopoiesis. Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16... | |||
TMPH-02382 | Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO) | MARV | E. coli |
Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 ... | |||
TMPH-03457 | CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) | Saccharomyces cerevisiae | E. coli |
CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P43568. | |||
TMPY-03374 | TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) | Human,Cynomolgus | HEK293 Cells |
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.8 kDa and the accession number is F7HGN4. | |||
TMPH-02385 | Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc) | MARV | E. coli |
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary ... | |||
TMPY-06782 | Influenza A H5N8 (A/Astrakhan/3212/2020) Hemagglutinin/HA1 Protein (His) | H5N8 | Baculovirus Insect Cells |
Influenza A H5N8 (A/Astrakhan/3212/2020) Hemagglutinin/HA1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 38.7 kDa. | |||
TMPJ-01312 | TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it... | |||
TMPH-00593 | DnaK Protein, E. coli, Recombinant (Yeast, His) | E. coli | P. pastoris (Yeast) |
Acts as a chaperone. | |||
TMPK-00727 | TNFSF12/TWEAK Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a well known multifunctional cytokine extensively distributed in cell types and tissues. Accumulating evidence has shown that TWEAK binding to the receptor ... | |||
TMPY-02438 | AKR1B1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest... | |||
TMPY-06784 | Influenza A H5N8 (A/Astrakhan/3212/2020) Hemagglutinin/HA Protein (His) | H5N8 | Baculovirus Insect Cells |
Influenza A H5N8 (A/Astrakhan/3212/2020) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 64.16 kDa. | |||
TMPY-03497 | AKR1C2 Protein, Human, Recombinant (His) | Human | E. coli |
AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using ... | |||
TMPH-02273 | JAK1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-02738 | IRAK3 Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors. Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by ... | |||
TMPY-05898 | Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) | H3N2 | HEK293 Cells |
Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is A0A077KEB1. | |||
TMPY-03302 | TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
TWEAK/TNFSF12 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is Q6AYC1. | |||
TMPH-02274 | JAK2 Protein, Human, Recombinant (His) | Human | E. coli |
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto... | |||
TMPY-04670 | Influenza A H14N5 (A/mallard/Astrakhan/263/1982) Hemagglutinin/HA Protein (His) | H14N5 | Baculovirus Insect Cells |
Influenza A H14N5 (A/mallard/Astrakhan/263/1982) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.6 kDa and the accession number is P26136. | |||
TMPY-04397 | PAK-3 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are si... | |||
TMPH-02739 | IRAK3 Protein, Mouse, Recombinant (E. coli, His & Myc) | Mouse | E. coli |
IRAK3 Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli. | |||
TMPH-02384 | Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc) | MARV | E. coli |
Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is P3526... | |||
TMPH-02635 | EEF1AKMT2 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'. EEF1AKMT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted... | |||
TMPJ-00207 | AKR1C2 Protein, Human, Recombinant | Human | E. coli |
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation o... | |||
TMPH-00592 | DnaK Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Acts as a chaperone. | |||
TMPY-04425 | PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated... | |||
TMPY-04553 | AKT3 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
AKT3 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 81 kDa and the accession number is Q9Y243-1. | |||
TMPY-02461 | AKR1A1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehy... | |||
TMPH-02961 | JAK1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but ... | |||
TMPH-02498 | AKR1C3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with... | |||
TMPH-02091 | PAK1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
PAK1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00400 | DHAK Protein, Citrobacter freundii, Recombinant (His & SUMO) | Citrobacter freundii | E. coli |
Catalyzes the phosphorylation of dihydroxyacetone. DHAK Protein, Citrobacter freundii, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.9 kDa ... | |||
TMPH-01556 | EIF2AK2 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
EIF2AK2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 64.0 kDa and the accession number is P19525. | |||
TMPH-01417 | AK3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
AK3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00044 | RuvC Protein, Akkermansia muciniphila, Recombinant (His & Myc) | Akkermansia muciniphila | E. coli |
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junct... | |||
TMPY-00481 | AKR1C4 Protein, Human, Recombinant (His) | Human | E. coli |
Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L3700 | JAK-STAT Compound Library | 252 compounds | |
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L1300 | PI3K-AKT-mTOR Compound Library | 420 compounds | |
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; |