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β-Carotene
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Catalog No. T1633Cas No. 7235-40-7
Alias Provitamin A, Carotaben, Beta-Carotene
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA.
β-Carotene
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Purity: 99.83%
Catalog No. T1633Alias Provitamin A, Carotaben, Beta-CaroteneCas No. 7235-40-7
β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mg | $34 | In Stock | In Stock | |
| 500 mg | $44 | In Stock | In Stock | |
| 1 g | $56 | In Stock | In Stock | |
| 5 g | $89 | - | In Stock | |
| 10 g | $113 | - | In Stock | |
| 25 g | $163 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $37 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.83%
Color:Transparent to Red
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Product Introduction
β-Carotene AI Summary
β-Carotene exhibits strong bioactivity as an inhibitor of TPA-induced Epstein-Barr Virus (EBV) early antigen activation in human Raji cells. It shows dose-dependent efficacy, with the highest inhibition of 100% observed at a 10 molar ratio relative to TPA. Additionally, the compound displays cytotoxicity against human Raji cells, with cell viability activity of 70% at a 1000 molar ratio. The IC50 for EBV-early antigen inhibition is determined to be 12.7 nM. β-Carotene also demonstrates beta-blocking activity with an activity level of 5.1 and shows toxicity after oral administration in mice, with LD50 values of 26.0 mg/kg and 6749.0 mg/kg at different test conditions. Furthermore, it has varied bioactivities against other biological targets, including antiviral actions against HCV and SARS-CoV-2, and inhibition of human HDAC6 enzyme, suggesting its potential applications in antiviral and anticancer therapies..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA. |
| Synonyms | Provitamin A, Carotaben, Beta-Carotene |
| Molecular Weight | 536.87 |
| Formula | C40H56 |
| Cas No. | 7235-40-7 |
| Smiles | C(=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=1C(C)(C)CCCC1C)\C)\C)/C)/C)\C=2C(C)(C)CCCC2C |
| Relative Density. | 0.941g/cm3 |
| Storage | keep away from direct sunlight,store under nitrogen,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 16.7 mg/mL (31.11 mM), Sonication is recommended.  Chloroform: 16.37 mg/mL (30.49 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Chloroform/DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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