Search Result

Search Results for " ifn "

Targets

IFNAR Others IFNAR

118

Compounds

Natural Products

303

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T11630	IFN alpha-IFNAR-IN-1 hydrochloride		Others , IFNAR
	IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.		Others , IFNAR
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN ind...
T11630L	IFN alpha-IFNAR-IN-1		Others
	IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM).		Others
TP1117	IFN-α Receptor Recognition Peptide 1	IRRP1
	IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.
T76637	IFN-γ Antagonist 1
	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells, demonstrating an IC50 of approximately 35 μM. This compoun...
T76638	IFN-γ Antagonist 1 acetate
	IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate, an interferon γ (IFN γ) antagonist, effectively inhibits the expression of HLR/DR antigen in Colon 205 cells induced by IFN-γ, with an inhibition concentration (IC 50)...
T83147	Albinterferon alfa-2B	alb-IFN
	Albinterferon alfa-2B (alb-IFN), a recombinant protein, comprises interferon alfa-2b conjugated to human albumin and is utilized in the study of chronic hepatitis C [1].
T78262	Anti-Mouse IFN gamma Antibody (H22)		IFNAR
	Anti-Mouse IFN Gamma Antibody is a host Armenian Hamster-derived anti-mouse IFN gamma immunoglobulin G (IgG) inhibitor.		IFNAR
T81259	Rontalizumab	RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody
	Rontalizumab, a humanized IgG1 monoclonal antibody, targets IFN-α and is utilized in research on systemic lupus erythematosus[1].
T9043	AS1810722		P450 , STAT
	AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate f...		P450 , STAT
T21694	(R)-Lisofylline	(R)-Lisophylline	STAT
	(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...		STAT
T12933	SM-276001		TLR , COX
	SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.		TLR , COX
T8692	(Rac)-Benpyrine		TNF
	(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.		TNF
T9616	PD-1/PD-L1-IN-10		PD-1/PD-L1
	PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.		PD-1/PD-L1
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T83628	TNF/IFNγ-IN-1		Antioxidant , TNF , COX
	TNF/IFNγ-IN-1 (TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFNγ-IN-1 has potential antioxidant and anti-inflammatory activities for neurodegenerative diseases such as Alzheimer.		Antioxidant , TNF , COX
T78263	Anti-Mouse IFNAR1 Antibody (MAR1-5A3)		IFNAR
	Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. It is of the Mouse IgG1 kappa isotype and a corresponding i...		IFNAR
T0867	Bufexamac	Bufexamic acid	COX , HDAC
	Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.		COX , HDAC
T19675	SM360320	CL-087,SM 360320,CL 087,1V136,SM-360320,CL087	TLR
	SM360320 (CL-087) is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity. SM360320 can be used for ...		TLR
T22142	RO8191	RO4948191,CDM-3008	HCV Protease , HBV , JAK , IFNAR , STAT
	RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.		HCV Protease , HBV , JAK , IFNAR , STAT
T13736	Interferon receptor inducer-1		IFNAR
	Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.		IFNAR
T76742	Emapalumab	NI-0501	COX
	Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab ha...		COX
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride	N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others , Proteasome , COX
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib...		Others , Proteasome , COX
T73486	RIG012		Others
	RIG012 is a potent RIG-I inhibitor with an IC50 value of 0.71 μM measured by NADH-coupled ATPase.RIG012 inhibited the expression of IFN-β and ISG hRsad2.		Others
T77432	Anifrolumab	MDX-1333,MEDI-546	IFNAR
	Anifrolumab（MEDI-546） is a potent type I interferon (IFN) receptor antagonist, a human monoclonal antibody that targets IFN.Anifrolumab inhibits the activity of type I interferon and is used for the prevention and treatm...		IFNAR
T27034	CL075	3M002,CL-075	NF-κB , TLR , MyD88
	CL075 (3M002) is a selective TLR8 agonist.CL075 has immunomodulatory activity by triggering the MyD88-dependent signaling pathway, activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I i...		NF-κB , TLR , MyD88
T36113	Cobaltic Protoporphyrin IX chloride	Protoporphyrin IX cobaltic chloride	Autophagy
	Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a pote...		Autophagy
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T4403	AX-024 hydrochloride	AX-024 HCl	IL Receptor , TNF , COX , IFNAR , Interleukin
	AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.		IL Receptor , TNF , COX , IFNAR , Interleukin
T76691	Monalizumab		IFNAR , Chk
	Monalizumab is a novel immune checkpoint inhibitor targeting natural killer cell population 2A (NKG2A). Monalizumab is a humanized monoclonal antibody against NKG2A that induces IFN-γ production, thereby activating natur...		IFNAR , Chk
T14687	Deucravacitinib	BMS-986165	Tyrosine Kinases , JAK , IFNAR , Interleukin
	Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...		Tyrosine Kinases , JAK , IFNAR , Interleukin
T2168	2-(1,8-naphthyridin-2-yl)phenol		STAT
	2-NP is a STAT1 enhancer.		STAT
T13063	T6167923		MyD88
	T6167923 is a potent, selective inhibitor of MyD88-dependent signaling pathways. It achieves this by directly binding to the Toll/IL1 receptor (TIR) domain of MyD88, preventing MyD88 homodimer formation. Subsequently, T6...		MyD88
T5988	Dimethyl biphenyl-4,4'-dicarboxylate	Biphenyl dimethyl dicarboxylate	Others
	Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis.		Others
T0097	MRT67307	MRT67307 HCl	IκB/IKK , Autophagy
	Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...		IκB/IKK , Autophagy
T5521	Bropirimine	U-54461	TLR
	Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.		TLR
T11482	GSK2245035		Others
	GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine p...		Others
T64280	ODN 2216
	ODN 2216 is a TLR9 (toll-like receptor 9) ligand or agonist that induces the production of large amounts of IFN-α and IFN-β. ODN 2216 can induce IFN-α using pDC (plasma cell-like DC) and IL-12 (p40) using DC (dendritic c...
T76930	Bifarcept
	Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.
T28004	MDK8228	PF-CBP/BRD4,MDK-8228,MDK 8228
	MDK8228 is an inhibitor of CBP/p300 and BRD4 bromodomain. MDK8228 downregulates IL-6, IL-ß and IFN-ß in macrophages.
T23813	Bozepinib
	Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.
T38162	STING18
	STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β productio...
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sens...
T36169	15-LOX-1 inhibitor 1
	9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and I...
T70965	GSK-2245035 maleate
	GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.
T76808	Fontolizumab
	Fontolizumab (HuZAF) is a humanized monoclonal antibody targeting IFN-gamma, functioning as an immunosuppressive agent. It is utilized in the study of Crohn’s disease [1].
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS ...
T79189	1-Isopropyltryptophan	1-IsoPT	Indoleamine 2,3-Dioxygenase (IDO)
	1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].		Indoleamine 2,3-Dioxygenase (IDO)
T16570	Pralnacasan	VX-740,HMR 3480	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ...		Others
T64279	ODN 21158
	ODN 21158 is a potent, non-cytotoxic inhibitor of G-modified TLR3 and TLR9. ODN 21158 dose-dependently inhibits IFN-α secretion.

Compounds

IFN alpha-IFNAR-IN-1 hydrochloride

T11630

Synonym:

Target: Others, IFNAR

IFN alpha-IFNAR-IN-1

T11630L

Synonym:

Target: Others

IFN-α Receptor Recognition Peptide 1

IFN-γ Antagonist 1 acetate

T76638

Synonym:

Target:

Albinterferon alfa-2B

T83147

Synonym: alb-IFN

Target:

Anti-Mouse IFN gamma Antibody (H22)

Synonym: RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody

Synonym: (R)-Lisophylline

Target: GPR, Potassium Channel

TNF/IFNγ-IN-1

T83628

Synonym:

Target: Antioxidant, TNF, COX

Anti-Mouse IFNAR1 Antibody (MAR1-5A3)

Synonym: Bufexamic acid

Target: COX, HDAC

SM360320

T19675

Synonym: CL-087,SM 360320,CL 087,1V136,SM-360320,CL087

Target: TLR

RO8191

T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Interferon receptor inducer-1

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

T16169

Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Target: Others, Proteasome, COX

Synonym: MDX-1333,MEDI-546

Target: IFNAR

CL075

T27034

Synonym: 3M002,CL-075

Target: NF-κB, TLR, MyD88

Cobaltic Protoporphyrin IX chloride

T36113

Synonym: Protoporphyrin IX cobaltic chloride

Target: Autophagy

Vadimezan

T6273

Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

AX-024 hydrochloride

T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

2-(1,8-naphthyridin-2-yl)phenol

Dimethyl biphenyl-4,4'-dicarboxylate

T5988

Synonym: Biphenyl dimethyl dicarboxylate

Target: Others

MRT67307

T0097

Synonym: MRT67307 HCl

Target: IκB/IKK, Autophagy

Synonym: PF-CBP/BRD4,MDK-8228,MDK 8228

1-Isopropyltryptophan

T79189

Synonym: 1-IsoPT

Target: Indoleamine 2,3-Dioxygenase (IDO)

Pralnacasan

T16570

Synonym: VX-740,HMR 3480

Cat No.	Product Name	Synonyms	Targets
TN2539	1beta-Hydroxyalantolactone		IL Receptor , TNF
	1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...		IL Receptor , TNF
T5773	Moslosooflavone	5-hydroxy-7,8-dimethoxyflavone	NF-κB , Reactive Oxygen Species
	Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activi...		NF-κB , Reactive Oxygen Species
T5681	ETHYL CAFFEATE	ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB , COX , PGE Synthase , NO Synthase
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...		NF-κB , COX , PGE Synthase , NO Synthase
T37280	PE(18:1(9Z)/0:0)		Endogenous Metabolite
	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ...		Endogenous Metabolite
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T14854	Caerulomycin A	Cerulomycin,Caerulomycin	Antifungal
	Caerulomycin A (Caerulomycin) (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antif...		Antifungal
T6677	Sophocarpine		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
TN6366	Lupinalbin A
	Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokine...
TN5233	Villosin		Others
	Villosin exhibits potent cytotoxic activity , it may be used as a potential lead molecule for antitumor therapeutic development. Villosin shows inhibitory effects against nitric oxide production in LPS and IFN-γ-induced ...		Others
TN4959	Schizandriside		Prostaglandin Receptor
	Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. It shows significant cyt...		Prostaglandin Receptor
TN4334	Isotaxiresinol		TNF
	Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis indu...		TNF
T35895	Ingenol 3,20-dibenzoate
	Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the partic...

Natural Products

1beta-Hydroxyalantolactone

TN2539

Synonym:

Target: IL Receptor, TNF

Moslosooflavone

T5773

Synonym: 5-hydroxy-7,8-dimethoxyflavone

Target: NF-κB, Reactive Oxygen Species

ETHYL CAFFEATE

T5681

Synonym: ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

PE(18:1(9Z)/0:0)

T37280

Synonym:

Target: Endogenous Metabolite

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Ginsenoside F3

T3829

Synonym:

Target: Others, IFNAR, Interleukin

Jaceosidin

T3824

Synonym:

Target: Apoptosis, BCL, COX, UGT

Caerulomycin A

T14854

Synonym: Cerulomycin,Caerulomycin

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Target: Prostaglandin Receptor

Ingenol 3,20-dibenzoate

T35895

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03356	IFN gamma Protein, Mouse, Recombinant	Mouse	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-01714	IFN gamma Protein, Human, Recombinant	Human	CHO
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03467	IFN-beta Protein, Mouse, Recombinant	Mouse	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli)	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03072	IFN-omega Protein, Human, Recombinant (His)	Human	HEK293
	IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide s...
TMPK-00047	IFN gamma Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPY-03145	IFN-beta Protein, Human, Recombinant	Human	CHO
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPJ-00746	IFN-alpha 2b/IFNA2 Protein, Human, Recombinant	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ...
TMPJ-00745	IFN-alpha 2a/IFNA2 Protein, Human, Recombinant	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common ...
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-02827	IFN gamma Protein, Rat, Recombinant (hFc)	Rat	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-04578	Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)	Human	Yeast
	IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, par...
TMPY-02323	IFN gamma Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-02322	IFN gamma Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-00638	Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites...
TMPY-00833	IFN-omega Protein, Human, Recombinant (hFc)	Human	HEK293
	IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide s...
TMPY-02515	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a c...
TMPY-02566	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interferon, alpha 4 (IFNA4) belongs to the alpha/beta interferon family. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 an...
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPK-00048	IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experi...
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPY-00527	IFN gamma Protein, Rhesus, Recombinant	Rhesus	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-04191	IFN gamma Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-03664	IFN gamma Protein, Ferret, Recombinant (His)	Ferret	HEK293
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPJ-00747	IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant	Mouse	E. coli
	At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a c...
TMPY-02355	IFNGR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)	Human	Human Cells
	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interfer...
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc)	Rhesus	HEK293
	Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras...
TMPY-00265	Interferon alpha 2/IFNA2 Protein, Human, Recombinant	Human	Yeast
	IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interfero...
TMPY-03320	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 46.4 kDa. Accession number: G7NFW4
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-03375	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 20.8 kDa. Accession number: G7NFW4
TMPY-02347	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 47.5 kDa. Accession number: Q80SU4
TMPY-03891	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 20.5 kDa. Accession number: Q80SU4
TMPK-00342	IFNAR1 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00325	IFNAR1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00637	IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)	Cynomolgus	HEK293
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated...
TMPK-00326	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00343	IFNAR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00889	IFNAR2 Protein, Human, Recombinant (aa 27-243, His)	Human	HEK293
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated...
TMPY-00830	Interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepat...
TMPY-04855	Interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)	Human	Yeast
	Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepat...
TMPJ-01371	Limitin Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin...
TMPH-00374	IFN-beta Protein, Chicken, Recombinant (His)	Chicken	E. coli
	Has antiviral activities.
TMPH-00373	IFN gamma Protein, Chicken, Recombinant (GST)	Chicken	E. coli
	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproli...
TMPY-03648	Interferon alpha B/IFNA8 Protein, Human, Recombinant	Human	HEK293
	Interferon alpha-B, also known as IFNA8, belongs to the alpha/beta interferon family. Interferons are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites...
TMPY-04841	Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)	Human	Yeast
	Interferon alpha-7(IFNA7) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a c...
TMPH-03495	IFN gamma Protein, Sheep, Recombinant (His)	Sheep	Yeast
	Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentatio...
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IFN gamma Protein, Mouse, Recombinant

TMPY-03356

Species: Mouse

Expression System: HEK293

IFN gamma Protein, Human, Recombinant

TMPY-01714

Species: Human

Expression System: CHO

IFN-beta Protein, Mouse, Recombinant

TMPY-03467

Species: Mouse

Expression System: HEK293

IFN gamma Protein, Human, Recombinant (E. coli)

TMPY-06983

Species: Human

Expression System: E. coli

IFN-omega Protein, Human, Recombinant (His)

TMPY-03072

Species: Human

Expression System: HEK293

IFN gamma Protein, Human, Recombinant (His & Avi)

TMPK-00047

Species: Human

Expression System: HEK293

IFN-beta Protein, Human, Recombinant

TMPY-03145

Species: Human

Expression System: CHO

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

TMPJ-00746

Species: Human

Expression System: E. coli

IFN-alpha 2a/IFNA2 Protein, Human, Recombinant

TMPJ-00745

Species: Human

Expression System: E. coli

IFN-beta Protein, Human, Recombinant (hFc)

TMPY-00831

Species: Human

Expression System: HEK293

IFN gamma Protein, Rat, Recombinant (hFc)

TMPY-02827

Species: Rat

Expression System: HEK293

Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

TMPY-04578

Species: Human

Expression System: Yeast

IFN gamma Protein, Mouse, Recombinant (His)

TMPY-02323

Species: Mouse

Expression System: HEK293

IFN gamma Protein, Mouse, Recombinant (hFc)

TMPY-02322

Species: Mouse

Expression System: HEK293

Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

TMPY-00638

Species: Human

Expression System: HEK293

IFN-omega Protein, Human, Recombinant (hFc)

TMPY-00833

Species: Human

Expression System: HEK293

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

TMPY-02515

Species: Human

Expression System: HEK293

Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)

TMPY-02566

Species: Human

Expression System: Baculovirus-Insect Cells

IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

TMPK-00074

Species: Mouse

Expression System: HEK293

IFN-beta Protein, Mouse, Recombinant (hFc)

TMPY-02456

Species: Mouse

Expression System: HEK293

IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00048

Species: Human

Expression System: HEK293

IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)

TMPK-00075

Species: Human

Expression System: HEK293

IFN gamma Protein, Rhesus, Recombinant

TMPY-00527

Species: Rhesus

Expression System: E. coli

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

TMPY-04799

Species: Human

Expression System: HEK293

IFN gamma Protein, Rhesus, Recombinant (His)

TMPY-04191

Species: Rhesus

Expression System: HEK293

IFN gamma Protein, Ferret, Recombinant (His)

TMPY-03664

Species: Ferret

Expression System: HEK293

IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant

TMPJ-00747

Species: Mouse

Expression System: E. coli

IFNGR1 Protein, Mouse, Recombinant (His)

TMPY-02355

Species: Mouse

Expression System: HEK293

IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

TMPJ-00780

Species: Human

Expression System: Human Cells

IFN-beta Protein, Rhesus, Recombinant (mFc)

TMPY-03828

Species: Rhesus

Expression System: HEK293

Interferon alpha 2/IFNA2 Protein, Human, Recombinant

TMPY-00265

Species: Human

Expression System: Yeast

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)

TMPY-03320

Species: Cynomolgus

Expression System: HEK293

IFNAR1 Protein, Human, Recombinant (His)

TMPY-02647

Species: Human

Expression System: HEK293

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)

TMPY-03375

Species: Cynomolgus

Expression System: HEK293

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)

TMPY-02347

Species: Mouse

Expression System: HEK293

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)

TMPY-03891

Species: Mouse

Expression System: HEK293

IFNAR1 Protein, Mouse, Recombinant (His & Avi)

TMPK-00342

Species: Mouse

Expression System: HEK293

IFNAR1 Protein, Human, Recombinant (His & Avi)

TMPK-00325

Species: Human

Expression System: HEK293

IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

TMPK-00637

Species: Cynomolgus

Expression System: HEK293

IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00326

Species: Human

Expression System: HEK293

IFNAR1 Protein, Mouse, Recombinant (hFc)

TMPK-00343

Species: Mouse

Expression System: HEK293

IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

TMPK-00889

Species: Human

Expression System: HEK293

interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc)

TMPY-00830

Species: Human

Expression System: HEK293

interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)

TMPY-04855

Species: Human

Expression System: Yeast

Limitin Protein, Mouse, Recombinant (His)

TMPJ-01371

Species: Mouse

Expression System: Human Cells

IFN-beta Protein, Chicken, Recombinant (His)

TMPH-00374

Species: Chicken

Expression System: E. coli

IFN gamma Protein, Chicken, Recombinant (GST)

TMPH-00373

Species: Chicken

Expression System: E. coli

Interferon alpha B/IFNA8 Protein, Human, Recombinant

TMPY-03648

Species: Human

Expression System: HEK293

Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)

TMPY-04841

Species: Human

Expression System: Yeast

IFN gamma Protein, Sheep, Recombinant (His)

TMPH-03495

Species: Sheep

Expression System: Yeast

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Cat No.	Product Name
L3600	Cytokine Inhibitor Library		604 compounds
	A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;

Libraries

Cytokine Inhibitor Library

L3600

Compounds: 604