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TargetMol | Compound Library

FDA-Approved Kinase Inhibitor Library

Catalog No. L1610

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.

Targetmol's FDA-Approved Kinase Inhibitor Library contains 360 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors,PI 3-Kinase,CaM Kinase II,JAK,PKA,CDK,JNK,PKC,CKI II,MAPK,RAF,EGFR,MEK,SAPK,GSK,MLCK,Src-family,IKK,PDGFR,VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1610

FDA-Approved Kinase Inhibitor Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 360 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
  • All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
EGFR
VEGFR
NF-κB
c-Kit
Endogenous Metabolite
PDGFR
Antibacterial
Akt
ROS
ERK
JAK
c-Met/HGFR
FGFR
p38 MAPK
Antibiotic
Bcr-Abl
Parasite
Adrenergic Receptor
CDK
FLT
PI3K
AMPK
Src
PKC
mTOR
Tyrosine Kinases
Raf
ALK
MEK
Potassium Channel
JNK
Reactive Oxygen Species
Ferroptosis
Mitophagy
c-RET
Caspase
Calcium Channel
BTK
COX
Interleukin
Influenza Virus
AChR
ROS Kinase
Virus Protease
CaMK
Trk receptor
5-HT Receptor
Sodium Channel
Microtubule Associated
HIV Protease
PKA
ROCK
Dopamine Receptor
Antifungal
Topoisomerase
SARS-CoV
Bcl-2 Family
Nrf2
IκB/IKK
STAT
TNF
HER
Histamine Receptor
DNA/RNA Synthesis
TAM Receptor
GSK-3
PDE
HSV
IGF-1R
Ras
Serine/threonin kinase
Cytochromes P450
P-gp
Beta Amyloid
Tyrosinase
FAK
HCV Protease
Dehydrogenase
Adenosine Receptor
TOPK
HBV
PPAR
Wnt/beta-catenin
Serotonin Transporter
Mitochondrial Metabolism
Opioid Receptor
PAK
MMP
Aurora Kinase
Norepinephrine
MAPK
Antiviral
Prostaglandin Receptor
c-Fms
MDM-2/p53
Syk
HIF/HIF Prolyl-Hydroxylase
S1P Receptor
Kras
DHFR
ROR
Estrogen/progestogen Receptor
Ligands for Target Protein for PROTAC
Antioxidant
LPL Receptor
Reductase
NADPH
PERK
Tie-2
Glutathione Peroxidase
Serine Protease
TRP/TRPV Channel
CSF-1R
iGluR
IRE1
Hexokinase
Angiotensin-converting Enzyme (ACE)
GluR
ATP Citrate Lyase
HSP
TLR
Ephrin Receptor
FKBP
GABA Receptor
PLK
IRAK
ADC Cytotoxin
PGC-1α
Thyroid hormone receptor(THR)
Chloride channel
Proton pump
Carbonic Anhydrase
Transferase
DNA-PK
Integrin
Amino Acids and Derivatives
YAP
Arginase
RAAS
Necroptosis
gp120/CD4
Phosphatase
Progesterone Receptor
Melatonin Receptor
OCT
GNRH Receptor
PARP
Antifolate
Cell Cycle Arrest
Nucleoside Antimetabolite/Analog
IDO
Glucocorticoid Receptor
Immunology/Inflammation related
Adenylate cyclase
RIP kinase
LDL
GRK
MT Receptor
ABC Transporter
Antifection
Monoamine Transporter
PROTAC Linker
DPP-4
IL Receptor
Cholinesterase (ChE)
Chk
PAD
Xanthine Oxidase
Lipoxygenase
glycosidase
PANoptosis
DNA
Indoleamine 2,3-Dioxygenase (IDO)
Androgen Receptor
TGF-beta/Smad
Wee1
BCRP
ASK
Casein Kinase
ATM/ATR
GST
Reverse Transcriptase
Retinoid Receptor
HDAC
ribosome
Melanocortin Receptor
PDK
Gap Junction Protein
NOD
S6 Kinase
Sigma receptor
NOD-like Receptor (NLR)
PKM
NO Synthase
Ferroportin

Keywords