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Cat No. | Product Name | Synonyms | Targets |
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T26828 | BIT225 | BIT 225,BIT-225 | |
BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows ... | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T22831 | Protein kinase inhibitor H-7 dihydrochloride | H-7 dihydrochloride | PKC |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-... | |||
T22195 | CBFβ Inhibitor | 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine | DNA/RNA Synthesis |
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1. | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T1383 | Bitoscanate | p-Phenylene diisothiocyanate,Biscomate,PDITC,1,4-Diisothiocyanatobenzene | Parasite |
Bitoscanate (PDITC) is used in the treatment of hookworms. | |||
T3593 | Src Inhibitor 1 | Src Kinase Inhibitor 1,Src-l1 | Src |
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor. | |||
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. | |||
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T6409 | ALK kinase inhibitor-1 | SAR348830 | Others |
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase. | |||
T10629 | Btk inhibitor 2 | BGB-3111 analog | BTK |
Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor. | |||
T15654 | Ketohexokinase inhibitor 1 | PF-06835919 | Others |
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively). | |||
TP2310 | Autocamtide-2-related inhibitory peptide | CaMK , Autophagy | |
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | |||
T83627 | Pim-1 kinase inhibitor 8 | Pim , PKC | |
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ... | |||
T22081 | FBPase-1 inhibitor-1 | Fructose 1,6-bisphosphatase-1 Inhibitor | Others |
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor. | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
T5831 | Selective PI3Kδ Inhibitor 1 | PI3K | |
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM). | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T67830 | P38α inhibitor 3 | p38 MAPK | |
p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation. | |||
T8864 | Thymidylate Kinase Inhibitor, YMU1 | Others | |
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site. | |||
T9706 | BTK inhibitor 17 | BTK | |
BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies. | |||
T9044 | SORT-PGRN interaction inhibitor 1 | Neurotensin Receptor | |
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM). | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T9725 | GSK-3β inhibitor 10 | Others | |
GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities. | |||
T6556 | K-Ras(G12C) inhibitor 9 | Raf | |
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T67899 | Topoisomerase II inhibitor 13 | Topoisomerase | |
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity. | |||
T9957 | LASV inhibitor 3.3 | Virus Protease | |
LASV inhibitor 3.3 is an inhibitor of Lassa fever virus (LASV) targeting lysosome-associated membrane protein 1 (LAMP1), a host factor that binds to the LASV glycoprotein (GP) during infection. | |||
T2159 | CaMKP Inhibitor | CaMK | |
CaMKP Inhibitor can inhibit CaMKP. | |||
T9178 | (E/Z)-GSK-3β inhibitor 1 | GSK-3β inhibitor 1 | GSK-3 |
(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy. | |||
T7677 | JNK Inhibitor VIII | TCS JNK 6o | JNK |
JNK Inhibitor VIII (TCS JNK 6o) is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively). | |||
T6788 | Bitopertin | Paliflutine,RO4917838,RG1678 | GlyT |
Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells. | |||
T21512 | MMP-2/MMP-9 Inhibitor I | MMP | |
MMP-2/MMP-9-IN-1 is a potent, highly selective and orally bioavailable inhibitor of type IV collagenases (MMP-9 and MMP-2) with an IC50 of 0.24 and 0.3 1 μM for MMP-9 and MMP-2, respectively. activity, which can be used ... | |||
T10866 | Cot inhibitor-2 | TNF , MAPK | |
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM. | |||
T78578 | GSK-3 Inhibitor XIII | GSK-3 | |
GSK-3 Inhibitor XIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity. | |||
T10687 | Casein Kinase II Inhibitor IV | Casein Kinase | |
Casein Kinase II Inhibitor IV is an inducer of epidermal keratinocyte differentiation. | |||
T35529 | HSMG-1 inhibitor 11e | Others | |
hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment. | |||
T17192 | Ubiquitin Isopeptidase Inhibitor I, G5 | NSC144303 | Apoptosis |
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively). | |||
T10853 | CNT2 inhibitor-1 | Others | |
CNT2 inhibitor-1 is a potent inhibitor of concentrative nucleoside transporter 2 (CNT2; IC50: 640 nM for hCNT2). | |||
T10599 | BRAF inhibitor | Raf | |
BRAF inhibitor is an inhibitor of B-Raf. | |||
T10985 | DDR Inhibitor | Discoidin Domain Receptor (DDR) | |
DDR inhibitor is a potent discidin domain receptor (DDR) inhibitor. The IC50 of DDR2 is 3.3 nM, and DDR1 has 53% inhibition at 1.5 nM. | |||
T2318 | Sacubitril/Valsartan | Sacubitril mixture with Valsartan,Valsartan,Sacubitril,LCZ696 | Apoptosis , RAAS , Neprilysin |
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure. | |||
T3725 | K-Ras(G12C) Inhibitor 6 | Raf | |
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. | |||
T11878 | LRRK2 inhibitor 1 | LRRK2 , CDK | |
LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM. | |||
T22135 | PPIase-Parvulin Inhibitor | Others | |
PPIase-Parvulin Inhibitor is a cell-pemeable inhibitor of the Pin1 and Pin4. | |||
T118066 | CDK9 inhibitor HH1 | 8019-9719 | CDK |
CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM. | |||
T9068 | Cucurbit[7]uril | Others | |
Cucurbit[7]uril is an emerging candidate for pharmaceutical excipients.Cucurbit[7]uril enhances photosensitization of porphyrins in Neuroblastoma cells | |||
T3042 | JAK2 Inhibitor V | JAK2 Inhibitor V Z3,Z3 | JAK |
JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner. | |||
T11950 | MAT2A inhibitor 2 | Others , Methionine Adenosyltransferase (MAT) | |
MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1467 | Cucurbitacin E | CDK , Autophagy | |
Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cucurbitacin E has prevention of neurodegeneration, it has pot... | |||
T20550 | Thiobarbituric acid | NSC4733,NSC 4733,NSC-4733 | Antibacterial |
Thiobarbituric acid (NSC-4733) has Antibacterial Activity. | |||
TN1013 | Cucurbitacin D | IL Receptor , JNK , STAT | |
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. | |||
T3S1471 | Cucurbitacin IIA | Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA | Apoptosis , Survivin |
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ... | |||
T6805 | Choline bitartrate | 2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium | Others , AChR |
Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcho... | |||
T5268 | D-Arabitol | D-Lyxitol | Others , Endogenous Metabolite |
D-Arabitol (D-Lyxitol) is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-product in humans. | |||
T5853 | Rubitecan | RFS 2000,9-Nitrocamptothecin | Topoisomerase |
Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a se... | |||
T21066 | Norepinephrine bitartrate salt | Adrenergic Receptor | |
Norepinephrine bitartrate salt is an adrenergic neurotransmitter. | |||
T4S1469 | Cucurbitacin IIb | Apoptosis , Others | |
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i... | |||
T3404 | Cucurbitacin B | Cuc B,DATISCACIN,Amarine | Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy |
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh... | |||
TQ0196 | Cucurbitacin I | NSC-521777,JSI-124,Elatericin B | JAK , STAT |
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity. | |||
T1064 | Norepinephrine bitartrate monohydrate | Levophed,Noradrenaline bitartrate monohydrate | Endogenous Metabolite , Adrenergic Receptor , Autophagy |
Norepinephrine bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator. | |||
TN1579 | Dihydrocucurbitacin B | 23,24-dihydrocucurbitacin B | IL Receptor , TNF , COX |
Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity. | |||
TQ0195 | 1,5-Anhydrosorbitol | Others , Endogenous Metabolite | |
1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food. | |||
TN2341 | Cucurbitacin Q1 | Others | |
Cucurbitacin Q1, a compound isolated from the fruit of Cucumis prophetarum, has been shown to be the pure trans component of cucurbitacin Q. | |||
T0332 | D-Sorbitol | Glucitol,Sorbitol,D-Glucitol | Others , Endogenous Metabolite |
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use... | |||
TN6313 | (19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol | ||
(19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol is a natural product for research related to life sciences. The catalog number is TN6313 and the CAS number is 332950-28-4. | |||
TN2574 | 10-O-Ethylcannabitriol | Others | |
10-O-Ethylcannabitriol is a natural product from Cannabis sativa L. | |||
TN3074 | 5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol | Others | |
5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN3074 and the CAS number is 81910-39-6. | |||
TN6274 | 3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al | ||
3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences. The catalog number is TN6274 and the CAS number is 85372-69-6. | |||
TN6956 | Cucurbitacin C | ||
Cucurbitacin C is a natural product. | |||
TN5949 | 5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol | ||
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN5949 and the CAS number is 85372-70-9. | |||
TN1533 | Cucurbitacin A | ROCK | |
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase. | |||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid | Phosphatase | |
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | |||
TN5993 | 16-Desoxycucurbitacin V | 3β,20S,25-Trihydroxycucurbita-5,23-dien-11-one | |
16-Desoxycucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5993 and the CAS number is 2081098-85-1. | |||
TN6333 | (19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6333 and the CAS number is 2281872-79-3. | |||
TN5974 | Cucurbitacin A 2-O-β-D-glucopyranoside | ||
Cucurbitacin A 2-O-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5974 and the CAS number is 1135141-76-2. | |||
TN6275 | 3,7,25-Trihydroxycucurbita-5,23-dien-19-al | 3β,7β,25-Trihydroxycucurbita-5,23-dien-19-al | |
3,7,25-Trihydroxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences. The catalog number is TN6275 and the CAS number is 85372-65-2. | |||
TN3073 | 5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol | Others | |
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN3073 and the CAS number is 85372-72-1. | |||
TN6345 | (19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol | ||
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6345 and the CAS number is 874287-87-3. | |||
TN1534 | Cucurbitacin B 2-O-beta-D-glucoside | Others | |
Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity. | |||
T83570 | (23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol | ||
(23E)-5β,19-epoxycucurbita-6,23,25(26)-triene-3β-ol, a cucurbitane triterpenoid, can be isolated from the seeds of Momordica charantia L. [1]. | |||
T4S1472 | Cucurbitacin S | ||
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities. | |||
TN5978 | 7β-Hydroxycucurbitacin B | ||
7β-Hydroxycucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5978 and the CAS number is 1135141-79-5. | |||
TN5995 | Cucurbitacin IIa 2-O-glucoside | Hemslecin A 2-O-glucoside | |
Cucurbitacin IIa 2-O-glucoside is a natural product for research related to life sciences. The catalog number is TN5995 and the CAS number is 77704-34-8. | |||
T81194 | Schibitubin I | ||
Schibitubin I, a lignin with neuroprotective activity, can be isolated from the fruits of Schisandra bicolor var. tuberculata [1]. | |||
TN6320 | (19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6320 and the CAS number is 1616120-83-2. | |||
TN6305 | 3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside | ||
3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside is a natural product for research related to life sciences. The catalog number is TN6305 and the CAS number is 81910-37-4. | |||
T82037 | Isocucurbitacin D | ||
Isocucurbitacin D is a compound recognized for its antitumor properties [1]. | |||
TN5990 | Cucurbitacin V | ||
Cucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5990 and the CAS number is 152340-37-9. | |||
TN6332 | (19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6332 and the CAS number is 1474062-47-9. | |||
T83578 | (19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol | ||
(19R,23E)-5b,19-Epoxy-19-ethoxycucurbita-6,23-diene-3b,25-diol, a cucurbitane-type triterpenoid, exhibited no activity against five cancer cell lines—MCF-7, HepG2, Du145, Colon205, and HL-60—when evaluated using the MTT ... | |||
T81690 | Neocucurbitacin A | STAT | |
Neocucurbitacin A (compound 7), a STAT3 inhibitor extracted from the pericarp of Aquilaria crassna, serves as a potential agent for anticancer research [1]. | |||
T6640 | Ribitol | Adonite,Adonitol | Others , Endogenous Metabolite |
Ribitol (Adonite) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis. | |||
TN1776 | Isocucurbitacin B | Others | |
Isocucurbitacin B has significant activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM. | |||
T82207 | Hexanorcucurbitacin D | ||
Hexanorcucurbitacin D, a cucurbitacin, is extractable from the roots of Trichosanthes cucumeroides and is utilized in cardiovascular disease (CVD) research [1]. | |||
TN3725 | Cucurbitadienol | ||
Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis... | |||
TN5988 | 16,25-Di-O-acetylcucurbitacin F | 16,25-O-Diacetyl-cucurbitane F,Cucurbitacin F 16,25-diacetate | |
16,25-Di-O-acetylcucurbitacin F is a natural product for research related to life sciences. The catalog number is TN5988 and the CAS number is 2062685-10-1. | |||
T83399 | 23,24-Dihydroisocucurbitacin D | ||
23,24-Dihydroisocucurbitacin D (compound 22) is a member of the cucurbitacins [1]. | |||
TN2909 | 3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al | Others | |
3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al is a natural product for research related to life sciences. The catalog number is TN2909 and the CAS number is 1446447-97-7. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02632 | SIRP alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is BAA20376.1. | |||
TMPY-06051 | SIRP alpha Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01573 | SIRP alpha Protein, Human, Recombinant (G75A, His) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-06052 | SIRP alpha V2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPK-01358 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01363 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00627 | SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01362 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00628 | SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00626 | SIRP alpha V8 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00307 | SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01356 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00625 | SIRP alpha V3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01357 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01364 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00611 | SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-02636 | SIRP alpha Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is BAA20376.1. | |||
TMPK-00609 | SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-05263 | SIRP alpha Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.7 kDa and the accession number is P78324-1. | |||
TMPY-06284 | SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 65.85 kDa and the accession number is P78324-1. | |||
TMPY-05126 | SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.8 kDa and the accession number is P78324-1. | |||
TMPK-00610 | SIRP alpha V2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-06053 | SIRP alpha V2 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.5 kDa and the accession number is AAH38510.1. | |||
TMPY-06248 | SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPY-06055 | SIRP alpha V8 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.6 kDa and the accession number is AAH38510.1. | |||
TMPY-06054 | SIRP alpha V8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPJ-00305 | SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His) | Cynomolgus | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPJ-00306 | SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPY-03572 | PTRH2 Protein, Human, Recombinant (His) | Human | E. coli |
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic... | |||
TMPY-04815 | C1 inhibitor Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
C1 inhibitor Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.7 kDa and the accession number is A6HMR4. | |||
TMPJ-00779 | TNF alpha Protein, Rabbit, Recombinant | Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty... | |||
TMPH-00761 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant | Neocosmosporum cucurbitae | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-03208 | IL-6 Protein, Rabbit, Recombinant (His) | Rabbit | P. pastoris (Yeast) |
IL-6 Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is Q9MZR1. | |||
TMPH-03215 | TNFSF4 Protein, Rabbit, Recombinant (hFc) | Rabbit | HEK293 Cells |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight ... | |||
TMPH-03206 | ITGB8 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b... | |||
TMPH-03216 | TNFSF4 Protein, Rabbit, Recombinant (His) | Rabbit | E. coli |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. TNFSF4 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular we... | |||
TMPH-03198 | MGAT1 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system wi... | |||
TMPY-00259 | IL-12B Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
IL-12B Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.1 kDa and the accession number is G1TBD7. | |||
TMPY-04663 | TrkA Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
TrkA Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is XP_008262512.1. | |||
TMPY-03634 | CD38 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
CD38 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9MZ03. | |||
TMPH-03204 | GHR Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon... | |||
TMPJ-00959 | B7-2 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071. | |||
TMPY-05287 | CD64A Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
CD64A Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is G1SJM8. | |||
TMPH-03210 | TFPI Protein, Rabbit, Recombinant (E. coli, His) | Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... | |||
TMPH-03199 | APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) | Rabbit | E. coli |
APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P18287. | |||
TMPY-02318 | Tissue Factor Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 Cells |
Tissue Factor Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.4 kDa and the accession number is P24055. | |||
TMPH-03202 | DAG1 Protein, Rabbit, Recombinant (His) | Rabbit | E. coli |
DAG1 Protein, Rabbit, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 73.5 kDa and the accession number is Q28685. | |||
TMPH-03213 | TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) | Rabbit | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPY-06738 | Ory c 3 Protein, Rabbit, Recombinant | Rabbit | P. pastoris (Yeast) |
Ory c 3 Protein, Rabbit, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 18.3 kDa. | |||
TMPH-02841 | Prohibitin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul... | |||
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L2000 | Inhibitor Library | 8328 compounds | |
A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L9410 | Covalent Inhibitor Library | 1920 compounds | |
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. | |||
L9400 | PPI Inhibitor Library | 485 compounds | |
A unique collection of 485 PPI-related compounds for drug screening; | |||
L2200 | Tyrosine Kinase Inhibitor Library | 1016 compounds | |
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; | |||
L1100 | Protease Inhibitor Library | 343 compounds | |
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L9100 | Phosphatase Inhibitor Library | 79 compounds | |
A collection of 79 phosphatase inhibitors with known activity; | |||
L2300 | Ion Channel Inhibitor Library | 931 compounds | |
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; | |||
DO2200 | Covalent inhibitors Library | 12000 compounds | |
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1600 | Kinase Inhibitor Library | 2700 compounds | |
A unique collection of 2700 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 263 compounds | |
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening. | |||
L3600 | Cytokine Inhibitor Library | 604 compounds | |
A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |
A collection of 575 highly selective inhibitors |