Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 36.00 | |
100 mg | In stock | $ 48.00 | |
200 mg | In stock | $ 63.00 | |
500 mg | In stock | $ 87.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 30.00 |
Description | Bufexamac (Bufexamic acid) is a COX inhibitor for IFN-α release with anti-inflammatory, analgesic, and antipyretic action. |
Targets&IC50 | IFN-α:8.9 μM |
In vitro | Bufexamac is a specific inhibitor of class IIB histone deacetylases (HDAC6 and HDAC10). Treatment of peripheral blood mononuclear cells with bufexamac inhibits the secretion of IFN-α. [1] Bufexamac is a frequent and relevant contact sensitizer. Bufexamac is a non-steroidal anti-inflammatory drug. [2] |
Synonyms | Bufexamic acid |
Molecular Weight | 223.27 |
Formula | C12H17NO3 |
CAS No. | 2438-72-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 3 mg/mL (13.43 mM)
DMSO: 42 mg/mL (188.1 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Bufexamac 2438-72-4 Chromatin/Epigenetic DNA Damage/DNA Repair Immunology/Inflammation Neuroscience COX HDAC Histone deacetylases inhibit Bufexamic acid Inhibitor inhibitor