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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3595 | Resmetirom | VIA-3196,MGL3196 | Thyroid hormone receptor(THR) |
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist. | |||
T14343 | Atreleuton | ABT-761,VIA-2291 | Others |
Atreleuton (ABT-761) is a potent and selective inhibitor of leukotriene formation[1][2][3]. As a reversible and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor, Atreleuton (ABT-761) exhibits selectivity. | |||
T22168 | Vialinin A | Terrestrin A | DUB |
Vialinin A (Terrestrin A), a p-terphenyl compound, exhibits antioxidant properties and acts as a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Its efficacy in autoimmune diseases an... | |||
T21662L | Cadherin Peptide, avian Acetate | Cadherin Peptide, avian Acetate (127650-08-2 Free base) | Others |
Cadherin Peptide, avian Acetate is a peptide with the sequence Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH2. Cadherins are a class of type-1 transmembrane proteins. | |||
T80446 | ω-Conotoxin FVIA | Calcium Channel | |
ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerve injury. This compound has potential utility in the research o... | |||
T80458 | ω-Conotoxin CVIA | Calcium Channel | |
ω-Conotoxin CVIA, a 27-amino acid neuropeptide, functions as a blocker of voltage-sensitive calcium channels (VSCCs) [1]. | |||
T80520 | ω-conotoxin MoVIA | Calcium Channel | |
ω-Conotoxin MVIIA is a potent, selective inhibitor of Ca_v2.2, exhibiting an IC_50 of 0.33 μM in the SH-SY5Y fluorimetric hCa_v2.2 assay [1]. | |||
T75727 | ω-Conotoxin GVIA TFA | ||
ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca 2+ channel [1] . | |||
T124019 | Isosalviamine A | ||
Isosalviamine A is a useful organic compound for research related to life sciences and the catalog number is T124019. | |||
T124509 | Vesuvianic acid | ||
Vesuvianic acid is a useful organic compound for research related to life sciences and the catalog number is T124509. | |||
T34500 | Salviarin | ||
Salviarin is a clerodane diterpene isolated from Salvia splendens. | |||
T124077 | Salvianan | ||
Salvianan is a useful organic compound for research related to life sciences and the catalog number is T124077. | |||
T19089 | (Z)-Viaminate | Ethyl 4-((2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido)benzoate | Others |
(Z)-Viaminate is a derivative of Retinoic acid. | |||
T75594 | Harpactira Baviana Venom | ||
Harpactira Baviana Venom (Baboon Tarantula Venom), derived from the king baboon spider, modulates Na V 1.8 and induces hyperalgesia [1] [2]. | |||
TP2062 | ω-Conotoxin GVIA | ||
Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo. | |||
T124018 | Isosalviamine B | ||
Isosalviamine B is a useful organic compound for research related to life sciences and the catalog number is T124018. | |||
T39980 | ErSO | Others | |
ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer. | |||
T9212 | IMB-301 | Others , HIV Protease | |
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model. | |||
T8400 | Pamidronic acid | Wnt/beta-catenin | |
Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells | |||
T0168 | Estradiol (cypionate) | Depofemin,Estradiol cypionate | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor. | |||
T4055 | Etoxazole | Others | |
Etoxazole is an acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection. | |||
T0313 | Evans blue | Direct Blue 53,C.I. 23860 | GluR |
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT). | |||
T6344 | Sevelamer hydrochloride | Sevelamer HCl | FXR , Autophagy |
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption. | |||
T37538 | Amifostine thiol | ||
Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3]. | |||
T27094 | CT-2584 | CT2584 | |
CT-2584 is an angiogenesis inhibitor and lysophosphatidic acid acyltransferase inhibitor. CT-2584 inhibits phospholipid signaling. By inhibiting CTP:choline-phosphate cytidylyltransferase (CT), CT-2584 caused de novo pho... | |||
TP2030 | Gastrin I, human | Gastrin I (human) | cholecystokinin |
Gastrin I, human (Gastrin I (human)) is an endogenous peptide produced in the stomach that increases pepsinogen and acid secretion via the CCK2 receptor in the rat. | |||
T6191 | Tasisulam | LY573636 | Apoptosis , Caspase |
Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway. | |||
TP2030L1 | Gastrin I (human) acetate | Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate | cholecystokinin |
Gastrin I (human) acetate (Gastrin-17 acetate) is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. | |||
T17192 | Ubiquitin Isopeptidase Inhibitor I, G5 | NSC144303 | Apoptosis |
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively). | |||
T3644 | U93631 | GABA Receptor | |
GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. Accelerates the decay of GABA-induced Cl- currents with little effect on peak amplitude... | |||
T4216 | STAT5-IN-1 | STAT5 Inhibitor | STAT |
STAT5-IN-1 (STAT5 Inhibitor) is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 domain. | |||
T18831 | Thalidomide-propargyl | Others , Ligand for E3 Ligase | |
Thalidomide-propargyl, a Thalidomide-derived Cereblon ligand, facilitates the recruitment of Cereblon. It can be attached to the protein ligand via a linker, producing IMiD-containing PROTACs. | |||
T3592 | MQAE | Others | |
MQAE, a fluorescent chloride ion indicator, is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells. MQAE is quenched via collision with chloride. | |||
T5367 | 3-TERT-BUTYL-4-HYDROXYANISOLE | Others | |
3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination. | |||
T9015 | LY900009 | Gamma-secretase | |
LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein. | |||
T24733 | Roxifiban acetate | MK 0853,DMP754,DMP 755,DMP 754 acetate,DMP 754,DMP-754 acetate,DMP754 acetate,DMP-754 | Integrin |
Roxifiban acetate(DMP 754 acetate) is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in the study of human thrombocytopenia. | |||
T3995 | Amcasertib | BBI503 | Stemness kinase |
Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases. | |||
T15069 | DBCO-PEG4-Biotin | ADIBO-NH-PEG2-Biotin | Others |
DBCO-PEG4-Biotin (ADIBO-NH-PEG2-Biotin) is an azadibenzocyclooctyne-biotin derivative containing a biotin moiety and 4 PEGs.DBCO-PEG4-Biotin is a versatile biotinylation reagent that introduces a portion of biotin into ... | |||
TP1345 | Kisspeptin-10, human (TFA)(374675-21-5,FREE) | GPR , Kisspeptin | |
Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i... | |||
T19675 | SM360320 | CL-087,SM 360320,CL 087,1V136,SM-360320,CL087 | TLR |
SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for ... | |||
T8694 | ML406 | Antibacterial , Antibiotic | |
ML406 shows anti-tubercular activity via MtbbioA (DAPA synthase) enzyme inhibition(IC50 : 30 nM) | |||
T28077 | MMPP | VEGFR , STAT | |
MMPP is a novel VEGFR2 inhibitor with anti-inflammatory and potential anticancer activity, inhibits STAT3, inhibits angiogenesis via VEGFR2/AKT/ERK/NF-kappaB pathway, and can be used to alleviate myocardial injury. | |||
T20689 | Temocaprilat | RNH-5139,RS-5139,RNH 5139,RNH5139,RS5139,RS 5139 | Angiotensin-converting Enzyme (ACE) |
Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and that many of other ACE inhibitors have low affinity for cMOA... | |||
TQ0121 | VH-298 | Others , HIF , Ligand for E3 Ligase | |
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by P... | |||
T18018 | HS-27 | Others , HSP | |
HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC. HS-27 can be used in see-and-treat paradigms. | |||
T3155 | SMER28 | Autophagy | |
SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells via an mTOR-independent mechanism and prevented the accumulation of amyloid beta peptide. | |||
T50093 | MASM7 | Others | |
MASM7 also known as MASM7, is a compound used as a molecular structural unit. It is a mitochondrial fusion protein activator that enables mitochondrial fusion via mitochondrial fusion proteins. | |||
T70277 | Cynandione A | Others | |
Cynandione A, an acetophenone derived from Cynanchum wilfordii, has anti-inflammatory activity and significantly reduces pro-inflammatory cytokine overexpression via macrophage α7 nAChR activation and subsequent IL-10 ex... | |||
T34262 | RAPTA-C | Apoptosis | |
RAPTA-C induces EAC cell cycle arrest and apoptosis via the mitochondrial and p53-JNK pathways, and can be used in the study of breast and ovarian cancer. | |||
T4377 | Pimodivir | VX-787 | Influenza Virus |
Pimodivir (VX-787), an influenza A virus polymerases inhibitor via oral, interacts with the viral PB2 subunit. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2173 | Salvianolic acid D | (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid | Others |
Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) and notoginseng triterpenes can promote EA-hy926 and expression of protein with protective effec... | |||
T3149 | Salvianolic Acid C | Others , P450 | |
Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia. | |||
T3208 | Brevianamide F | Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp) | BCRP , PI3K , Antibacterial |
Brevianamide F (Cyclo(L-Pro-L-Trp)), also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. Brevianamide F possess interesting breast cancer resistance protein inhibitory acti... | |||
T4589 | 9'''-Methyl salvianolate B | 9'''-MethyllithosperMate B | Others |
9'-Methyllithospermate B is a natural extract obtained from Cynoglossum columnae. | |||
TN2174 | Salvianolic acid E | Others | |
Salvianolic acid E is a water-soluble constituent isolated from Salvia miltiorrhiza. | |||
TN6789 | Neosalvianen | Others | |
Neosalvianen was isolated from Salvia miltiorrhiza. | |||
T4961 | 9''-Methyl salvianolate B | 9'-Methyl lithospermate B | Others |
9'-Methyl lithospermate B is a phenolic compound extracted from Radix Salvia miltiorrhizae. | |||
T2727 | Salvianolic acid B | Others | |
Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia extract. It plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect | |||
TN2175 | Salvianolic acid F | Caspase | |
The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6. | |||
TN1127 | Salviaflaside | Antioxidant | |
Salviaflaside is the main bioactive component of Prunella vulgaris and has antioxidant activity. | |||
T5725 | Salvianolic acid B | lithospermic acid B,Dan Shen Suan B | Sirtuin , Autophagy |
Salvianolic acid B is a water-soluble antioxidant from Salvia extract. Salvianolic acid B plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect. | |||
T6S0444 | Salvianolic acid A | Dan Phenolic Acid A | MMP |
Salvianolic acid A (Dan Phenolic Acid A) could protect the blood brain barrier through inhibition of matrix metallopeptidase 9 (MMP-9) and anti-inflammation. | |||
T82818 | Brevianamide R | ||
Brevianamide R (compound 4), an alkaloid, was isolated from the fungus Aspergillus versicolor cultured on fermented rice [1]. | |||
T39825 | (Rac)-Salvianic acid A | (Rac)-Danshensu | |
(Rac)-Salvianic acid A, also known as (Rac)-Danshensu, is a phenolic acid compound that possesses exceptional radical scavenging and antioxidant properties. | |||
TN6498 | Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester) | ||
Stevia impurity (13-[(2-O-6-deoxy-β-D-glucopyranosyl-3-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-D-glucopyranosyl ester) is a natural product for research related to life sciences. The ... | |||
T79986 | Brevianamide M | ||
Brevianamide M (compound 4), a metabolite of the endophytic fungus Aspergillus versicolor isolated from the marine brown alga Sargassum, exhibits antimicrobial activity against Escherichia coli and Staphylococcus aureus ... | |||
TN1801 | Isosalvianolic acid C | LDL | |
Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F . | |||
T75553 | Salvianan A | ||
1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1]. | |||
T75617 | Salviandulin E | ||
Salviandulin E, a diterpenoid isolated from Salvia leucantha CAV., exhibits antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites, demonstrating an IC50 value of 0.72 µg/mL [1] [2]. | |||
T82819 | Brevianamide Q | ||
Brevianamide Q (Compound 3), an alkaloid isolated from the fungus Aspergillus versicolor [1], exhibits distinct structural characteristics. | |||
TN2451 | Isosalvianolic acid B | NF-κB | |
Isosalvianolic acid B is a natural from Salviae miltiorrhizae | |||
TN4935 | Salvianolic acid Y | Others | |
Salvianolic acid Y, isolated from Salvia officinalis, is a protector of PC12 cells against hydrogen peroxide-induced injury from Salvia officinalis. | |||
TN4812 | Pluviatolide | AChR | |
(-)-Pluviatolide can inhibit electrically-induced and acetylcholine-induced contraction in the isolated guinea-pig ileum. | |||
TN5678 | Salviaplebeiaside | ||
Salviaplebeiaside is a natural product from Vitex negundo var. cannabifolia. | |||
T83278 | 6,7-Dihydrosalviandulin E | ||
6,7-Dihydrosalviandulin E, a neo-clerodane diterpenoid, can be isolated from the aerial parts of Salvia leucantha, also known as Salvileucalin A. [1] | |||
T30784 | Cedrene | AI3-51328,AI3 51328,AI351328 | |
Cedrene can regulate hepatic steatosis via the cAMP-PKA pathway. | |||
T3890 | Verbenalin | Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin | Others |
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis. | |||
T3797 | Isosilybin | Isosilybinin,Isosilibinin,Silymarin,Silybin B,Q-100795 | P450 |
Isosilybin (Isosilibinin) and Silybin might be suitable candidates to design potent PXR antagonists to prevent drug-drug interactions via CYP3A4 in cancer patients. | |||
T2911 | Stevioside | TLR | |
A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference. | |||
T9294 | DL-Valine | Valine, DL-,H-DL-Val-OH,2-Amino-3-methylbutanoic acid | Others |
DL-Valine (H-DL-Val-OH) is 2-amino-3-methylbutanoic acid.It is synthesized in plants via several steps starting from pyruvic acid. | |||
T4738 | Sodium 2-hydroxybutanoate | 2-Hydroxybutyric acid sodium salt,DL-2-Hydroxybutyric Acid Sodium Salt,alpha-hydroxybutyrate,SODIUM 2-HYDROXYBUTYRATE | Others , Endogenous Metabolite |
Sodium 2-hydroxybutanoate (alpha-hydroxybutyrate) is formed as a by-product of the formation of alpha-ketobutyrate via a reaction catalyzed by lactate dehydrogenase (LDH) or alpha-hydroxybutyrate dehydrogenase (alphaHBDH... | |||
T4853 | TRIA-662 | 3-Carbamoyl-1-methylpyridinium Chloride,1-Methylnicotinamide chloride,1-methylpyridin-1-ium-3-carboxamide hydrochloride,Nicotinamide Chloromethylate | Others , Endogenous Metabolite |
TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system. | |||
TN1369 | Alloimperatorin | Prangenidin | Others |
Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficient... | |||
T40646 | Lipoteichoic acid | Complement System | |
Lipoteichoic acid, a polymer of Staphylococcus aureus cell wall, activates the complement system by inducing C3 and inhibiting CD55, and reduces fat deposition via the IGF-1 pathway. | |||
T3895 | Polyphyllin I | Apoptosis , Akt , JNK , PDK , mTOR , Autophagy | |
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha... | |||
T5S1261 | Methylophiopogonanone B | Ras | |
1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation. | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T4820 | Maleimide | 2,5-Pyrroledione | Others |
Maleimide (2,5-Pyrroledione) (2,5-Pyrroledone) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its b... | |||
T13818 | Phytohemagglutinin | PHA-M | Apoptosis |
Phytohemagglutinin (PHA-M) is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3. Anti-tumor activity | |||
TN4661 | Nodosin | IL Receptor , Autophagy | |
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp... | |||
TMS2171 | (±)-Naringenin | Salipurpol,Naringenine,Naringenin | Potassium Channel |
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes. | |||
T4733 | Sucrose | D(+)-Sucrose,D-(+)-Saccharose | Others , Endogenous Metabolite |
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. | |||
TN4114 | Gardenin A | ERK , LDL , MAPK , PKA , PKC | |
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects. | |||
T6S1367 | Procyanidin B2 | Proanthocyanidin B2 | Reactive Oxygen Species , NOD |
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ... | |||
T3397 | Epmedin C | Baohuoside-VI,Epimedin C | Others |
Epmedin C (Baohuoside-VI) was metabolized via desugarization, dehydrogenation, hydrogenation, dehydroxylation, hydroxylation, demethylation and glucuronidation pathways in vivo. It has potential activity against osteopor... | |||
T3345 | Hederasaponin B | Eleutheroside M,Hederacoside B | Others , Virus Protease |
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis. | |||
T2596 | N-Acetyl-β-Asp-Glu | Others | |
N-Acetyl-β-Asp-Glu is a peptide neurotransmitter, the third most common neurotransmitter in the mammalian nervous system. NAAG consists of N-acetylaspartate (NAA) and glutamate coupled via a peptide bond. | |||
T5276 | 4,4'-Disulfanediylbis(2-aminobutanoic acid) | DL-Homocystine | Others , Endogenous Metabolite |
4,4'-Disulfanediylbis(2-aminobutanoic acid) (DL-Homocystine) is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzym... | |||
T8166 | Pennogenin 3-O-beta-chacotrioside | Autophagy | |
Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla with anti-colorectal cancer activity. It modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Be... | |||
T3863 | Chikusetsusaponin IVa | Calenduloside F | AMPK |
Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01843 | SEMA6A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SE... | |||
TMPJ-01392 | IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His) | Cavia porcellus | E. coli |
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and per... | |||
TMPY-05141 | BETVIA Protein, Betula pendula, Recombinant | Betula pendula | E. coli |
BETVIA Protein, Betula pendula, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is P15494.2. | |||
TMPJ-00640 | CTLA-4 Protein, Cavia porcellus, Recombinant (His) | Cavia porcellus | P. pastoris (Yeast) |
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 KDa and the accession number is H0VUB1. | |||
TMPY-05888 | Influenza A H1N1 (A/Pavia/65/2016) Hemagglutinin/HA Protein (His) | H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Pavia/65/2016) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59 kDa and the accession number is A0A1L6YSP8. | |||
TMPJ-00261 | TGF beta 2 Protein, Mouse/Rat, Recombinant | Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci... | |||
TMPK-00810 | TPA Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin... | |||
TMPH-02151 | OXCT1 Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of... | |||
TMPJ-01468 | Pro-Beta NGF Protein, Human, Recombinant | Human | E. coli |
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite... | |||
TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPH-00010 | MMP-14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tiss... | |||
TMPK-00735 | CXCL13/BCA-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve li... | |||
TMPY-03958 | TGF alpha Protein, Human, Recombinant | Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared... | |||
TMPK-00474 | IL-22RA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component o... | |||
TMPJ-00166 | SCF Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto... | |||
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPY-00395 | Insulin Protein, Human, Recombinant | Human | P. pastoris (Yeast) |
INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul... | |||
TMPY-02157 | GST Protein, Schistosoma japonicum, Recombinant | Schistosoma japonicum | Baculovirus Insect Cells |
Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated int... | |||
TMPY-02904 | TLR4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans... | |||
TMPY-05004 | FGF-4 Protein, Human, Recombinant | Human | E. coli |
FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati... | |||
TMPY-02115 | R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) | Human | HEK293 Cells |
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in devel... | |||
TMPJ-00865 | VEGF121 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD... | |||
TMPJ-00994 | LTBR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce... | |||
TMPY-05176 | AMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ... | |||
TMPY-01648 | TREML2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like... | |||
TMPY-01085 | VLDLR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-02245 | SNAP-25 Protein, Human, Recombinant (His) | Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains... | |||
TMPH-01514 | IGIP Protein, Human, Recombinant (His & TF) | Human | Baculovirus Insect Cells |
Enhances IgA secretion from B-cells stimulated via CD40. | |||
TMPH-03587 | GspB Protein, S. gordonii, Recombinant (GST) | Streptococcus gordonii | E. coli |
Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-a... | |||
TMPK-00958 | BTN1A1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition. | |||
TMPH-01621 | BRCC3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes... | |||
TMPH-02373 | Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) | Klebsiella pneumoniae | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol... | |||
TMPH-01513 | IGIP Protein, Human, Recombinant (His & KSI) | Human | E. coli |
Enhances IgA secretion from B-cells stimulated via CD40. | |||
TMPH-03046 | TBP1 Protein, MenB, Recombinant (His & Myc) | MenB | E. coli |
Neisseria acquires iron by extracting it from serum transferrin (TF) in its human host. Acts as a TF receptor and is required for TF utilization. Binds both apo- and holo-TF, via the TF C-terminus. | |||
TMPH-00156 | Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His) | Bacillus amyloliquefaciens | E. coli |
Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates. Ribonuclease Protein, Bacillus amyloliquefaciens, Recombinant (His)... | |||
TMPH-03265 | CMKLR2 Protein, Rat, Recombinant (His) | Rat | E. coli |
Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates... | |||
TMPJ-00358 | DR6 Protein, Mouse, Recombinant (hFc & His) | Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may ... | |||
TMPH-03011 | EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) | Mycobacterium tuberculosis | E. coli |
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth fact... | |||
TMPH-01693 | MAP3K14 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Promotes proteolytic processing of NFKB2/P100, which leads to activation of NF-ka... | |||
TMPH-03613 | NblA Protein, Synechococcus elongatus, Recombinant (His & Myc) | Synechococcus elongatus | E. coli |
Involved in phycobilisome (PBS) degradation during nutrient deprivation. May mark the PBS for degradation by covalent association with PBS components or may disrupt the PBS via ionic interactions. NblA Protein, Synechoco... | |||
TMPH-01100 | CLINT1 Protein, Human, Recombinant (His) | Human | E. coli |
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. CLI... | |||
TMPH-03488 | Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) | Serratia marcescens | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant ... | |||
TMPJ-00352 | CD98 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
CD98 is a multifunctional glycoprotein that is involved in various biological processes such as amino acid transport, cell adhesion, diffusion, adhesion, and proliferation. CD98 can interact with CD147 to induce integrin... | |||
TMPJ-01050 | GRB2 Protein, Human, Recombinant (His) | Human | E. coli |
As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated E... | |||
TMPH-00521 | G3P Protein, Enterobacteria phage M13, Recombinant (His) | Enterobacteria phage M13 | P. pastoris (Yeast) |
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process. During the initial step of infection, G3P mediates adsorption of the phage to i... | |||
TMPH-01602 | LAMA5 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix co... | |||
TMPH-02675 | GCGR Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and g... | |||
TMPK-00109 | Artemin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored... | |||
TMPH-03739 | Alginate lyase Protein, Azotobacter vinelandii, Recombinant (His & Myc & SUMO) | Azotobacter vinelandii | E. coli |
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. Splits ManA-ManA and ManA-GulA bonds, but not GulA-ManA or GulA-Gu... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L8600 | Ubiquitination Compound Library | 210 compounds | |
A unique collection of 210 ubiquitination related small chemicals can be used for high throughput and high content screening; | |||
L3510 | Methylation Compound Library | 128 compounds | |
128 methylation-related compounds that can be used for high-throughput and high-content screening. | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L3700 | JAK-STAT Compound Library | 252 compounds | |
A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening; | |||
L6140 | Saccharide and Glycoside Natural Product Library | 362 compounds | |
A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L5510 | Drug-induced Liver Injury (DILI) Compound Library | 1001 compounds | |
A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening; | |||
L5300 | Mitochondria-Targeted Compound Library | 812 compounds | |
A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L6720 | Anti-COVID-19 Traditional Chinese Medicine Compound Library | 1147 compounds | |
A unique collection of 1147 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening; | |||
L9300 | Macrocyclic Compound Library | 210 compounds | |
210 macrocyclic compounds of known activity for high-throughput, high-content screening; |