Search Result

Search Results for " sap "

145

Compounds

142

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T35586	I-SAP
	I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtaine...
T1526	Nifuratel	NF 113,SAP 113,Methylmercadone	Antibacterial , Antibiotic , Parasite
	Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.		Antibacterial , Antibiotic , Parasite
T79779	SAP-04		STING
	SAP-04 is a potent, orally active STING agonist exhibiting significant immunomodulatory effects appropriate for cancer therapy [1].		STING
T7295	Miridesap	Ro63-8695,CPHPC,GSK2315698	Others
	Miridesap (GSK2315698) is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fluid and visceral amyloid de...		Others
T28043L	Minesapride		5-HT Receptor
	Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation.		5-HT Receptor
T68116L	(Rac)-Norcisapride		5-HT Receptor
	Norcisapride is a 5-hydroxytryptamine receptor 3 (5-HT3) and (5-hydroxytryptamine receptor 4 (5-HT4) dual agonist used for the treatment of gastrointestinal disorders, orofacial disorders, and otorhinolaryngologic disord...		5-HT Receptor
TP1970L	Prosaptide TX14(A) acetate	Prosaptide TX14(A) acetate(196391-82-9 free base)	ERK , GPR
	Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.		ERK , GPR
T6597	Mosapride Citrate	TAK-370 citrate,AS-4370 citrate,AS-4370	5-HT Receptor
	Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.		5-HT Receptor
TQ0245	Sapacitabine	CS682,CYC682	Nucleoside Antimetabolite/Analog
	Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.		Nucleoside Antimetabolite/Analog
T31675	Esaprazole	C/63	Others
	Esaprazole (C/63) has a dose - dependent cellular protective effect on the human gastric mucosa.		Others
T6092	Sapitinib	AZD-8931	EGFR
	Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the E...		EGFR
T1790	Fosaprepitant dimeglumine	L785298,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor
	Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...		Neurokinin receptor
T1838	Sapanisertib	TAK-228,MLN0128,INK 128	PI3K , mTOR , Autophagy
	Sapanisertib (INK 128) is an orally bioavailable inhibitor of raptor-mTOR (TOR complex 1 or TORC1) and rictor-mTOR (TOR complex 2 or TORC2) with potential antineoplastic activity.		PI3K , mTOR , Autophagy
T11894	Lusaperidone	R107474	Adrenergic Receptor
	Lusaperidone (R107474) is a potent α2-adrenergic receptor antagonist, a potential radioligand for the α (2)-adrenergic receptor, with inhibitory effects on α2A and α2C, with Ki values of 0.13 and 0.15 nM, respectively.		Adrenergic Receptor
T1291	Cisapride	Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel , 5-HT Receptor , HER
	Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease...		Potassium Channel , 5-HT Receptor , HER
T5386	Asapiprant		Prostaglandin Receptor
	Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki: 0.44 nM). It exhibited high affinity and selectivity for the DP1 receptor.		Prostaglandin Receptor
T8128	Mosapride	TAK-370,AS-4370	5-HT Receptor
	Mosapride (AS-4370) is a selective 5HT4 agonist		5-HT Receptor
T22871	Ipsapirone		5-HT Receptor
	Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses.		5-HT Receptor
T124683	Mi-Saponin B
	Mi-Saponin B is a useful organic compound for research related to life sciences. The catalog number is T124683 and the CAS number is 54328-43-7.
T126471	3'-Deoxy-4-O-methylepisappanol
	3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.
T125526	Herniariasaponin 7
	Herniariasaponin 7 is a useful organic compound for research related to life sciences. The catalog number is T125526 and the CAS number is 182625-43-0.
T126152	Saponin 2
	Saponin 2 is a useful organic compound for research related to life sciences. The catalog number is T126152 and the CAS number is 124853-92-5.
T26176	Saphenamycin	Racemic ssaphenamycin
	Saphenamycin is an antibiotic from a strain of Streptomyces.
T23189	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]		Others
	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.		Others
T126031	Gypsophilasaponin G1
	Gypsophilasaponin G1 is a useful organic compound for research related to life sciences. The catalog number is T126031 and the CAS number is 133632-77-6.
T81217	SAP6
	SAP6 is a bioactive peptide that inhibits virus entry into cells.
T81387	Prosaptide Tx14(A) TFA
	Prosaptide Tx14(A) TFA is a prosaposin-derived peptide and a potent agonist of both GPR37L1 and GPR37, exhibiting EC50 values of 5 nM and 7 nM, respectively. In Schwann cells, this compound enhances phosphorylation of bo...
TP2256	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]		Others
	Heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens] is a peptide with the sequence H2N-Phe-Thr-Val-Asp-Arg- Pro-Phe-Leu-Phe-Leu-Ile-Tyr-Glu-His-Arg-OH, MW=1953.25.		Others
TP2188	Type I hair keratin fragment [Homo sapiens]/[Ovis aries]/[Rattus norvegicus]		Others
	The human type I hair keratin subfamily comprises nine individual members, which can be subdivided into three groups. Group A (hHa1, hHa3-I, hHa3-II, hHa4) and B (hHa7, hHa8) each contains structurally related hair kerat...		Others
TP2190	Vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]		Others
	Vitamin D-binding protein is a multifunctional, highly expressed, polymorphic serum protein. These range from the transport of vitamin D metabolites to possible roles in the immune system and host defense. The molecular ...		Others
TP2176	Amyloid A protein fragment [Homo sapiens]		Others
	Amyloid A proteins (H2N-Ala-Gly-Leu-Pro-Glu-Lys-Tyr-OH) are a family of apolipoproteins associated with high-density lipoprotein in plasma. Different isoforms of SAA are expressed constitutively at different levels or in...		Others
TP2259	Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]		Others
	Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition m...		Others
T37382	1,2,3-Trieicosapentaenoyl-rac-glycerol
	1,2,3-Trieicosapentaenoyl-rac-glycerol (EPA-TG) is a glycerol ester of eicosapentaenoic acid , which is an ω-3 fatty acid. An EPA-TG emulsion, administered i.v., lowers leukotriene B4 production by 40% in polymorphonucle...
T36426	Eicosapentaenoyl 1-propanol-2-amide
	Monoacylglycerols (MAGs) of ω-3 polyunsaturated fatty acids have diverse physiological and health effects. In particular, MAGs containing docosahexaenoic acid or eicosapentaenoic acid have anti-proliferative properties a...
T38208	Heneicosapentaenoic Acid
	Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA) except elongated with one...
T27623	Ipsapirone hydrochloride	BAY q 7821,BAY q-7821,BAY q7821,Ipsapirone HCl
	Ipsapirone, a pyrimidinylpiperazine ligand, is potent and specific for 5-HT1A receptors and has potential therapeutic use in affective disorders.
T68654	Sapintoxin D
	Sapintoxin D is a fluorescent phorbol ester and selective activator of protein kinase C.
T125328	Yayoisaponin B
	Yayoisaponin B is a useful organic compound for research related to life sciences. The catalog number is T125328 and the CAS number is 218934-74-8.
T125858	Priverosaponin B 22-acetate
	Priverosaponin B 22-acetate is a useful organic compound for research related to life sciences. The catalog number is T125858 and the CAS number is 144379-37-3.
T28785	Sisapronil	PF-0241851,PF 0241851,PF0241851
	Sisapronil is a member of the phenylpyrazole class of antiparasitics.
T70070	Cisapride tartrate
	Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisa...
T28411	Physapubenolide	NSC 368674,NSC368674,NSC-368674
	Physapubenolide is natural cytotoxic withanolide antitumor agent. Physapubenolide induces apoptosis by decreasing mitochondrial membrane potential and elevating the Bax/Bcl-2 protein expression ratio.
T126349	Cynarasaponin H
	Cynarasaponin H is a useful organic compound for research related to life sciences. The catalog number is T126349 and the CAS number is 114006-82-5.
T126228	Asperosaponin V
	Asperosaponin V is a useful organic compound for research related to life sciences. The catalog number is T126228 and the CAS number is 120481-38-1.
T22856	IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]		Others
	IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early...		Others
T70806	Metformin icosapent
	Metformin icosapent is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose.
T34516	Sapelin B	NSC 270047,NSC270047,NSC-270047
	Sapelin B is a triterpenoid.
T125651	Matesaponin 2
	Matesaponin 2 is a useful organic compound for research related to life sciences. The catalog number is T125651 and the CAS number is 164178-27-2.
T128908	Abrisaponin D1
	Abrisaponin D1 is a useful organic compound for research related to life sciences and the catalog number is T128908.
T34511	Sandosaponin B
	Sandosaponin B is a olean-12-ene-type triterpene oligoglycoside isolated from kidney bean, the seed of Phaseolus vulgaris L.

Compounds

Synonym: NF 113,SAP 113,Methylmercadone

Target: Antibacterial, Antibiotic, Parasite

Synonym: Ro63-8695,CPHPC,GSK2315698

Target: 5-HT Receptor

(Rac)-Norcisapride

T68116L

Synonym:

Target: 5-HT Receptor

Prosaptide TX14(A) acetate

TP1970L

Synonym: Prosaptide TX14(A) acetate(196391-82-9 free base)

Target: ERK, GPR

Mosapride Citrate

T6597

Synonym: TAK-370 citrate,AS-4370 citrate,AS-4370

Target: 5-HT Receptor

Sapacitabine

TQ0245

Synonym: CS682,CYC682

Target: Nucleoside Antimetabolite/Analog

Fosaprepitant dimeglumine

T1790

Synonym: L785298,MK-0517,Fosaprepitant dimeglumine salt

Target: Neurokinin receptor

Sapanisertib

T1838

Synonym: TAK-228,MLN0128,INK 128

Target: PI3K, mTOR, Autophagy

Lusaperidone

T11894

Synonym: R107474

Target: Adrenergic Receptor

Cisapride

T1291

Synonym: Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase

Target: Potassium Channel, 5-HT Receptor, HER

Asapiprant

T5386

Synonym:

Target: Prostaglandin Receptor

Mosapride

T8128

Synonym: TAK-370,AS-4370

Target: 5-HT Receptor

Ipsapirone

T22871

Synonym:

Target: 5-HT Receptor

3'-Deoxy-4-O-methylepisappanol

Synonym: Racemic ssaphenamycin

Target:

prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

Prosaptide Tx14(A) TFA

T81387

Synonym:

Target:

heparin cofactor II precursor (SERPIND1) fragment [Homo sapiens]

TP2256

Synonym:

Target: Others

type I hair keratin fragment [Homo sapiens]/[Ovis aries]/[Rattus norvegicus]

TP2188

Synonym:

Target: Others

vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]

TP2190

Synonym:

Target: Others

amyloid A protein fragment [Homo sapiens]

TP2176

Synonym:

Target: Others

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

TP2259

Synonym:

Target: Others

1,2,3-Trieicosapentaenoyl-rac-glycerol

T37382

Synonym:

Target:

Eicosapentaenoyl 1-propanol-2-amide

T36426

Synonym:

Target:

Heneicosapentaenoic Acid

T38208

Synonym:

Target:

Ipsapirone hydrochloride

T27623

Synonym: BAY q 7821,BAY q-7821,BAY q7821,Ipsapirone HCl

Priverosaponin B 22-acetate

Synonym: PF-0241851,PF 0241851,PF0241851

Synonym: NSC 368674,NSC368674,NSC-368674

IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

Synonym: NSC 270047,NSC270047,NSC-270047

Cat No.	Product Name	Synonyms	Targets
TN1383	Timosaponin B III	Anemarsaponin BIII	Others , Platelet aggregation
	Timosaponin B III (Anemarsaponin BIII) is a bioactive steroidal saponin isolated from Anemarrhena asphodeloides Bge. Timosaponin B III possesses anti-inflammatory, anti-platelet aggregative and anti-depressive effects.		Others , Platelet aggregation
T75675	Nepasaikosaponin K		Antiviral
	Nepasaikosaponin K is a small molecule compound isolated from Chaikosaponin root with anti-influenza and antiviral activity and can be used in the study of viral infections.		Antiviral
T8209	Saikosaponin b3		Others
	Saikosaponin b3 is isolated from the roots of Bupleurum falcatum L.. Saikosaponin b3 inhibits ACTH-induced lipolysis in the fat cells and exhibits analgesic effects.		Others
TMA1570	Sappanone A		NF-κB , Nrf2
	Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.		NF-κB , Nrf2
TN1866	Licoricesaponin G2
	Licoricesaponin G2 is a pentacyclic triterpenoid derived from Glycyrrhiza aspera, which can be used to differentiate crude liquorice from honey-processed liquorice.
TN2230	Soyasaponin Ba		Others
	Soyasaponin Ba may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without ...		Others
T2S2295	Timosaponin A1		Others
	Timosaponin A1 is a coprostane type steroidal saponin found in Rhizoma Anemarrhenae.		Others
T4085	Paris saponin VII	Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
	Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T3909	Pulsatilla saponin D	Hederacolchiside A,SB365	Apoptosis , Others
	Pulsatilla saponin D (Hederacolchiside A) has exhibited potential beneficial effects as a chemopreventive agent for critical health conditions including cancer, and it inhibits cell growth via cell cycle arrest and apopt...		Apoptosis , Others
TN1600	Eclalbasaponin I		Others
	Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...		Others
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
T2768	Saikosaponin A		NF-κB , Antibacterial , Liver X Receptor
	Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...		NF-κB , Antibacterial , Liver X Receptor
T3912	Saikosaponin B1		Others
	Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.		Others
T3913	Saikosaponin D		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
	Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
TN2289	Licorice-saponin H2	Licoricesaponin H2	Others
	Licorice-saponin H2 (Licoricesaponin H2) is a natural product		Others
TN2119	Pulsatilla saponin H		Others
	Pulsatilla saponin H is a natural product isolated from the Roots of Pulsatilla koreana.		Others
TN2443	Chikusetsusaponin Ib	Chikusetsu saponin Ib	AChE
	Chikusetsusaponin Ib (Chikusetsu saponin Ib) is an inhibitor of AChE and can be used in studies about anti-Alzheimer's diseases.		AChE
T5368	Eicosapentaenoic Acid		Histone Demethylase , Others , Endogenous Metabolite
	Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.		Histone Demethylase , Others , Endogenous Metabolite
T3S0601	Buddlejasaponin IVb	Saikosaponin 1b	Others
	1. Buddlejasaponin IVb (Saikosaponin 1b)(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.		Others
T8210	Saikosaponin B4		Others
	Saikosaponin B4 is isolated from the MeOH extract of the roots of Bupleurum falcatum L.		Others
TN2232	Soyasaponin Ab		NOS , NF-κB , COX
	Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.		NOS , NF-κB , COX
TN1014	Saikosaponin E		Others
	Saikosaponin E is a natural product isolated from the herbs of Bupleurum.		Others
T6S1780	Protosappanin B	Q-100961,FT-0689654	Apoptosis
	1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi...		Apoptosis
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
TN1140	Onjisaponin B		AMPK , mTOR , Autophagy
	Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α±-synuclein, it may have potential therapeutic effects on Parki...		AMPK , mTOR , Autophagy
TJS0502	Ilexsaponin B2
	Ilexsaponin B2 is a natural product for research related to life sciences. The catalog number is TJS0502 and the CAS number is 108906-69-0.
T2S0690	Ecliptasaponin A	Echinocystic acid-3-o-glucoside	Others
	1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-...		Others
TN6931	Anemarrhenasaponin Ia	(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan	Others
	Anemarrhenasaponin Ia ((2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]...		Others
TN7243	Fallaxsaponin A
	Fallaxsaponin A is isolated from the alkaline hydrolysis products of total saponins in Radix Palygalae.
TN1539	Cussosaponin C		Others
	Cussosaponin C is a natural product isolated from Pulsatilla koreana Nakai.		Others
T4S0675	Polygalasaponin V		Others
	Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk m...		Others
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T2698	Asperosaponin VI	Akebia saponin D,Asperosaponin Ⅵ	Apoptosis , Others , Caspase
	Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.		Apoptosis , Others , Caspase
TN2329	Zingiberen newsaponin	Zingiberensis saponin I	PARP , PAFR , Caspase
	Zingiberen newsaponin is a steroidal saponin from Dioscorea zingiberensis.		PARP , PAFR , Caspase
T3395	Timosaponin AIII	Filiferin B,AneMarsaponin A3,Timosaponin A3	AChE , mTOR
	Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...		AChE , mTOR
T3345	Hederasaponin B	Eleutheroside M,Hederacoside B	Others , Virus Protease
	Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.		Others , Virus Protease
T7117	Sapropterin dihydrochloride	Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride	Hydroxylase
	Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.		Hydroxylase
T2733	Sarsasapogenin	Parigenin,Sarsagenin	Apoptosis , NF-κB , Endogenous Metabolite
	Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o...		Apoptosis , NF-κB , Endogenous Metabolite
T7068	Eicosapentaenoic acid ethyl ester	Icosapent ethyl,EPA ethyl ester,Ethyl eicosapentaenoate	Others , Endogenous Metabolite
	Eicosapentaenoic acid ethyl ester (Ethyl eicosapentaenoate) is an omega-3 fatty acid.		Others , Endogenous Metabolite
T3S0687	Ecliptasaponin D		Others
	Ecliptasaponin D is a natural product for research related to life sciences. The catalog number is T3S0687 and the CAS number is 206756-04-9.		Others
T19295	Docosapentaenoic acid 22n-3		Endogenous Metabolite
	Docosapentaenoic acid 22n-3 is present in the cell membranes of all animals and is a component of phospholipids.		Endogenous Metabolite
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T7030	Anemarsaponin B		p38 MAPK , NF-κB , MEK , COX , NO Synthase
	Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B c...		p38 MAPK , NF-κB , MEK , COX , NO Synthase
TN2225	Soyasapogenol B		Apoptosis , Autophagy
	Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.		Apoptosis , Autophagy
T4955	saponaretin	Isovitexin,Apigenin-6-C-glucoside	Apoptosis , Antioxidant
	saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on.		Apoptosis , Antioxidant
T3394	Timosaponin BII	Prototimosaponin A III	Beta Amyloid , Others , BACE
	Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...		Beta Amyloid , Others , BACE
T3863	Chikusetsusaponin IVa	Calenduloside F	AMPK
	Chikusetsusaponin IVa (Calenduloside F) is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used...		AMPK
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T13589	Caesappanin C		Others
	Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.		Others
T6654	Saponins	Sapogenins Glycosides,Saponin	Others
	Saponins (Sapogenins Glycosides) are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effecti...		Others
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Natural Products

Timosaponin B III

TN1383

Synonym: Anemarsaponin BIII

Target: Others, Platelet aggregation

Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Pulsatilla saponin D

T3909

Synonym: Hederacolchiside A,SB365

Target: Apoptosis, Others

Synonym: Progenin III

Target: Apoptosis, Others

Saikosaponin A

T2768

Synonym:

Target: NF-κB, Antibacterial, Liver X Receptor

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Licorice-saponin H2

TN2289

Synonym: Licoricesaponin H2

Target: Others

Pulsatilla saponin H

Synonym: Chikusetsu saponin Ib

Target: AChE

Eicosapentaenoic Acid

T5368

Synonym:

Target: Histone Demethylase, Others, Endogenous Metabolite

Buddlejasaponin IVb

T3S0601

Synonym: Saikosaponin 1b

Target: NOS, NF-κB, COX

Synonym: Q-100961,FT-0689654

Target: Beta Amyloid, Caspase

Onjisaponin B

TN1140

Synonym:

Target: AMPK, mTOR, Autophagy

Synonym: Echinocystic acid-3-o-glucoside

Target: Others

Anemarrhenasaponin Ia

TN6931

Synonym: (2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan

Liriope muscari baily saponins C

Synonym: Akebia saponin D,Asperosaponin Ⅵ

Target: Apoptosis, Others, Caspase

Zingiberen newsaponin

TN2329

Synonym: Zingiberensis saponin I

Target: PARP, PAFR, Caspase

Timosaponin AIII

T3395

Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3

Target: AChE, mTOR

Hederasaponin B

T3345

Synonym: Eleutheroside M,Hederacoside B

Target: Others, Virus Protease

Sapropterin dihydrochloride

T7117

Synonym: Sapropterin Hydrochloride,6R-Tetrahydro-L-biopterin dihydrochloride,6R-BH4 dihydrochloride

Target: Hydroxylase

Sarsasapogenin

T2733

Synonym: Parigenin,Sarsagenin

Target: Apoptosis, NF-κB, Endogenous Metabolite

Eicosapentaenoic acid ethyl ester

T7068

Synonym: Icosapent ethyl,EPA ethyl ester,Ethyl eicosapentaenoate

Target: Others, Endogenous Metabolite

Docosapentaenoic acid 22n-3

T19295

Synonym:

Target: Endogenous Metabolite

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

anemarsaponin B

T7030

Synonym:

Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase

Soyasapogenol B

TN2225

Synonym:

Target: Apoptosis, Autophagy

saponaretin

T4955

Synonym: Isovitexin,Apigenin-6-C-glucoside

Target: Apoptosis, Antioxidant

Timosaponin BII

T3394

Synonym: Prototimosaponin A III

Target: Beta Amyloid, Others, BACE

Chikusetsusaponin IVa

T3863

Synonym: Calenduloside F

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Synonym: Sapogenins Glycosides,Saponin

Target: Others

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00765	Pentraxin 2/SAP Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ...
TMPY-02440	SAP/SH2D1A Protein, Human, Recombinant (His)	Human	E. coli
	SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPK-00113	Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ...
TMPY-03195	Serum Amyloid P Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743.
TMPY-00666	Serum Amyloid P Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serum Amyloid P Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P12246.
TMPY-02765	GM2A Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	GM2A (GM2 ganglioside activator), is a lipid transfer protein which belongs to the ML domain family. GM2A can accommodate several single chain phospholipids and fatty acids. It also exhibits some calcium-independent phos...
TMPY-06808	Serum Amyloid P Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric ac...
TMPJ-00652	PSD-95 Protein, Rat, Recombinant (His)	Rat	E. coli
	Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain，3 PDZ (DHR) domains and 1 SH3 dom...
TMPY-04510	PSAP/Prosaposin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previ...
TMPJ-00667	DEFB4A Protein, Human, Recombinant	Human	E. coli
	β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of t...
TMPY-00209	PSAP/Prosaposin Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Prosaposin (PSAP) gene mutations, affecting saposin B (Sap-B) domain, cause a rare metachromatic leukodystrophy (MLD) variant in which arylsulfatase A (ARSA) activity is normal. The human prosaposin gene (PSAP) was previ...
TMPY-00098	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the acces...
TMPY-06206	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His)	HMPV	HEK293 Cells
	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is...
TMPJ-01179	SWSAP1 Protein, Human, Recombinant (His)	Human	E. coli
	SWSAP1 is a nucleus ATPase protein, interacts with ZSWIM7 and forms a functional complex. The complexs involved in homologous recombination repair and stabilizes each other. SWS1AP1 also interacts with RAD51, RAD51B, RAD...
TMPY-00292	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight...
TMPY-00064	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.1 kDa and the ...
TMPY-00240	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the access...
TMPY-00071	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 k...
TMPY-00255	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.4 kDa and the accessio...
TMPY-00245	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the ...
TMPY-06207	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His)	HMPV	HEK293 Cells
	Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is...
TMPY-00041	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.3 kDa and the acce...
TMPY-00102	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the acc...
TMPH-03125	Saposin-B-Val Protein, Pig, Recombinant (Flag & His)	Sus scrofa (Pig)	P. pastoris (Yeast)
	Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). S...
TMPY-00312	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.6 kDa and the acc...
TMPY-00284	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight i...
TMPY-00219	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession numbe...
TMPH-00714	SapA Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. SapA Protein, E. coli, ...
TMPH-02709	SAP130 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. SAP130 Protei...
TMPY-00307	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the a...
TMPY-00043	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the acces...
TMPJ-00218	SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like ...
TMPY-01831	SLAMF8 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a...
TMPK-01174	SLAMF6 Protein, Mouse, Recombinant (aa 31-239, His)	Mouse	HEK293 Cells
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
TMPK-00651	SLAMF6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
TMPK-00222	SLAMF6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	SLAMF6 (signaling lymphocyte activation molecule 6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules. It is known to be wide...
TMPY-01816	Pentraxin 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom...
TMPY-02582	Ferritin light chain Protein, Human, Recombinant (His)	Human	E. coli
	Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light...
TMPJ-00455	SLAMF5 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD84, also called SLAMF5, is a member of the CD2 subgroup of the immunoglobulin receptor superfamily. Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based ...