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Prosaptide TX14(A) acetate

Catalog No. TP1970L CAS TP1970L

Synonyms: Prosaptide TX14(A) acetate(196391-82-9 free base)

Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.

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Prosaptide TX14(A) acetate Chemical Structure

Prosaptide TX14(A) acetate, CAS TP1970L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 148.00
5 mg	In stock	$ 365.00
10 mg	In stock	$ 545.00
25 mg	In stock	$ 878.00
50 mg	In stock	$ 1,190.00
100 mg	In stock	$ 1,630.00

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Purity: 95.29%

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Description	Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.
Targets&IC50	GPR37:7 nM(EC50), GPR37L1:5 nM(EC50)
In vitro	Prosaptide Tx14(A) is a potent GPR37L1(EC50: 5 nM) and GPR37(EC50: 7 nM) agonist, bound to both receptors and activated signaling in a GPR37- and GPR37L1-dependent manner[1].

Synonyms	Prosaptide TX14(A) acetate(196391-82-9 free base)
Molecular Weight	1639.76
Formula	C71H114N16O28
CAS No.	TP1970L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Meyer RC, et al. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A. 2013;110(23):9529-9534. 2. Campana WM, et al. Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells. FASEB J. 1998;12(3):307-314.

Related compound libraries

This product is contained In the following compound libraries：

Reprogramming Compound Library Anti-Pancreatic Cancer Compound Library HIF-1 Signaling Pathway Compound Library Anti-Obesity Compound Library Anti-Liver Cancer Compound Library Anti-Prostate Cancer Compound Library Peptide Compound Library Endocrinology-Hormone Compound Library Anti-Colorectal Cancer Compound Library

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Keywords

Prosaptide TX14(A) acetate TP1970L Endocrinology/Hormones GPCR/G Protein MAPK ERK GPR Prosaptide TX14(A) acetate(196391-82-9 free base) Prosaptide TX-14(A) acetate Prosaptide TX14(A) Acetate inhibitor inhibit

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