Powder: -20°C for 3 years
In solvent: -80°C for 2 years
1. Cucurbitacin IIA can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
Description | 1. Cucurbitacin IIA can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3. |
Synonyms | Dihydrocucurbitacin Q1, 葫芦素Iia, Curcurbitacin IIA, Hemslecin A |
Molecular Weight | 562.744 |
Formula | C32H50O8 |
CAS No. | 58546-34-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 91 mg/mL(161.7 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Cucurbitacin IIA 58546-34-2 凋亡 Apoptosis Survivin Inhibitor inhibit Curcurbitacin IIA Dihydrocucurbitacin Q1 Hemslecin A inhibitor