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TargetMol | Compound Library

FDA-Approved Kinase Inhibitor Library

Catalog No. L1610

Kinases are a class of enzymes that facilitates phosphorylation, by transferring phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules. A common group of kinases are the protein kinases, which act on specific proteins to phosphorylate them and alter their activity. Protein kinases are involved in a range of cell signaling and regulatory processes and play an important role in cell growth, metabolism, differentiation and apoptosis. Protein kinases have been associated with many diseases, including cancer, inflammatory diseases, cardiovascular diseases and neurological disorders. Therefore, targeting protein kinases has emerged as a promising therapeutic strategy for the treatment of related diseases.

Targetmol's FDA-Approved Kinase Inhibitor Library contains 325 marketed drugs that target kinases. These kinases include Insulin/IGF Receptors,PI 3-Kinase,CaM Kinase II,JAK,PKA,CDK,JNK,PKC,CKI II,MAPK,RAF,EGFR,MEK,SAPK,GSK,MLCK,Src-family,IKK,PDGFR,VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L1610

FDA-Approved Kinase Inhibitor Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 325 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
  • All compounds have undergone preclinical studies and clinical trials, approved for marketing by FDA, EMA, PMDA, etc., with proven biological activity and safety.
  • Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc.
  • NMR, HPLC/LCMS and other assay techniques to ensure the correct structure and high purity of the product and reduce false positives.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
VEGFR
EGFR
c-Kit
PDGFR
Endogenous Metabolite
NF-κB
Antibacterial
JAK
FGFR
c-Met/HGFR
ROS
FLT
Bcr-Abl
Akt
Parasite
Src
p38 MAPK
Antibiotic
Tyrosine Kinases
CDK
Adrenergic Receptor
PI3K
mTOR
PKC
Raf
ERK
ALK
Potassium Channel
AMPK
Reactive Oxygen Species
Mitophagy
c-RET
Ferroptosis
ROS Kinase
JNK
MEK
Influenza Virus
Microtubule Associated
Virus Protease
Trk receptor
HIV Protease
PKA
Calcium Channel
Interleukin
ROCK
CaMK
Sodium Channel
HER
SARS-CoV
IκB/IKK
AChR
COX
5-HT Receptor
Dopamine Receptor
Caspase
Topoisomerase
TAM Receptor
Bcl-2 Family
TNF
Nrf2
Antifungal
Histamine Receptor
GSK-3
DNA/RNA Synthesis
FAK
PDE
HSV
IGF-1R
c-Fms
Ras
Cytochromes P450
STAT
Serine/threonin kinase
P-gp
BTK
MAPK
Syk
HIF/HIF Prolyl-Hydroxylase
S1P Receptor
Dehydrogenase
NADPH
Beta Amyloid
Aurora Kinase
Adenosine Receptor
PAK
MDM-2/p53
HCV Protease
Kras
Antioxidant
HBV
ATP Citrate Lyase
ROR
Ligands for Target Protein for PROTAC
PPAR
Serine Protease
Mitochondrial Metabolism
Hexokinase
PLK
Reductase
Tie-2
TOPK
Serotonin Transporter
CSF-1R
HSP
Antiviral
LPL Receptor
Lipoxygenase
Ephrin Receptor
Glutathione Peroxidase
IRE1
Prostaglandin Receptor
FKBP
Tyrosinase
ADC Cytotoxin
Nucleoside Antimetabolite/Analog
iGluR
ABC Transporter
Monoamine Transporter
Cholinesterase (ChE)
GluR
DNA
Sirtuin
Casein Kinase
HDAC
Sigma receptor
Glucokinase
IL Receptor
Angiotensin-converting Enzyme (ACE)
MMP
Chk
Thyroid hormone receptor(THR)
DHFR
DNA-PK
Integrin
TGF-beta/Smad
Transferase
YAP
IFNAR
OCT
Hck
TRP/TRPV Channel
Glucocorticoid Receptor
IDO
GRK
MT Receptor
PDK
S6 Kinase
Estrogen/progestogen Receptor
Antifolate
PAD
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
gp120/CD4
Progesterone Receptor
PARP
GST
Gap Junction Protein
IRAK
Chloride channel
Proton pump
Phosphatase
Melatonin Receptor
LDL
Opioid Receptor
Xanthine Oxidase
Norepinephrine
TLR
Retinoid Receptor
NO Synthase
PKM
PGC-1α

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