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Choline bitartrate

Catalog No. T6805 CAS 87-67-2

Synonyms: 2,3,4-trihydroxy-4-oxobutanoate, 2-hydroxyethyl(trimethyl)azanium

Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.

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Choline bitartrate, CAS 87-67-2

Pack Size	Availability	Price/USD
100 mg	In stock	$ 39.00
200 mg	In stock	$ 50.00
500 mg	In stock	$ 72.00
1 g	In stock	$ 105.00
1 mL * 10 mM (in DMSO)	In stock	$ 43.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcholine, a chemical that facilitates communication between the nerves and muscles.
In vitro	Choline is an essential nutrient needed for the structural integrity and signaling functions of cell membranes; for normal cholinergic neurotransmission; for normal muscle function; for lipid transport from liver; and it is the major source of methyl groups in the diet[3].
In vivo	Choline is critical for normal brain development. Choline deficiency has other health consequences—it is associated with liver and muscle damage and with an exaggerated plasma homocysteine rise after a methionine load. Elevated plasma homocysteine is an independent risk factor for cardiovascular disease and stroke in humans[3]. But choline bitartrate does not improve remembrance of spatial locations, declarative items, and verbal words[1].

Synonyms	2,3,4-trihydroxy-4-oxobutanoate, 2-hydroxyethyl(trimethyl)azanium
Molecular Weight	253.25
Formula	C5H14NO·C4H5O6
CAS No.	87-67-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 11 mg/mL (43.44 mM)

References and Literature

1. Lippelt DP, et al. PLoS One. 2016, 11(6):e0157714. 2. Schugar RC, et al. PLoS One. 2013, 8(8):e74806. 3. Zeisel SH, et al. Annu Rev Nutr. 2006, 26:229-50.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library Orally Active Compound Library Food Additive Library Pediatric Drug Library Natural Product Library Natural Product Library for HTS FDA-Approved & Pharmacopeia Drug Library Anti-Alzheimer's Disease Compound Library

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L-Hyoscyamine Choline chloride Varenicline dihydrochloride Mitotane PNU-120596 Pimethixene maleate suvn-911 Orphenadrine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Choline bitartrate 87-67-2 Neuroscience Others AChR 2,3,4-trihydroxy-4-oxobutanoate 2-hydroxyethyl(trimethyl)azanium Inhibitor Muscarinic acetylcholine receptor inhibit mAChR inhibitor

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