Powder: -20°C for 3 years
In solvent: -80°C for 2 years
SU-4312, also known as DMBI, is a potent and selective inhibitor of <a href="/target/VEGFR" style="display: inline; color: #c13a36">VEGFR</a> and <a href="/target/PDGFR" style="display: inline; color: #c13a36">PDGFR</a> <a href="/target/Tyrosine_Kinases" style="display: inline; color: #c13a36">Tyrosine Kinases</a> (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal <a href="/target/NOS" style="display: inline; color: #c13a36">NOS</a>.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 47.00 | |
5 mg | In stock | $ 85.00 | |
10 mg | In stock | $ 144.00 | |
25 mg | In stock | $ 261.00 | |
50 mg | In stock | $ 403.00 | |
100 mg | Inquiry | $ 614.00 |
Description | SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. |
Targets&IC50 | VEGFR:0.8 μM, PDGFR:19.4 μM |
Synonyms | NSC 86429, SU 4312 |
Molecular Weight | 264.328 |
Formula | C17H16N2O |
CAS No. | 5812-07-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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SU4312 5812-07-7 Angiogenesis Tyrosine Kinase/Adaptors PDGFR VEGFR NSC 86429 Inhibitor inhibit Vascular endothelial growth factor receptor Platelet-derived growth factor receptor SU 4312 SU-4312 inhibitor