Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis.
Pack Size | Availability | Price/USD | Quantity |
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100 mg | In stock | $ 39.00 |
Description | Dimethyl biphenyl-4,4'-dicarboxylate (Biphenyl dimethyl dicarboxylate) is a planar biphenyldicarboxylic acid ester used as a hepatoprotectant in the treatment of chronic hepatitis. |
In vitro | Dimethyl biphenyl-4,4'-dicarboxylate(DDB) (200 ug/10(6) cells) efficiently protected the hepatocytes against carbon tetrachloride (10 mM) and D-galactosamine (1 mM) induced damages.?Membrane lipid peroxidation (malondialdehyde, MDA) formation and Glutamic Pyruvic Transaminase (GPT) released from the hepatocytes were markedly decreased.?The damage of the cell surfaces of the hepatocytes were also reduced as seen under a scanning electron microscope (SEM)[1]. |
In vivo | Pretreatment with DDB (300 mg/kg) orally could ameliorate the reduction of liver glycogen and blood glucose caused by injection of D-gal (800 mg/kg i. p) in mice.?When normal rats received 300 mg/kg of DDB once daily for 10 days, free ribosomal protein and RNA in the liver increased significantly[1]. |
Synonyms | Biphenyl dimethyl dicarboxylate |
Molecular Weight | 270.28 |
Formula | C16H14O4 |
CAS No. | 792-74-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 2.5 mM
DMSO: Insoluble
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