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Deoxylimonin

Name: Deoxylimonin
Brand: TargetMol
SKU: TN7059
Price: 100 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7059Cas No. 989-23-1

Alias NSC 314317, desoxylimonin

Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.

Deoxylimonin

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Purity: 99.43%

Catalog No. TN7059Alias NSC 314317, desoxylimoninCas No. 989-23-1

Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$100	In Stock	In Stock
5 mg	$247	In Stock	In Stock
10 mg	$396	In Stock	In Stock
25 mg	$648	In Stock	In Stock
50 mg	$912	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$288	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.43%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC

Product Introduction

Deoxylimonin AI Summary

Deoxylimonin exhibits anti-inflammatory activity, demonstrated by an 11.23% inhibition of ear swelling in a mouse model of xylene-induced ear swelling. Additionally, it shows analgesic activity by reducing writhing numbers by 22.57% in a mouse model of acetic-acid-induced writhing. Furthermore, Deoxylimonin displays antiproliferative activity against human cancer cells, with IC50 values of 5500.0 nM for MCF7 cells and 1700.0 nM for MDA-MB-435 cells, as measured by [3H]-thymidine incorporation assay after 48 hours of incubation..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Deoxylimonin (NSC 314317) is a triterpenoid isolated from grapefruit seeds.
Synonyms	NSC 314317, desoxylimonin

Chemical Properties

Molecular Weight	454.51
Formula	C₂₆H₃₀O₇
Cas No.	989-23-1
Smiles	[H][C@]12CC(=O)OC[C@@]11[C@@]([H])(CC(=O)[C@@]3(C)C4=CC(=O)O[C@@]([H])(c5ccoc5)[C@]4(C)CC[C@]13[H])C(C)(C)O2
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (121.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2002 mL	11.0009 mL	22.0017 mL	110.0086 mL
5 mM	0.4400 mL	2.2002 mL	4.4003 mL	22.0017 mL
10 mM	0.2200 mL	1.1001 mL	2.2002 mL	11.0009 mL
20 mM	0.1100 mL	0.5500 mL	1.1001 mL	5.5004 mL
50 mM	0.0440 mL	0.2200 mL	0.4400 mL	2.2002 mL
100 mM	0.0220 mL	0.1100 mL	0.2200 mL	1.1001 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc