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Ubiquitin Isopeptidase Inhibitor I, G5

Catalog No. T17192 CAS 108477-18-5

Synonyms: NSC144303

Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).

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Ubiquitin Isopeptidase Inhibitor I, G5 Chemical Structure

Ubiquitin Isopeptidase Inhibitor I, G5, CAS 108477-18-5

Pack Size	Availability	Price/USD
5 mg	In stock	$ 74.00
10 mg	In stock	$ 128.00
25 mg	In stock	$ 217.00
50 mg	In stock	$ 319.00
100 mg	In stock	$ 478.00
500 mg	5 days	$ 1,090.00

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Biological Description

Chemical Properties

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Description	Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
Targets&IC50	E1A/C9DN cells:1.6 μM, E1A cells:1.76 μM
In vitro	Ubiquitin Isopeptidase Inhibitor I, G5 is a more effective apoptosis inducer, with IC50 values of 1.76 μmol/L and 1.6 μmol/L in E1A and E1A/C9DN cells, respectively[1].

Synonyms	NSC144303
Molecular Weight	414.39
Formula	C19H14N2O7S
CAS No.	108477-18-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 20 mg/mL (48.26 mM), Sonication is recommended.

References and Literature

1. Aleo E, et al. Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis. Cancer Res. 2006 Sep 15;66(18):9235-44.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ubiquitin Isopeptidase Inhibitor I, G5 108477-18-5 Apoptosis NSC 144303 NSC-144303 NSC144303 Ubiquitin Isopeptidase Inhibitor I, G-5 inhibitor inhibit

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