Search Result

Search Results for " γ-2 "

Compounds

Natural Products

345

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1532	γ-2-MSH (41-58), amide
	Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cel...
T19105	2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol		Others
	2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride.		Others
T33519	MTOB	α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid	Others
	MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...		Others
T8887	2'MeO6MF		GABA Receptor
	2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors.It offers neuroprotection and improved functional recovery and dampens the stroke-induced inflammatory response...		GABA Receptor
T63221	PI3Kδ/γ-IN-2
	PI3Kδ/γ-IN-2 is a potent, orally bioavailable dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 4.3 nM) with potential for use in anti-B-cell malignancy studies.
T14983	Clomethiazole	Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE	P450 , GABA Receptor
	Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C...		P450 , GABA Receptor
T15184	E 2012		Gamma-secretase
	E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induc...		Gamma-secretase
T11307	Fluxametamide		GABA Receptor
	Fluxametamide is a novel isoxazoline insecticide that acts via distinctive antagonism of insect ligand-gated chloride channels, acts as an antagonist of GABA- and glutamate-gated chloride channels(IC50 of 1.95 nM and 225...		GABA Receptor
T15212	Emamectin Benzoate	MK-244	Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
	Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T10115	3-Nitrocoumarin	3-nitrochromen-2-one	Phospholipase
	3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.		Phospholipase
T5531	GSK-4716		Estrogen Receptor/ERR
	GSK4716 is an ERRβ/γ agonist (IC50 = 2 µM) that can activate the receptor with similar potency as the protein ligand		Estrogen Receptor/ERR
T15440	GSK376501A		PPAR
	GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.		PPAR
T9641	Aβ42-IN-2		Gamma-secretase
	Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].		Gamma-secretase
T63898	Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-		PPAR
	Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-p...		PPAR
T6524	GW0742	GW610742	PPAR
	GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).		PPAR
T21587	Muraglitazar	Pargluva,BMS-298585	PPAR
	Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPARα and PPARγ with EC50 of 320 nM and 110 nM r...		PPAR
T6143	PI-103	PI103,PI 103	Apoptosis , DNA-PK , PI3K , mTOR , Autophagy
	PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).		Apoptosis , DNA-PK , PI3K , mTOR , Autophagy
T6249	Avagacestat	BMS-708163	Gamma-secretase
	Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.		Gamma-secretase
TN7044	S-(4-Hydroxybenzyl)glutathione		GluR
	L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia ela...		GluR
T15411	GPNA hydrochloride		Apoptosis , Others
	GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT)....		Apoptosis , Others
T2168	2-(1,8-naphthyridin-2-yl)phenol		STAT
	2-NP is a STAT1 enhancer.		STAT
T14680	BMS-906024	Osugacestat,AL-101,BM-0018	Gamma-secretase
	BMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-...		Gamma-secretase
T14214	AMG 511		PI3K
	AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG...		PI3K
T14313	Apricitabine	AVX754,SPD754	HIV Protease , DNA/RNA Synthesis
	Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (dOTC) . Apricitabine inhibits DNA polymerase α, β a...		HIV Protease , DNA/RNA Synthesis
T1706	4-Hydroxy-3-nitrophenylacetic acid		Others
	4-Hydroxy-3-nitrophenylacetic acid is a small molecular drug, active in Ig heavy chain V-I region and Ig gamma-2 chain C region.		Others
T16022	Arhalofenate	JNJ 39659100,MBX 102	PPAR
	Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.		PPAR
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T1861	Omipalisib	GSK458,GSK2126458	PI3K , mTOR , Autophagy
	Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.		PI3K , mTOR , Autophagy
T2357	GSK1059615	GSK 1059615,GSK-1059615	Apoptosis , PI3K , mTOR
	GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.		Apoptosis , PI3K , mTOR
T76870	Narsoplimab	OMS 721	SARS-CoV
	Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac...		SARS-CoV
T3211	Midostaurin	N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251	Others , PKC
	PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel...		Others , PKC
T22070	DBIBB		LPA Receptor
	DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma ra...		LPA Receptor
T35454	γ-Glu-Cys (ammonium salt)
	γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelati...
T33415	MK 0767	MK0767,MK-0767
	MK 0767 is a dual peroxisome proliferator-activated receptor (PPAR) α/γ agonist that has been investigated as a potential treatment for type 2 diabetes and dyslipidemia.
T63149	LY-411575 (isomer 2)
	LY-411575 isomer 2 is an isomer of LY411575. LY411575 is a potent inhibitor of γ-secretase.
T10596	BR102375		Others
	BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.		Others
T80681	γ-Glutamylserine TFA	γ-Glu-Ser TFA	Calcium Channel
	γ-Glutamylserine TFA (γ-Glu-Ser TFA) serves as a calcium receptor activator and is utilized in research focused on Parkinson's disease, diabetes, and obesity [1] [2].		Calcium Channel
T11904	LY-411575 isomer 2		Others
	LY-411575 isomer 2 is a potent γ-secretase inhibitor. LY-411575 isomer 2 is an isomer of LY411575.		Others
T33407	MitoEbselen-2 chloride	MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2
	MitoEbselen-2 is a radiation mitigator which reduces lipid hydroperoxides and prevents apoptotic cell death. When administered 24 hours postirradiation, MitoEbselen-2 was shown to increase the survival of mice exposed to...
T79929	L-Methionine γ-lyase	Methionine lyase
	L-Methionine γ-lyase (Methionine lyase), a multifaceted enzyme in the γ-family of pyridoxal-5’-phosphate (PLP)-dependent enzymes, catalyzes the α, γ-elimination of L-methionine and homocysteine. This enzyme exhibits anti...
T80273	M-TriDAP	N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid	NOD-like Receptor (NLR)
	M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) is a bioactive peptide functioning as a NOD1/2 agonist.		NOD-like Receptor (NLR)
T79189	1-Isopropyltryptophan	1-IsoPT	Indoleamine 2,3-Dioxygenase (IDO)
	1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].		Indoleamine 2,3-Dioxygenase (IDO)
T11359	Gamma-secretase modulator 2		Others
	Gamma-secretase modulator 2 is a potent, selective compound for the treatment of Alzheimer's disease, specifically designed to modulate γ-secretase activity. This modulation selectively attenuates the production of Aβ(1-...		Others
T38032	(R)-γ-Valerolactone
	(R)-γ-Valerolactone can be used in related research in the field of life sciences. Its product number is T38032 and CAS number is 58917-25-2.
T68738	(±)-γ-Tocopherol
	(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the syn...
T28542	Rivoglitazone HCl	CI-1037,CI1037,CS011,CS-011,CI 1037
	Rivoglitazone, also known as CI-1037; CS-011; DE-101; R-119702; Rivo, is a peroxisome proliferator-activated receptor γ agonist (PARPγ agonist) potentially for the treatment of type 2 diabetes. Rivoglitazone has been sho...
T12867L	SCH 50911		GABA Receptor
	SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor (IC50: 1.1 μM). SCH 50911 antagoni...		GABA Receptor
T26895	BRD0476	BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell ...
T81840	MBP (83-99)
	MBP (83-99) is an immunodominant epitope recognized by MBP-specific T cell lines, which stimulates both cell proliferation and IFN-γ secretion in T cells [1] [2].
T81120	SP4f		PPAR
	SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells. In Swiss albino mice, it diminishes blood glucose levels and lipid peroxidation while enhancing glutathione levels and catalase activity [1].		PPAR

Compounds

γ-2-MSH (41-58), amide

TP1532

Synonym:

Target:

2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol

Synonym: α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid

Target: GABA Receptor

Synonym: Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE

Target: P450, GABA Receptor

E 2012

T15184

Synonym:

Target: Gamma-secretase

Fluxametamide

T11307

Synonym:

Target: GABA Receptor

Emamectin Benzoate

T15212

Synonym: MK-244

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite

3-Nitrocoumarin

T10115

Synonym: 3-nitrochromen-2-one

Target: Phospholipase

GSK-4716

T5531

Synonym:

Target: Estrogen Receptor/ERR

Target: Gamma-secretase

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-

Synonym: Pargluva,BMS-298585

Target: PPAR

PI-103

T6143

Synonym: PI103,PI 103

Target: Apoptosis, DNA-PK, PI3K, mTOR, Autophagy

Avagacestat

T6249

Synonym: BMS-708163

Target: Gamma-secretase

S-(4-Hydroxybenzyl)glutathione

Target: Apoptosis, Others

2-(1,8-naphthyridin-2-yl)phenol

Synonym: Osugacestat,AL-101,BM-0018

Target: Gamma-secretase

Synonym: AVX754,SPD754

Target: HIV Protease, DNA/RNA Synthesis

4-Hydroxy-3-nitrophenylacetic acid

Synonym: JNJ 39659100,MBX 102

Target: PPAR

AMG131

T8780

Synonym: INT-131,AMG-131,CHS 131

Target: PPAR

Omipalisib

T1861

Synonym: GSK458,GSK2126458

Target: PI3K, mTOR, Autophagy

GSK1059615

T2357

Synonym: GSK 1059615,GSK-1059615

Target: Apoptosis, PI3K, mTOR

Synonym: N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251

γ-Glu-Cys (ammonium salt)

Synonym: MK0767,MK-0767

Synonym: γ-Glu-Ser TFA

Target: Calcium Channel

MitoEbselen-2 chloride

T33407

Synonym: MitoPeroxidase-2,MitoPeroxidase 2,MitoEbselen 2,MitoEbselen-2

Target:

L-Methionine γ-lyase

T79929

Synonym: Methionine lyase

Target:

M-TriDAP

T80273

Synonym: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid

Target: NOD-like Receptor (NLR)

1-Isopropyltryptophan

T79189

Synonym: 1-IsoPT

Target: Indoleamine 2,3-Dioxygenase (IDO)

gamma-secretase modulator 2

Synonym: CI-1037,CI1037,CS011,CS-011,CI 1037

Target: GABA Receptor

BRD0476

T26895

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

Cat No.	Product Name	Synonyms	Targets
T5581	6-(γ,γ-Dimethylallylamino)purine	N6-(2-lsopentenyl)adenine,Triacanthine	Others
	6-(γ,γ-Dimethylallylamino)purine (Triacanthine), which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic.		Others
T5320	Tulipalin A	α-methylene-γ-butyrolactone,2-Methylenebutyrolactone	Others , Drug Metabolite
	Tulipalin A (α-methylene-γ-butyrolactone) (2-Methylenebutyrolactone) which has some phytotoxicity is a natural compound extracted from Tulipa gesneriana.		Others , Drug Metabolite
TN1217	2'-O-Methylisoliquiritigenin		Dopamine Receptor , 5-HT Receptor , GABA Receptor
	2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a ...		Dopamine Receptor , 5-HT Receptor , GABA Receptor
T2S1464	Thiocolchicoside	Thiocolchicine 2-glucoside analog,Coltramyl	Others , GABA Receptor
	Thiocolchicoside (Thiocolchicine 2-glucoside analog) (Muscoril, Myoril, Neoflax) is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also glycine rece...		Others , GABA Receptor
T1633	β-Carotene	Carotaben,Beta-Carotene,Provitamin A	Apoptosis , ROS , Endogenous Metabolite
	β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene...		Apoptosis , ROS , Endogenous Metabolite
T5681	ETHYL CAFFEATE	ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB , COX , PGE Synthase , NO Synthase
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related s...		NF-κB , COX , PGE Synthase , NO Synthase
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
TN1132	Procyanidin A2		IL Receptor , TNF , transporter , Antibacterial
	Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell...		IL Receptor , TNF , transporter , Antibacterial
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
T4956	Tetrahydroxystilbene-2-O-β-D-glucoside	tetrahydroxyl diphenylethylene-2-o-gluco,EH-201	Others
	Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc...		Others
T37280	PE(18:1(9Z)/0:0)		Endogenous Metabolite
	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ...		Endogenous Metabolite
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
TCS0102	Pulegone	(+)-Pulegone	Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
	1. Pulegone ((+)-Pulegone) has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. 2. Pulegone induces a verapamil-sensitive psychostimulant effect t...		Calcium Channel , Endogenous Metabolite , TRP/TRPV Channel
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T3867	Alpinetin	(-)-alpinetin	BCL , PPAR
	Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he...		BCL , PPAR
T4839	Ac-Ala-OH	N-Acetylalanine,N-Acetyl-L-alanine	Others , Endogenous Metabolite
	Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro...		Others , Endogenous Metabolite
T35401	γ-Glu-Gly TFA
	γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid). It serves as an excitatory amino acid antagonist [1][2][3].
TN4860	Pueroside B		COX , PPAR
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece...		COX , PPAR
T14114	Acivicin	AT-125,U-42126	Others
	Acivicin (AT-125) is a γ-glutamyl transpeptidase (GGT) inhibitor derived from the Streptomyces sviceus natural product. It possesses anti-cancer and anti-parasitic properties and can effectively cross the blood-brain bar...		Others
T77207	Acivicin hydrochloride
	Acivicin hydrochloride (AT-125 hydrochloride), derived from Streptomyces sviceus, functions as a γ-glutamyl transpeptidase (GGT) inhibitor. This compound possesses the ability to cross the blood-brain barrier and demonst...
TN4959	Schizandriside		Prostaglandin Receptor
	Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. It shows significant cyt...		Prostaglandin Receptor
T35895	Ingenol 3,20-dibenzoate
	Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the partic...
TN3655	Cimiside E		ERK , TNF , ROS , Akt , PI3K , PKC , PPAR
	Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may b...		ERK , TNF , ROS , Akt , PI3K , PKC , PPAR

Natural Products

6-(γ,γ-Dimethylallylamino)purine

T5581

Synonym: N6-(2-lsopentenyl)adenine,Triacanthine

Target: Others

Tulipalin A

T5320

Synonym: α-methylene-γ-butyrolactone,2-Methylenebutyrolactone

Target: Others, Drug Metabolite

2'-O-Methylisoliquiritigenin

TN1217

Synonym:

Target: Dopamine Receptor, 5-HT Receptor, GABA Receptor

Thiocolchicoside

T2S1464

Synonym: Thiocolchicine 2-glucoside analog,Coltramyl

Target: Others, GABA Receptor

β-Carotene

T1633

Synonym: Carotaben,Beta-Carotene,Provitamin A

Target: Apoptosis, ROS, Endogenous Metabolite

ETHYL CAFFEATE

T5681

Synonym: ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

Target: IL Receptor, TNF, transporter, Antibacterial

Bardoxolone

T2915

Synonym: RTA 401,CDDO

Target: Others, Nrf2

Tetrahydroxystilbene-2-O-β-D-glucoside

T4956

Synonym: tetrahydroxyl diphenylethylene-2-o-gluco,EH-201

Target: Endogenous Metabolite

Ginsenoside F3

T3829

Synonym:

Target: Others, IFNAR, Interleukin

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Pulegone

TCS0102

Synonym: (+)-Pulegone

Target: Calcium Channel, Endogenous Metabolite, TRP/TRPV Channel

Jaceosidin

T3824

Synonym:

Target: Apoptosis, BCL, COX, UGT

Alpinetin

T3867

Synonym: (-)-alpinetin

Target: BCL, PPAR

Ac-Ala-OH

T4839

Synonym: N-Acetylalanine,N-Acetyl-L-alanine

Target: Others, Endogenous Metabolite

Synonym: AT-125,U-42126

Target: Others

Acivicin hydrochloride

Target: Prostaglandin Receptor

Ingenol 3,20-dibenzoate

Target: ERK, TNF, ROS, Akt, PI3K, PKC, PPAR

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02934	IL-2RG Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	IL-2RG Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.5 kDa and the accession number is Q68FU6.
TMPY-00857	IL-2RG Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293 Cells
	IL-2RG Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.3 kDa and the accession number is P34902.
TMPY-01853	SIRP gamma Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1.
TMPY-02646	NSE/ENO2 Protein, Human, Recombinant (His)	Human	E. coli
	The combination of silencing ENO2 and 2-deoxyglucose (2-DG) synergistically inhibited leukemia cell survival. ENO2 may be a biological marker for monitoring chemotherapeutic efficacy and relapse in ALL. Reduced ENO2 expr...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-02926	IL-2RG Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-2RG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.4 kDa and the accession number is P31785.
TMPY-01968	CD32A Protein, Human, Recombinant (167 His, His)	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-02949	AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)	Human	E. coli
	TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of imp...
TMPY-06511	IL-2RG Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	IL-2RG Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.10 kDa and the accession number is Q38JL2.
TMPY-02933	IL-2RG Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	IL-2RG Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55 kDa and the accession number is Q68FU6.
TMPY-06512	IL-2RG Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	IL-2RG Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.82 kDa and the accession number is Q38JL2.
TMPY-02122	IFNGR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea...
TMPY-01837	IL-2RG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-2RG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P34902.
TMPY-03756	BBOX1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last ste...
TMPY-06507	IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc)	Mouse	HEK293 Cells
	IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is NP_038591.1.
TMPY-02692	IgG2 Protein, Human, Recombinant (S257A)	Human	HEK293 Cells
	IgG2 Protein, Human, Recombinant (S257A) is expressed in HEK293 mammalian cells. The predicted molecular weight is 25 kDa and the accession number is P01859.
TMPJ-00239	IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)	Mouse	HEK293 Cells
	The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) pop...
TMPY-04422	Casein Kinase 1 gamma 2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Casein kinase I gamma 2 isoform (CSNK1G2), a member of the large casein kinase I (CKI) subfamily, protein kinase superfamily. It may affect the development of brain, and associate with vesicular trafficking and neurotran...
TMPY-04553	AKT3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	AKT3 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 81 kDa and the accession number is Q9Y243-1.
TMPJ-00960	TMPO Protein, Human, Recombinant (His)	Human	E. coli
	Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domai...
TMPK-00250	SIRP gamma Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma i...
TMPK-00251	SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma i...
TMPY-03753	WARS Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	WARS, also known as TrpRS, is an aminoacyl-tRNA synthetase that belongs to the class-I aminoacyl-tRNA synthetase family. There are two forms of tryptophanyl-tRNA synthetase: a cytoplasmic form, named WARS, and a mitochon...
TMPK-00238	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00986	IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00239	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00987	IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPJ-00900	TGM2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monom...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPK-00200	Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.5 kDa and the accession number is P31994-1.
TMPK-00199	Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16...
TMPJ-00248	SIRP gamma Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, ...
TMPJ-00192	CD32B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but dif...
TMPK-00211	Fc gamma RIIA/CD32a (H167) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Fc gamma RIIA/CD32a (H167) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 23.2 kDa and the accession number is P12318-1.
TMPK-00208	Fc gamma RIIA/CD32a (R167) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Fc gamma RIIA/CD32a (R167) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 23.2 kDa and the accession number is P12318-1.
TMPK-00210	Fc gamma RIIA/CD32a (R167) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Fc gamma RIIA/CD32a (R167) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 23.2 kDa and the accession number is P12318-1.
TMPK-00209	Fc gamma RIIA/CD32a (H167) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16...
TMPJ-00446	CD32A Protein, Human, Recombinant (R167, His)	Human	HEK293 Cells
	Receptors for the Fc region of IgG (FcγR) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Human FcγRs are divided into three classes designated FcγRI (CD64), FcγRII (C...
TMPY-00765	CD32B/Fcgr2b Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is P31994-2.
TMPJ-01234	IL-36 gamma Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in b...
TMPY-06359	IL-2RG Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-2RG Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 31.53 kDa and the accession number is NP_000197.1.
TMPY-05692	IL-2RG Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-2RG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.72 kDa and the accession number is P31785-1.
TMPY-00764	CD32A Protein, Human, Recombinant (167 Arg, His)	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 Arg, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-01983	CD32A Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.7 kDa and the accession number is P12318-1.
TMPY-01646	CD32A Protein, Human, Recombinant (167 Arg, hFc)	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 Arg, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.3 kDa and the accession number is AAA35827.1.
TMPY-01984	CD32A Protein, Human, Recombinant (167 Arg, His & Avi), Biotinylated	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 Arg, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.7 kDa and the accession number is P12318-1.
TMPJ-00711	GADD45G Protein, Human, Recombinant (His)	Human	E. coli
	Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPK-00459	Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
TMPK-00460	Fc gamma RIIIB/CD16b (NA2) Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate a...
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