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Search Result

Search Results for " nsc "

Targets

Reverse Transcriptase Others

1068

Compounds

254

Natural Products

4

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T22383 NSC 31152 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione,NSC 102533 Others
NSC-31152 (5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione) is a bioactive chemical.
T6342 NSC 23766 trihydrochloride Rac1 Inhibitor,NSC 23766 Apoptosis , Rho , Ras
NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 μM); no inhibitory for the closely related targets, RhoA or Cdc42.
T9168 NSC 617145 NSC617145,NSC-617145 DNA/RNA Synthesis
NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.
T9398 NSC 73150 NSC 97967 Others
6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a...
T4631 NSC 4810 Others
NSC 4810 is an amide bioactive compound that has been used as a substrate for cytochrome P450 enzymes in vivo and as a substrate for acetylcholinesterase in vitro.
T4174 NSC 191412 Others
NSC 191412 interacts with a variety of enzymes and receptors, including acetylcholinesterase and receptors for the neurotransmitter dopamine, and is an agonist or activator of these enzymes and receptors.
T16349 NSC-60339 Others , Antibacterial
NSC-60339 is an inhibitor of efflux pump, and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.
T7078 NSC 95397 Apoptosis , Phosphatase
NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).
T5211 NSC 185058 NSC185058 Cysteine Protease , Autophagy
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.
T4178 NSC 80538 Others
NSC 80538 is an inhibitor of MEK Kinase PB1 Domains in multiplex HTS assays.
T22382 NSC 31150 Antioxidant , Antibiotic , PPAR
NSC 31150 is a potential PPAR agonist with antibacterial, antidiabetic and antioxidant activities and may be used to study cancer and bacterial infections.
T2031 NSC-41589 NSC41589 Others
NSC-41589 is N-[2-(methylsulfanyl) phenyl]acetamide.
T9949 NSC 370284 STAT
NSC 370284 is a small molecule that directly binds to and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
T16350 NSC-87877 Apoptosis , Phosphatase
NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26).
T1891 NSC 405020 MMP
NSC 405020 is a noncatalytic inhibitor of MT1-MMP.
T12257 NSC 146109 hydrochloride Apoptosis , Others
NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
T4630 NSC 404988 Others
NSC 404988 is a benzamide-based bioactive compound used in the synthesis of compounds and the preparation of drugs, and has also been used in the study of drug metabolism and the analysis of metabolites in biological sys...
T7691 NSC 3852 HDAC
NSC 3852 is a potent inhibitor of histone deacetylase.
T21578 NSC 66811 Mdm2
NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53...
T3572 NSC 15364 1,3-Bis(4-aminophenyl)urea,NSC15364 Apoptosis , Others , VDAC
NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.
T6908 NSC 228155 NSC228155 EGFR , Epigenetic Reader Domain , DNA/RNA Synthesis , Histone Acetyltransferase
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
T19759 NSC-226572 Methyiin, pyrolyzate Others
NSC-226572 (Methyiin, pyrolyzate) is a synthetic analog of alliin found in cruciferous vegetables including cabbage, turnip, cauliflower, and kale. NSC-226572 is converted through alliinase activity into a volatile thios...
T8573 NSC 65809 3-[(2,3-dichlorophenyl)methylene]carbazamidine,Raphin1 Phosphatase
NSC-65809 (Raphin1) is a selective inhibitor of R15B.
T22387 NSC 55655 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione Others
NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C...
T4184 NSC 409012 5-(4-iodobenzylidene)rhodanine Others
NSC-409012 (5-(4-iodobenzylidene)rhodanine) is an active compound that has been found to have a variety of biochemical and physiological effects, including regulation of gene expression, cell proliferation and apoptosis....
T6911 NSC-87877 disodium NSC87877 Apoptosis , Phosphatase
NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduce...
T4632 NSC 6038 4-chloro-N,N-dipropylbenzamide,4-Chloro-N,N-di-n-propylbenzaMide Others
NSC-6038 (4-chloro-N,N-dipropylbenzamide) is a benzamide-based bioactive compound with a wide range of biological activities and has been shown to possess anti-inflammatory, antioxidant and anti-angiogenic activities, an...
T60558 NSC 694623 Histone Acetyltransferase
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with IC50 of 15.9 μM against recombinant HAT p300/CBP associated factor (PCAF). NSC 694623 shows anti-proliferative activity against some cancer cells, whi...
T83636L NSC 122393 3,4,5,6-Tetrabromofluorescein
NSC 122393 is a fluorescent dye that inhibits the interaction between Bax and Bcl-X and induces apoptosis in Bcl-X overexpressing breast cancer cells.
T3571 SU5201 NSC 247030 Others , Interleukin
SU5201 (NSC 247030) is a biochemical.
T3570 SU4312 SU 4312,NSC 86429 VEGFR , PDGFR
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotox...
T28208 NSC-636819 NSC 636819
NSC-636819 is a novel inhibitor of KDM4A/KDM4B.
T24553 NSC-639829 NSC 639829
NSC-639829 is a tubulin polymerization inhibitor that acts by demonstrating potent antitumor activities against several cancer cell lines.
T25888 NSC-670224 NSC 670224
NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts ...
T33742 NSC 184692 NSC-184692,NSC184692
NSC 184692 is a aminopterin-derivative.
T28213 NSC-77053 NSC 77053,NSC77053
NSC-77053 is a BoNT/E inhibitor.
T33744 NSC 30705 NSC-30705,NSC30705
NSC 30705 is a biochemical.
T33738 NSC 144698 NSC-144698,NSC144698
NSC 144698 is a bioactive chemical.
T33739 NSC 152737 NSC-152737,NSC152737
NSC 152737 is a therapeutic agent.
T33746 NSC 660028 NSC660028,NSC-660028
NSC 660028 is a novel γ-lactone ring modified arylamino etoposide analogram with strong antitumor activity as an inhibitor of human DNA topoisomerase II.
T28204 NSC-176377 NSC 176377
NSC-176377 is a non-nucleoside reverse transcriptase inhibitor.
T25889 NSC-689857 NSC 689857,NSC689857
NSC-689857 is an inhibitor that acts in the Skp2-Cks1 protein-protein interaction and p27Kip1 ubiquitination in vitro.
T38414 NSC 80467
NSC 80467, a selective DNA damaging agent, functions by inhibiting survivin. Specifically, it preferentially targets DNA synthesis, leading to the induction of two distinct markers of DNA damage, namely γH2AX and pKAP1.
T33741 NSC 174121 NSC-174121,NSC174121
NSC 174121 is a methotrexate derivative.
T33745 NSC 341077 NSC-341077,NSC341077
NSC 341077 is a bioactive chemical.
T33747 NSC 695574 NSC-695574,NSC695574
NSC 695574 is a bioactive chemical.
T33748 NSC 77152 NSC77152,NSC-77152
NSC 77152 is a bioactive chemical.
T36292 NSC 12
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate ...
T40848 NSC 23766
NSC 23766, a cell-permeable compound, is a reversible and specific inhibitor of Rac GTPase. Its primary application lies in the field of cancer treatment.
T69123 NSC-2488
NSC-2488 is a novel Rho-Kinase-II Inhibitor with Vasodilatory Activity.

Compounds

NSC 31152
T22383
Synonym: 5-(4-Chloro-benzylidene)-thiazolidine-2,4-dione,NSC 102533
Target: Others
NSC 23766 trihydrochloride
T6342
Synonym: Rac1 Inhibitor,NSC 23766
Target: Apoptosis, Rho, Ras
NSC 617145
T9168
Synonym: NSC617145,NSC-617145
Target: DNA/RNA Synthesis
NSC 73150
T9398
Synonym: NSC 97967
Target: Others
NSC 4810
T4631
Synonym:
Target: Others
NSC 191412
T4174
Synonym:
Target: Others
NSC-60339
T16349
Synonym:
Target: Others, Antibacterial
NSC 95397
T7078
Synonym:
Target: Apoptosis, Phosphatase
NSC 185058
T5211
Synonym: NSC185058
Target: Cysteine Protease, Autophagy
NSC 80538
T4178
Synonym:
Target: Others
NSC 31150
T22382
Synonym:
Target: Antioxidant, Antibiotic, PPAR
NSC-41589
T2031
Synonym: NSC41589
Target: Others
NSC 370284
T9949
Synonym:
Target: STAT
NSC-87877
T16350
Synonym:
Target: Apoptosis, Phosphatase
NSC 405020
T1891
Synonym:
Target: MMP
NSC 146109 hydrochloride
T12257
Synonym:
Target: Apoptosis, Others
NSC 404988
T4630
Synonym:
Target: Others
NSC 3852
T7691
Synonym:
Target: HDAC
NSC 66811
T21578
Synonym:
Target: Mdm2
NSC 15364
T3572
Synonym: 1,3-Bis(4-aminophenyl)urea,NSC15364
Target: Apoptosis, Others, VDAC
NSC 228155
T6908
Synonym: NSC228155
Target: EGFR, Epigenetic Reader Domain, DNA/RNA Synthesis, Histone Acetyltransferase
NSC-226572
T19759
Synonym: Methyiin, pyrolyzate
Target: Others
NSC 65809
T8573
Synonym: 3-[(2,3-dichlorophenyl)methylene]carbazamidine,Raphin1
Target: Phosphatase
NSC 55655
T22387
Synonym: 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione
Target: Others
NSC 409012
T4184
Synonym: 5-(4-iodobenzylidene)rhodanine
Target: Others
NSC-87877 disodium
T6911
Synonym: NSC87877
Target: Apoptosis, Phosphatase
NSC 6038
T4632
Synonym: 4-chloro-N,N-dipropylbenzamide,4-Chloro-N,N-di-n-propylbenzaMide
Target: Others
NSC 694623
T60558
Synonym:
Target: Histone Acetyltransferase
NSC 122393
T83636L
Synonym: 3,4,5,6-Tetrabromofluorescein
Target:
SU5201
T3571
Synonym: NSC 247030
Target: Others, Interleukin
SU4312
T3570
Synonym: SU 4312,NSC 86429
Target: VEGFR, PDGFR
NSC-636819
T28208
Synonym: NSC 636819
Target:
NSC-639829
T24553
Synonym: NSC 639829
Target:
NSC-670224
T25888
Synonym: NSC 670224
Target:
NSC 184692
T33742
Synonym: NSC-184692,NSC184692
Target:
NSC-77053
T28213
Synonym: NSC 77053,NSC77053
Target:
NSC 30705
T33744
Synonym: NSC-30705,NSC30705
Target:
NSC 144698
T33738
Synonym: NSC-144698,NSC144698
Target:
NSC 152737
T33739
Synonym: NSC-152737,NSC152737
Target:
NSC 660028
T33746
Synonym: NSC660028,NSC-660028
Target:
NSC-176377
T28204
Synonym: NSC 176377
Target:
NSC-689857
T25889
Synonym: NSC 689857,NSC689857
Target:
NSC 80467
T38414
Synonym:
Target:
NSC 174121
T33741
Synonym: NSC-174121,NSC174121
Target:
NSC 341077
T33745
Synonym: NSC-341077,NSC341077
Target:
NSC 695574
T33747
Synonym: NSC-695574,NSC695574
Target:
NSC 77152
T33748
Synonym: NSC77152,NSC-77152
Target:
NSC 12
T36292
Synonym:
Target:
NSC 23766
T40848
Synonym:
Target:
NSC-2488
T69123
Synonym:
Target:
1 2 3 4 5 ... 22
Cat No. Product Name Synonyms Targets
T4987 NSC 42196 Calcium α-D-heptagluconate hydrate,Calcium glucoheptonate Others , Endogenous Metabolite
NSC 42196 (Calcium glucoheptonate) is the calcium salt of (2xi)-D-gluco-heptonic acid. NSC 42196 is used as a calcium supplement for treatment of hypocalcemia.
T25114 Ascaridole NSC-406266,NSC 406266,NSC406266 Parasite
Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.
T17214 Valencene NSC 148969,NSC-148969,NSC148969 Others , Antioxidant , NF-κB
Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, an...
T20250 Phenyl salicylate NSC-33406,NSC 33406,NSC33406 Others
Phenyl salicylate (NSC-33406) is a chemical substance. It is synthesized by heating salicylic acid with phenol.
T15544 Iberin NSC 321801 Endogenous Metabolite
Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.
T64343 3-Methylcarbazole NSC 10154 Others
3-Methylcarbazole (NSC-10154) is an carbazole alkaloid compound with anticancer effects.
T32832 Lobelanidine NSC-95097,8,10-Diphenyllobelidiol,NSC 95097,NSC95097 AChR
Lobelanidine (8,10-Diphenyllobelidiol), which can be extracted from the above-ground parts of Lobelia chinensis Lour and Lobelia tupa, is an analogue of lobeline and shows a moderate affinity for nAChR.
T20041 2'-Deoxyadenosine NSC-141848,NSC141848,NSC 141848 Endogenous Metabolite
2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.
T16791 Rottlerin Mallotoxin,NSC 56346,NSC 94525 CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
TN2063 Physalin B NSC-287088 Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel...
TN1466 Canthin-6-one NSC 103003 Antifungal
Canthin-6-one (NSC 103003)is an alkaloid isolated from Allium neapolitanum with antibacterial activity and inhibitory effect against Mycobacterium tuberculosis.
T0722 Ursolic acid Malol,Urson,NSC 167406,NSC-4060,Prunol Endogenous Metabolite , Autophagy
Ursolic acid (Prunol)(Bungeolic acid), a natural pentacyclic triterpenoid carboxylic acid, shows anti-tumor effects.
T20550 Thiobarbituric acid NSC4733,NSC 4733,NSC-4733 Antibacterial
Thiobarbituric acid (NSC-4733) has Antibacterial Activity.
T20091 Stearamide Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Stearamide(Stearic acid amide) is a primary fatty acid amide that is cytotoxic and fish toxic and can be used to increase the properties of nanoparticles.
TP1072 Valinomycin NSC 122023 Apoptosis , PTEN , Antibacterial , Antibiotic , Autophagy
Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.
T1067 Amphotericin B NSC 527017 Antibiotic , Antifungal
Amphotericin B (NSC-527017) is a polyene antifungal agent with broad-spectrum activity against many fungal species. Amphotericin B irreversibly binds to ergosterol and disrupts the integrity of cell membranes, resulting ...
T20312 3-Phenylpropanal NSC-9271,Phenylpropyl aldehyde,NSC9271,NSC 9271 Others
3-Phenylpropanal (Phenylpropyl aldehyde) is a RIFM flavor ingredient and can be used to make perfume.3-Phenylpropanal is the main ingredient in acaricides.3-Phenylpropanal can be used as a fly attractant.3-Phenylpropanal...
T19931 Gentisein NSC 329491,NSC329491,NSC-329491 Serotonin Transporter
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].
TC0025 Testosterone acetate NSC523836,NSC-523836,NSC 523836 Others
Testosterone acetate (NSC-523836) is a hormone with in vitro antitumor activity.
T20699 Daunomycinone Daunomycinon,Leukaemomycinone C,NSC 109351,NSC-109351,NSC109351 Antibiotic
Daunomycinone (NSC-109351) is a glycan of daunomycin, which belongs to the antibiotic class and is a representative glycan of tumour-inhibiting anthracyclines, used in the treatment of cancer and leukaemia.
T19962 Xyloidone NSC-106453,NSC106453,Dehydro-α-lapachone,NSC 106453,Dehydrolapachone,NSC 629748 Antifungal
Xyloidone (NSC-106453) exhibits antifungal activity and completely inhibits the mycelial growth of B. cinerea, Colletotrichum acutatum Simmonds, Colletotrichum gloeosporioides Simmonds, M. grisea, and Pythium ultimum Tro...
T2838 Naringenin Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875 P450 , Influenza Virus , Reactive Oxygen Species , Endogenous Metabolite , PPAR
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. T...
T21351 Maytansine NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine Microtubule Associated , Antibiotic
Maytansine (NSC-153858), an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
T32291 Jineol NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081 Others
Jineol (NSC-694081) is a quinoline alkaloid from Scolopendra subspinipes. Jineol shows cytotoxic activity against the growth of human tumor cell lines in vitro.
T6343 Geldanamycin NSC 122750 HSP , Influenza Virus , Tyrosine Kinases , Antibacterial , Antibiotic
Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
T2S0265 Robinin NSC 9222 TLR
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR...
T20225 Dicentrine, (-)- L-Dicentrine,NSC 251699,NSC251699,NSC-251699 Others
Dicentrine, (-)- (NSC-251699) is an aporphinic alkaloid found in several plant species, which showed significant antinociceptive activity in an acute model of visceral pain in mice.
T4088 Thymoquinone NSC 2228,Thymoquinon BCL
Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects.
T17303 α-Cyclodextrin Alfadex,NSC269470,NSC 269470,NSC-269470 Others
α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
T20488 4-Isopropylbenzoic acid NSC1907,NSC-1907,NSC 1907,Cumic acid Antifungal
4-Isopropylbenzoic acid (Cumic acid) is an aromatic monoterpenoid isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid shows antifungal activities. 4-Isopropylbenzoic acid is also a reversible and unco...
T3001 Honokiol NSC 293100 ERK , HCV Protease , MEK , Akt , Autophagy
Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.
T25327 Didemnin B NSC 325319,NSC325319,NSC-325319,Didemnin-B Antiviral
Didemnin B (Didemnin-B) is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum that has antiviral and antitumor activity.
T3003 5-hydroxytryptophan NSC-92523 Others , Endogenous Metabolite
5-hydroxytryptophan (NSC-92523) is the immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
T19676 Tributyrin NSC661583,NSC 661583,NSC-661583 Apoptosis
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracell...
T3362 Eupatilin NSC 122413 PPAR , Autophagy
Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.
TN2077 (+/-)-Pinocembrin NSC 43318,(±)-5,7-Dihydroxyflavanone GPR , Others
(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.
TMO2685 10-Hydroxydecanoic Acid NSC 15139 Antibacterial
10-Hydroxydecanoic Acid (NSC 15139) has antibacterial, anti - cancer and anti - radiation activity.
T1166 Ellipticine NSC 71795,Elliptisine Topoisomerase
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6...
TJS0405 Lucidin NSC 30546,Henine Others
1. Lucidin (NSC-30546) and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
T20257 Methyl anisate Methyl 4-anisate,NSC7324,NSC-7324,NSC 7324 Endogenous Metabolite
Methyl anisate (NSC 7324) is a human endogenous metabolite.
T0966 Sennoside A NSC 112929 MAO , HIV Protease
Sennoside A (NSC-112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
TN7059 Deoxylimonin NSC 314317,desoxylimonin Others
Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.
T7131 Antineoplaston A10 NSC-648539 Apoptosis , Endogenous Metabolite , Ras
Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.
T4S0931 Pseudolaric acid A NSC 615487 Others , Antifungal
Pseudolaric acid A (NSC 615487) and -B can inhibit the growth of particular cell type.
T6519 Gramine NSC 16892,Donaxine Adiponectin receptor , Reverse Transcriptase , Adrenergic Receptor
Gramine (Donaxine), a natural indole alkaloid, present in several plant species, acts as an active adiponectin receptor (AdipoR) agonist, with IC50s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively. Gramine is als...
T5982 3-Methoxybenzoic acid m-Methoxybenzoic acid,NSC 9264,NSC 27014,3-Anisic acid Endogenous Metabolite
3-Methoxybenzoic acid (NSC 27014) is a food additive,and has antibacterial activity.
T0968 Paclitaxel Taxol,NSC 125973 Apoptosis , Microtubule Associated , Autophagy
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
T0131 Cepharanthine NSC-623442 Apoptosis , TNF , HIV Protease , Autophagy
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.
T1571 Estriol NSC-12169,Oestriol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , MRP , Endogenous Metabolite
Estriol (Oestriol) is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. During PREGNANCY, a large amount of estriol is...
T5784 Topotecan NSC 609669,SKF 104864A Topoisomerase , Autophagy
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
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Natural Products

NSC 42196
T4987
Synonym: Calcium α-D-heptagluconate hydrate,Calcium glucoheptonate
Target: Others, Endogenous Metabolite
Ascaridole
T25114
Synonym: NSC-406266,NSC 406266,NSC406266
Target: Parasite
Valencene
T17214
Synonym: NSC 148969,NSC-148969,NSC148969
Target: Others, Antioxidant, NF-κB
Phenyl salicylate
T20250
Synonym: NSC-33406,NSC 33406,NSC33406
Target: Others
Iberin
T15544
Synonym: NSC 321801
Target: Endogenous Metabolite
3-Methylcarbazole
T64343
Synonym: NSC 10154
Target: Others
Lobelanidine
T32832
Synonym: NSC-95097,8,10-Diphenyllobelidiol,NSC 95097,NSC95097
Target: AChR
2'-Deoxyadenosine
T20041
Synonym: NSC-141848,NSC141848,NSC 141848
Target: Endogenous Metabolite
Rottlerin
T16791
Synonym: Mallotoxin,NSC 56346,NSC 94525
Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy
Physalin B
TN2063
Synonym: NSC-287088
Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD
Canthin-6-one
TN1466
Synonym: NSC 103003
Target: Antifungal
Ursolic acid
T0722
Synonym: Malol,Urson,NSC 167406,NSC-4060,Prunol
Target: Endogenous Metabolite, Autophagy
Thiobarbituric acid
T20550
Synonym: NSC4733,NSC 4733,NSC-4733
Target: Antibacterial
Stearamide
T20091
Synonym: Stearic acid amide,NSC 66462,NSC66462,NSC-66462
Target:
Valinomycin
TP1072
Synonym: NSC 122023
Target: Apoptosis, PTEN, Antibacterial, Antibiotic, Autophagy
Amphotericin B
T1067
Synonym: NSC 527017
Target: Antibiotic, Antifungal
3-Phenylpropanal
T20312
Synonym: NSC-9271,Phenylpropyl aldehyde,NSC9271,NSC 9271
Target: Others
Gentisein
T19931
Synonym: NSC 329491,NSC329491,NSC-329491
Target: Serotonin Transporter
Testosterone acetate
TC0025
Synonym: NSC523836,NSC-523836,NSC 523836
Target: Others
Daunomycinone
T20699
Synonym: Daunomycinon,Leukaemomycinone C,NSC 109351,NSC-109351,NSC109351
Target: Antibiotic
Xyloidone
T19962
Synonym: NSC-106453,NSC106453,Dehydro-α-lapachone,NSC 106453,Dehydrolapachone,NSC 629748
Target: Antifungal
Naringenin
T2838
Synonym: Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875
Target: P450, Influenza Virus, Reactive Oxygen Species, Endogenous Metabolite, PPAR
Maytansine
T21351
Synonym: NSC-153858,NSC153858,Maitansina,NSC 153858,Maitansine
Target: Microtubule Associated, Antibiotic
Jineol
T32291
Synonym: NSC694081,3,8-Quinolinediol,NSC 694081,NSC-694081
Target: Others
Geldanamycin
T6343
Synonym: NSC 122750
Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic
Robinin
T2S0265
Synonym: NSC 9222
Target: TLR
Dicentrine, (-)-
T20225
Synonym: L-Dicentrine,NSC 251699,NSC251699,NSC-251699
Target: Others
Thymoquinone
T4088
Synonym: NSC 2228,Thymoquinon
Target: BCL
α-Cyclodextrin
T17303
Synonym: Alfadex,NSC269470,NSC 269470,NSC-269470
Target: Others
4-Isopropylbenzoic acid
T20488
Synonym: NSC1907,NSC-1907,NSC 1907,Cumic acid
Target: Antifungal
Honokiol
T3001
Synonym: NSC 293100
Target: ERK, HCV Protease, MEK, Akt, Autophagy
Didemnin B
T25327
Synonym: NSC 325319,NSC325319,NSC-325319,Didemnin-B
Target: Antiviral
5-hydroxytryptophan
T3003
Synonym: NSC-92523
Target: Others, Endogenous Metabolite
Tributyrin
T19676
Synonym: NSC661583,NSC 661583,NSC-661583
Target: Apoptosis
Eupatilin
T3362
Synonym: NSC 122413
Target: PPAR, Autophagy
(+/-)-Pinocembrin
TN2077
Synonym: NSC 43318,(±)-5,7-Dihydroxyflavanone
Target: GPR, Others
10-Hydroxydecanoic Acid
TMO2685
Synonym: NSC 15139
Target: Antibacterial
Ellipticine
T1166
Synonym: NSC 71795,Elliptisine
Target: Topoisomerase
Lucidin
TJS0405
Synonym: NSC 30546,Henine
Target: Others
Methyl anisate
T20257
Synonym: Methyl 4-anisate,NSC7324,NSC-7324,NSC 7324
Target: Endogenous Metabolite
Sennoside A
T0966
Synonym: NSC 112929
Target: MAO, HIV Protease
Deoxylimonin
TN7059
Synonym: NSC 314317,desoxylimonin
Target: Others
Antineoplaston A10
T7131
Synonym: NSC-648539
Target: Apoptosis, Endogenous Metabolite, Ras
Pseudolaric acid A
T4S0931
Synonym: NSC 615487
Target: Others, Antifungal
Gramine
T6519
Synonym: NSC 16892,Donaxine
Target: Adiponectin receptor, Reverse Transcriptase, Adrenergic Receptor
3-Methoxybenzoic acid
T5982
Synonym: m-Methoxybenzoic acid,NSC 9264,NSC 27014,3-Anisic acid
Target: Endogenous Metabolite
Paclitaxel
T0968
Synonym: Taxol,NSC 125973
Target: Apoptosis, Microtubule Associated, Autophagy
Cepharanthine
T0131
Synonym: NSC-623442
Target: Apoptosis, TNF, HIV Protease, Autophagy
Estriol
T1571
Synonym: NSC-12169,Oestriol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite
Topotecan
T5784
Synonym: NSC 609669,SKF 104864A
Target: Topoisomerase, Autophagy
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Recombinant Proteins

Species：
Human (3)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (2)
Tag：
C-6xHis (1)
C-His (1)
N-10xHis-SUMO (1)
N-6xHis-SUMO (1)
Cat No. Product Name Species Expression System
TMPH-01799 Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) Human E. coli
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPK-01155 MANSC1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved ...
TMPH-01798 Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) Human E. coli
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream...
TMPJ-00549 MANSC1 Protein, Human, Recombinant (His) Human HEK293 Cells
MANSC domain-containing protein 1(MANSC1) is encoded by MANSC1 gene. MANSC1 is a Single-pass type I membrane protein which contains 1 MANSC domain. It is widely expressed in many tissues and mainly located in membrane.
Cat No. Product Name
L1380 Transcription Factor-Targeted Compound Library

695 compounds
Well-chosen 695 compounds with unique structures targeting transcription factor;

Libraries

Transcription Factor-Targeted Compound Library
L1380
Compounds: 695
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