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TargetMol | Compound Library

MAPK Inhibitor Library

Catalog No. L1400

Mitogen-activated protein kinases (MAPKs) are a highly conserved family of serine/threonine protein kinases involved in a variety of fundamental cellular processes such as proliferation, differentiation, motility, stress response, apoptosis, and survival. A broad range of extracellular stimuli including mitogens, cytokines, growth factors, and environmental stressors stimulate the activation of one or more MAPKK kinases (MAPKKKs) via receptor-dependent and -independent mechanisms. MAPKKKs then phosphorylate and activate a downstream MAPK kinase (MAPKK), which in turn phosphorylates and activates MAPKs. The MAPK Inhibitor Library by TargetMol, containing 500 compounds targeting MAPK signaling, can be used for research in MAPK signaling, and drug screening for related diseases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1400

MAPK Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 500 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Targets include ERK, JNK, MEK, p38, MAPK, Raf, RSK, MNK, etc;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

p38 MAPK
ERK
Apoptosis
Raf
Autophagy
MAPK
JNK
Ras
MEK
NF-κB
S6 Kinase
Akt
CDK
VEGFR
Src
TNF
Kras
Rho
MNK
c-Kit
mTOR
PDGFR
PI3K
Aurora Kinase
Casein Kinase
Caspase
Endogenous Metabolite
FLT
GSK-3
MLK
PKA
Bcl-2 Family
Antibacterial
Ferroptosis
Parasite
PKC
STAT
COX
c-RET
IGF-1R
IL Receptor
MMP
ROCK
TGF-beta/Smad
Antifungal
ASK
Bcr-Abl
EGFR
FGFR
JAK
AMPK
Antiviral
Cytochromes P450
DNA/RNA Synthesis
FAK
PARP
Reactive Oxygen Species
SGK
TOPK
ALK
Antibiotic
c-Fms
Cholinesterase (ChE)
Influenza Virus
KLF
NO Synthase
Serine Protease
Syk
TLR
Trk receptor
Tyrosine Kinases
AChR
ACK1
Antifection
Antioxidant
Aryl Hydrocarbon Receptor
Calcium Channel
Chk
Dehydrogenase
Drug Metabolite
Epigenetic Reader Domain
GPCR
GTPase
HCV Protease
Histone Methyltransferase
IRAK
Mitochondrial Metabolism
Mitophagy
Nrf2
PDK
P-gp
Pim
Potassium Channel
PPAR
PROTACs
PYK2
ROS
Transferase
Virus Protease
5-HT Receptor
Adrenergic Receptor
AhR
Apelin receptor
Aromatase
ATPase
BACE
Beta Amyloid
Beta-Secretase
BMI-1
BTK
cAMP
c-Met/HGFR
c-Myc
CSF-1R
DAPK
DNA Alkylation
DYRK
Ephrin Receptor
Estrogen/progestogen Receptor
Glucosidase
GluR
Glutathione Peroxidase
GPX
HBV
HER
HIF/HIF Prolyl-Hydroxylase
Hippo pathway
Histamine Receptor
HSP
Hydroxylase
iGluR
Interleukin
IκB/IKK
Kinesin
LDL
LRRK2
MELK
MyD88
NADPH-oxidase
NMDAR
p53
PAI-1
PD-1/PD-L1
PDE
PGE Synthase
Prostaglandin Receptor
Protease-activated Receptor
PTEN
RIP kinase
RXFP receptor
Sodium Channel
Tie-2
Topoisomerase
transporter
TRP/TRPV Channel
Tyrosinase
Wnt/beta-catenin