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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T26828 | BIT225 | BIT 225,BIT-225 | |
BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows ... | |||
T3189 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor | Others |
B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. | |||
T22831 | Protein kinase inhibitor H-7 dihydrochloride | H-7 dihydrochloride | PKC |
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-... | |||
T22195 | CBFβ Inhibitor | 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine | DNA/RNA Synthesis |
CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1. | |||
T1804 | HPGDS inhibitor 1 | HPGDS-inhibitor-1 | PGE Synthase |
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM. | |||
T1383 | Bitoscanate | p-Phenylene diisothiocyanate,Biscomate,PDITC,1,4-Diisothiocyanatobenzene | Parasite |
Bitoscanate (PDITC) is used in the treatment of hookworms. | |||
T3593 | Src Inhibitor 1 | Src Kinase Inhibitor 1,Src-l1 | Src |
Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor. | |||
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. | |||
TP1015 | NFAT Inhibitor | VIVIT peptide | Others |
NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT. | |||
T6409 | ALK kinase inhibitor-1 | SAR348830 | Others |
SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase. | |||
T10629 | Btk inhibitor 2 | BGB-3111 analog | BTK |
Btk inhibitor 2 (BGB-3111 analog) is a BTK inhibitor. | |||
T15654 | Ketohexokinase inhibitor 1 | PF-06835919 | Others |
Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively). | |||
TP2310 | Autocamtide-2-related inhibitory peptide | CaMK , Autophagy | |
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | |||
TP1412 | RNAIII-inhibiting peptide TFA | RNAIII-inhibiting peptide(TFA) | Antibacterial |
RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis. | |||
TP1833L | SLLK, Control Peptide for TSP1 Inhibitor acetate | SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) | Others |
SLLK, Control Peptide for TSP1 Inhibitor acetate is a control peptide for LSKL. | |||
TP2008L | Lyn peptide inhibitor acetate | Lyn peptide inhibitor acetate(222018-18-0 free base) | IL Receptor |
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the bind... | |||
TP1921L1 | Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base) | CaMK , Autophagy | |
Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide. | |||
T83627 | Pim-1 kinase inhibitor 8 | Pim , PKC | |
Pim-1 kinase inhibitor 8 is a potent Pim-1 kinase inhibitor with anticancer activity and can effectively inhibit cell migration.Pim-1 kinase inhibitor 8 is cytotoxic to MCF-7 and HepG2 cells, and is a candidate compound ... | |||
T22081 | FBPase-1 inhibitor-1 | Fructose 1,6-bisphosphatase-1 Inhibitor | Others |
FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor. | |||
T50103 | NFAT Inhibitor-2 | Others | |
NFAT Inhibitor-2 is a compound used as a molecular building block. | |||
T35398 | MINA53 inhibitor (Compound 10) | Others | |
MINA53 inhibitor (Compound 10) is an inhibitor of MINA53. | |||
T4248 | T.cruzi Inhibitor (1350920-22-7(free base)) | Antibiotic | |
T.cruzi Inhibitor is a Trypanosoma cruzi inhibitor. | |||
T5831 | Selective PI3Kδ Inhibitor 1 | PI3K | |
Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM). | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T67830 | P38α inhibitor 3 | p38 MAPK | |
p38α inhibitor 3 is a inhibitor of the mitogen-activated protein kinase p38α that can block the effectiveness of myoblast differentiation. | |||
T8864 | Thymidylate Kinase Inhibitor, YMU1 | Others | |
YMU1 is a human thymidylate kinase (hTMPK) inhibitor. YMU1 stabilizes the conformation of ligand-induced degradation (LID) region of hTMPK and blocks the catalytic site or ATP-binding site. | |||
T9706 | BTK inhibitor 17 | BTK | |
BTK inhibitor 17 is a potent irreversible BTK inhibitor (IC50 = 2.1 nM). BTK inhibitor 17 can be used in rheumatoid arthritis studies. | |||
T9044 | SORT-PGRN interaction inhibitor 1 | Neurotensin Receptor | |
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM). | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T9725 | GSK-3β inhibitor 10 | Others | |
GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities. | |||
T6556 | K-Ras(G12C) inhibitor 9 | Raf | |
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T22043 | BCATc Inhibitor 2 | Others | |
BCATc Inhibitor 2 exhibited an IC50 of 0.8 microM in the hBCATc assays; it is an active and selective inhibitor. BCATc Inhibitor 2 also blocked calcium influx into neuronal cells following inhibition of glutamate uptake,... | |||
T67899 | Topoisomerase II inhibitor 13 | Topoisomerase | |
Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity. | |||
T9957 | LASV inhibitor 3.3 | Virus Protease | |
LASV inhibitor 3.3 is an inhibitor of Lassa fever virus (LASV) targeting lysosome-associated membrane protein 1 (LAMP1), a host factor that binds to the LASV glycoprotein (GP) during infection. | |||
T11190 | EMT inhibitor-1 | Wnt/beta-catenin | |
EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity. | |||
T2705 | Mutant EGFR inhibitor | EGFR | |
Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant. | |||
T37048 | MMP-3 Inhibitor | MMP | |
MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity. | |||
T67767 | HIF-1 inhibitor-4 | HIF-1 inhibitor-4 | HIF |
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level. | |||
T60358 | SEH inhibitor-7 | Epoxide Hydrolase | |
sEH inhibitor-7 is a soluble epoxide hydrolase (sEH) inhibitor that inhibits sEH in human and mouse with IC 50 s of 6.2 μM and 0.15 μM, respectively. sEH inhibitor-7 is associated with anti-inflammatory active molecules. | |||
T9393 | (E)-Akt inhibitor-IV | (E)-AKTIV,CS-1992 | Akt |
(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt. | |||
T8884 | HSMG-1 inhibitor 11j | PI3K , mTOR | |
hSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), ... | |||
T11279 | FGFR1/DDR2 inhibitor 1 | Discoidin Domain Receptor (DDR) , FGFR , Others | |
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively. | |||
T77502 | Wnt pathway inhibitor 3 | Wnt/beta-catenin , Adenylyl cyclase | |
Wnt pathway inhibitor 3 is a potent AC1 inhibitor with an IC50 value of 45 nM.Wnt pathway inhibitor 3 has antiproliferative activity and can be used in studies to ameliorate osteoarthritis in a mouse model of experimenta... | |||
T36316 | MTOR inhibitor-8 | mTOR-IN-8 | mTOR , Autophagy |
mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activity. mTOR inhibitor-8 inhibits the growth of A549 cells, which can be used to study non-small cell lung cancer. | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
T8472 | ERK1/2 inhibitor 2 | ASTX-029,ASTX029 | ERK |
ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity. | |||
T7265 | HSP27 inhibitor J2 | J2 | HSP |
HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function. | |||
T9939 | JMJD6 inhibitor WL12 | 2H-1-Benzopyran-2-one, 3-(3H-imidazo[4,5-c]pyridin-2-yl)-6-methyl-,ZINC6733033 | Others |
JMJD6 inhibitor WL12 (ZINC6733033) is a first-in-class JMJD6 inhibitor and was shown to be able to suppress JMJD6-dependent cancer cell proliferation including cervical and liver cancer cells, providing a small-molecule ... | |||
TP1890L1 | MLCK inhibitor peptide 18 acetate | MLCK inhibitor peptide 18 acetate(224579-74-2 free base) | Serine/threonin kinase |
MLCK inhibitor peptide 18 acetate is a selective competitive inhibitor of myosin light chain kinase (IC50 = 50 nM). Displays 4000-fold selectivity over CaM kinase II and does not inhibit PKA. Cell permeable. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1467 | Cucurbitacin E | CDK , Autophagy | |
Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cucurbitacin E has prevention of neurodegeneration, it has pot... | |||
T20550 | Thiobarbituric acid | NSC4733,NSC 4733,NSC-4733 | Antibacterial |
Thiobarbituric acid (NSC-4733) has Antibacterial Activity. | |||
TN1013 | Cucurbitacin D | IL Receptor , JNK , STAT | |
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. | |||
T3S1471 | Cucurbitacin IIA | Dihydrocucurbitacin Q1,Hemslecin A,Curcurbitacin IIA | Apoptosis , Survivin |
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a ... | |||
T6805 | Choline bitartrate | 2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium | Others , AChR |
Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcho... | |||
T5268 | D-Arabitol | D-Lyxitol | Others , Endogenous Metabolite |
D-Arabitol (D-Lyxitol) is a polyol. Polyols are sugar alcohols linked to the pentose phosphate pathway (PPP). Polyols occur in body fluids. It is thought that D-arabitol is a metabolic end-product in humans. | |||
T5853 | Rubitecan | RFS 2000,9-Nitrocamptothecin | Topoisomerase |
Rubitecan (9-Nitrocamptothecin) is a DNA topoisomerase I inhibitor. It inhibits DNA topoisomerase I and increases the fraction of supercoiled DNA in a cell-free assay in a concentration-dependent manner.Rubitecan is a se... | |||
T21066 | Norepinephrine bitartrate salt | Adrenergic Receptor | |
Norepinephrine bitartrate salt is an adrenergic neurotransmitter. | |||
TN1579 | Dihydrocucurbitacin B | 23,24-dihydrocucurbitacin B | IL Receptor , TNF , COX |
Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity. | |||
T4S1469 | Cucurbitacin IIb | Apoptosis , Others | |
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i... | |||
T3404 | Cucurbitacin B | Cuc B,DATISCACIN,Amarine | Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy |
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh... | |||
TQ0196 | Cucurbitacin I | NSC-521777,JSI-124,Elatericin B | JAK , STAT |
Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity. | |||
T1064 | Norepinephrine bitartrate monohydrate | Levophed,Noradrenaline bitartrate monohydrate | Endogenous Metabolite , Adrenergic Receptor , Autophagy |
Norepinephrine bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator. | |||
TQ0195 | 1,5-Anhydrosorbitol | Others , Endogenous Metabolite | |
1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food. | |||
TN2341 | Cucurbitacin Q1 | Others | |
Cucurbitacin Q1, a compound isolated from the fruit of Cucumis prophetarum, has been shown to be the pure trans component of cucurbitacin Q. | |||
T0332 | D-Sorbitol | Glucitol,Sorbitol,D-Glucitol | Others , Endogenous Metabolite |
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use... | |||
TN6313 | (19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol | ||
(19R)-5β,19-Epoxy-19-methoxycucurbita-6,23-diene-3β,25-diol is a natural product for research related to life sciences. The catalog number is TN6313 and the CAS number is 332950-28-4. | |||
TN2574 | 10-O-Ethylcannabitriol | Others | |
10-O-Ethylcannabitriol is a natural product from Cannabis sativa L. | |||
TN3074 | 5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol | Others | |
5,19-Epoxy-25-methoxycucurbita-6,23-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN3074 and the CAS number is 81910-39-6. | |||
TN6274 | 3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al | ||
3β-Hydroxy-7β,25-dimethoxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences. The catalog number is TN6274 and the CAS number is 85372-69-6. | |||
TN6956 | Cucurbitacin C | ||
Cucurbitacin C is a natural product. | |||
TN5949 | 5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol | ||
5β,19-Epoxy-19,25-dimethoxycucurbita-6,23-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN5949 and the CAS number is 85372-70-9. | |||
TN1533 | Cucurbitacin A | ROCK | |
Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/ROCK pathway and inhibition of LIM-Kinase. | |||
TN2887 | 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid | Phosphatase | |
(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. | |||
TN5993 | 16-Desoxycucurbitacin V | 3β,20S,25-Trihydroxycucurbita-5,23-dien-11-one | |
16-Desoxycucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5993 and the CAS number is 2081098-85-1. | |||
TN6333 | (19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19R,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6333 and the CAS number is 2281872-79-3. | |||
TN5974 | Cucurbitacin A 2-O-β-D-glucopyranoside | ||
Cucurbitacin A 2-O-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5974 and the CAS number is 1135141-76-2. | |||
TN6275 | 3,7,25-Trihydroxycucurbita-5,23-dien-19-al | 3β,7β,25-Trihydroxycucurbita-5,23-dien-19-al | |
3,7,25-Trihydroxycucurbita-5,23-dien-19-al is a natural product for research related to life sciences. The catalog number is TN6275 and the CAS number is 85372-65-2. | |||
TN3073 | 5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol | Others | |
5,19-Epoxy-19R,25-dimethoxycucurbita-6,23-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN3073 and the CAS number is 85372-72-1. | |||
TN6345 | (19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol | ||
(19S,23E)-5β,19-Epoxy-19-methoxycucurbita-6,23,25-trien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6345 and the CAS number is 874287-87-3. | |||
TN1534 | Cucurbitacin B 2-O-beta-D-glucoside | Others | |
Cucurbitacin B 2-o-α²-D-glucoside has anticancer activity. | |||
T83570 | (23E)-5b,19-epoxycucurbita-6,23,25(26)-triene-3b-ol | ||
(23E)-5β,19-epoxycucurbita-6,23,25(26)-triene-3β-ol, a cucurbitane triterpenoid, can be isolated from the seeds of Momordica charantia L. [1]. | |||
T4S1472 | Cucurbitacin S | ||
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities. | |||
TN5978 | 7β-Hydroxycucurbitacin B | ||
7β-Hydroxycucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5978 and the CAS number is 1135141-79-5. | |||
TN5995 | Cucurbitacin IIa 2-O-glucoside | Hemslecin A 2-O-glucoside | |
Cucurbitacin IIa 2-O-glucoside is a natural product for research related to life sciences. The catalog number is TN5995 and the CAS number is 77704-34-8. | |||
T81194 | Schibitubin I | ||
Schibitubin I, a lignin with neuroprotective activity, can be isolated from the fruits of Schisandra bicolor var. tuberculata [1]. | |||
TN6320 | (19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19S,23S)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6320 and the CAS number is 1616120-83-2. | |||
TN6305 | 3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside | ||
3β,7β,19-Trihydroxy-25-methoxycucurbita-5,23-diene 7-O-glucoside is a natural product for research related to life sciences. The catalog number is TN6305 and the CAS number is 81910-37-4. | |||
T82037 | Isocucurbitacin D | ||
Isocucurbitacin D is a compound recognized for its antitumor properties [1]. | |||
TN5990 | Cucurbitacin V | ||
Cucurbitacin V is a natural product for research related to life sciences. The catalog number is TN5990 and the CAS number is 152340-37-9. | |||
TN6332 | (19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol | ||
(19S,23R)-5β,19-Epoxy-19,23-dimethoxycucurbita-6,24-dien-3β-ol is a natural product for research related to life sciences. The catalog number is TN6332 and the CAS number is 1474062-47-9. | |||
T83578 | (19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol | ||
(19R,23E)-5b,19-Epoxy-19-ethoxycucurbita-6,23-diene-3b,25-diol, a cucurbitane-type triterpenoid, exhibited no activity against five cancer cell lines—MCF-7, HepG2, Du145, Colon205, and HL-60—when evaluated using the MTT ... | |||
T81690 | Neocucurbitacin A | STAT | |
Neocucurbitacin A (compound 7), a STAT3 inhibitor extracted from the pericarp of Aquilaria crassna, serves as a potential agent for anticancer research [1]. | |||
T6640 | Ribitol | Adonite,Adonitol | Others , Endogenous Metabolite |
Ribitol (Adonite) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis. | |||
TN1776 | Isocucurbitacin B | Others | |
Isocucurbitacin B has significant activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM. | |||
T82207 | Hexanorcucurbitacin D | ||
Hexanorcucurbitacin D, a cucurbitacin, is extractable from the roots of Trichosanthes cucumeroides and is utilized in cardiovascular disease (CVD) research [1]. | |||
TN3725 | Cucurbitadienol | ||
Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis... | |||
TN5988 | 16,25-Di-O-acetylcucurbitacin F | 16,25-O-Diacetyl-cucurbitane F,Cucurbitacin F 16,25-diacetate | |
16,25-Di-O-acetylcucurbitacin F is a natural product for research related to life sciences. The catalog number is TN5988 and the CAS number is 2062685-10-1. | |||
T83399 | 23,24-Dihydroisocucurbitacin D | ||
23,24-Dihydroisocucurbitacin D (compound 22) is a member of the cucurbitacins [1]. | |||
TN2909 | 3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al | Others | |
3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al is a natural product for research related to life sciences. The catalog number is TN2909 and the CAS number is 1446447-97-7. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02632 | SIRP alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06051 | SIRP alpha Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-01573 | SIRP alpha Protein, Human, Recombinant (G75A, His) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06052 | SIRP alpha V2 Protein, Human, Recombinant (His) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPK-01358 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01363 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00627 | SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00611 | SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01362 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00626 | SIRP alpha V8 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00628 | SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01356 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01357 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01364 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00307 | SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-00625 | SIRP alpha V3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-02636 | SIRP alpha Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPK-00609 | SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-06284 | SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-05263 | SIRP alpha Protein, Human, Recombinant (mFc) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-05126 | SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPK-00610 | SIRP alpha V2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPY-06053 | SIRP alpha V2 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06248 | SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06055 | SIRP alpha V8 Protein, Human, Recombinant (mFc) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06054 | SIRP alpha V8 Protein, Human, Recombinant (His) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPJ-00305 | SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His) | Cynomolgus | Human Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPJ-00306 | SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre... | |||
TMPY-03572 | PTRH2 Protein, Human, Recombinant (His) | Human | E. coli |
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic... | |||
TMPY-04815 | C1 inhibitor Protein, Rat, Recombinant (His) | Rat | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s... | |||
TMPJ-00779 | TNF alpha Protein, Rabbit, Recombinant | Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty... | |||
TMPH-03204 | GHR Protein, Rabbit, Recombinant (His & Myc) | Rabbit | in vitro E. coli expression system |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormon... | |||
TMPH-03210 | TFPI Protein, Rabbit, Recombinant (E. coli, His) | Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... | |||
TMPH-03208 | IL-6 Protein, Rabbit, Recombinant (His) | Rabbit | Yeast |
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign... | |||
TMPH-03216 | TNFSF4 Protein, Rabbit, Recombinant (His) | Rabbit | E. coli |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. | |||
TMPH-00761 | Cutinase Protein, Fusarium solani subsp. Cucurbitae, Recombinant | Neocosmosporum cucurbitae | E. coli |
Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of the fungal infe... | |||
TMPH-03199 | APOE Protein, Rabbit, Recombinant (His & Myc & SUMO) | Rabbit | E. coli |
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plas... | |||
TMPH-03213 | TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) | Rabbit | E. coli |
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contra... | |||
TMPH-03202 | DAG1 Protein, Rabbit, Recombinant (His) | Rabbit | E. coli |
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epi... | |||
TMPH-03215 | TNFSF4 Protein, Rabbit, Recombinant (hFc) | Rabbit | HEK293 |
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. | |||
TMPH-03206 | ITGB8 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b... | |||
TMPH-03198 | MGAT1 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. | |||
TMPY-05287 | CD64A Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
CD64A Protein, Rabbit, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 32.2 kDa. Accession number: G1SJM8 | |||
TMPY-04663 | TrkA Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot... | |||
TMPY-03634 | CD38 Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-02318 | Tissue Factor Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Tissue factor (TF), also known as coagulation factor III, F3, and CD142, is a single-pass type I membrane protein which belongs to the tissue factor family. Tissue factor is one of the proteins that participate in hemost... | |||
TMPY-00259 | IL-12B Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts... | |||
TMPJ-00959 | B7-2 Protein, Rabbit, Recombinant (His) | Rabbit | Human Cells |
T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm... | |||
TMPY-01183 | C1 inhibitor Protein, Human, Recombinant (His) | Human | HEK293 |
Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s... | |||
TMPY-06738 | Ory c 3 Protein, Rabbit, Recombinant | Rabbit | P. pastoris |
Ory c 3 Protein, Rabbit, Recombinant is expressed in P. pastoris. The predicted molecular weight is 18.3 kDa. | |||
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L2000 | Inhibitor Library | 8328 compounds | |
A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L9410 | Covalent Inhibitor Library | 1920 compounds | |
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc. | |||
L9400 | PPI Inhibitor Library | 485 compounds | |
A unique collection of 485 PPI-related compounds for drug screening; | |||
L2200 | Tyrosine Kinase Inhibitor Library | 1016 compounds | |
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; | |||
L1100 | Protease Inhibitor Library | 343 compounds | |
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L9100 | Phosphatase Inhibitor Library | 79 compounds | |
A collection of 79 phosphatase inhibitors with known activity; | |||
L2300 | Ion Channel Inhibitor Library | 931 compounds | |
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; | |||
DO2200 | Covalent inhibitors Library | 12000 compounds | |
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L1400 | MAPK Inhibitor Library | 365 compounds | |
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; | |||
L1600 | Kinase Inhibitor Library | 2700 compounds | |
A unique collection of 2700 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases; | |||
L1610 | FDA-Approved Kinase Inhibitor Library | 263 compounds | |
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening. | |||
L3600 | Cytokine Inhibitor Library | 604 compounds | |
A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; | |||
L2010 | Highly Selective Inhibitor Library | 575 compounds | |
A collection of 575 highly selective inhibitors |