Search Result

Search Results for " vegfr-3 "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T72924	VEGFR-3-IN-1		VEGFR
	VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...		VEGFR
T2032	WHI-P180	Janex 3	EGFR , VEGFR , c-RET , CDK
	WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.		EGFR , VEGFR , c-RET , CDK
T63112	VEGFR-IN-3
	VEGFR-IN-3 (compound 3f), a VEGFR inhibitor, exhibits potent anticancer activity by inhibiting the growth of OVCAR-4 and MDA-MB-468 cancer cells with IC50 values of 0.29 and 0.35 μM, respectively. It has potential applic...
T4425	JK-P3		VEGFR
	JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...		VEGFR
T9473	4SC-203		FLT
	4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...		FLT
T22432	SU5208	3-[(Thien-2-yl)methylene]-2-indolinone	VEGFR
	SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).		VEGFR
T79588	HCA/VEGFR-2-IN-3		VEGFR
	hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. This compound inhibits VEGFR-2 with an IC50 of 358 nM and exhibits high a...		VEGFR
T22431	SU5204	3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one	EGFR , VEGFR , HER
	SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)		EGFR , VEGFR , HER
T2638	Gandotinib	LY2784544	VEGFR , FGFR , FLT , JAK
	LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.		VEGFR , FGFR , FLT , JAK
T79858	TIE-2/VEGFR-2 kinase-IN-3
	TIE-2/VEGFR-2 kinase-IN-3, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting IC50 values of 6.9 nM and 3.5 nM, respectively. This compound is useful f...
T0093L	Sorafenib	Bay 43-9006	Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
	Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity...
T1836	AZD2932		VEGFR , FLT , PDGFR , c-Kit
	AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.		VEGFR , FLT , PDGFR , c-Kit
T2054	Altiratinib	DCC-2701	VEGFR , Tie-2 , FLT , Trk receptor , c-Met/HGFR
	Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist...		VEGFR , Tie-2 , FLT , Trk receptor , c-Met/HGFR
T2358	ENMD-2076		Apoptosis , VEGFR , FGFR , FLT , c-RET , PDGFR , Src , Aurora Kinase
	ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.
T8482	Ripretinib	DCC-2618	Apoptosis , VEGFR , FLT , PDGFR , c-Kit
	Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.		Apoptosis , VEGFR , FLT , PDGFR , c-Kit
T0093	Sorafenib tosylate	Bay 43-9006	Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
	Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).
T4053	AST 487	NVP-AST 487	VEGFR , FLT , c-RET , Bcr-Abl , c-Kit
	AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.		VEGFR , FLT , c-RET , Bcr-Abl , c-Kit
T7493	AG-13958	AG-013958	VEGFR
	AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.		VEGFR
T2586	Cabozantinib	XL184,BMS-907351	Apoptosis , VEGFR , FLT , c-Met/HGFR , c-RET , TAM Receptor , c-Kit
	Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity...
T4349	Sitravatinib	MG516,MGCD516	Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
	Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T6479	Dovitinib lactate hydrate	Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) R...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T2514	Linifanib	ABT-869,RG3635,AL-39324	Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
	Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T6289	Dovitinib	TKI258,CHIR-258	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...		VEGFR , FGFR , FLT , PDGFR , c-Kit
T7104	Dovitinib lactate	CHIR-258 lactate,TKI-258 lactate	VEGFR , FGFR , FLT , PDGFR , c-Kit
	Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).		VEGFR , FGFR , FLT , PDGFR , c-Kit
T5164	Cabozantinib hydrochloride	XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351	VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
	Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6 nM).		VEGFR , FLT , c-Met/HGFR , TAM Receptor , c-Kit , ROR
T6028	PF 477736	PF 00477736,PF-477736,PF-736,PF-00477736,PF477736	c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
	PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T3691	(Rac)-SAR131675	SAR131675	VEGFR
	(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is h...		VEGFR
T63505	Tivozanib hydrochloride hydrate
	Tivozanib hydrochloride hydrate is a selective, potent, orally active VEGFR tyrosine kinase inhibitor that acts on VEGFR-1 (IC50: 0.21 nM), VEGFR-2 (IC50: 0.16 nM), and VEGFR-3 (IC50: 0.24 nM). Tivozanib hydrochloride hy...
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T11153	EG00229		Others
	EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A t...		Others
T6036	Brivanib	BMS-540215	EGFR , VEGFR , FGFR , Autophagy
	Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.		EGFR , VEGFR , FGFR , Autophagy
T3463	NVP-ACC789	ACC-789,ZK202650	VEGFR , PDGFR
	ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.		VEGFR , PDGFR
T16909	Sorafenib-d3	Sorafenib (D3),Bay 43-9006 (D3)	Raf , VEGFR
	Sorafenib-d3 (Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively).		Raf , VEGFR
T0263	Chloropyramine hydrochloride	Nilfan,Alergosan,Halopyramine hydrochloride	FAK , VEGFR , Histamine Receptor
	Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.		FAK , VEGFR , Histamine Receptor
T2500	Cediranib	AZD2171,NSC-732208	VEGFR , FLT , PDGFR , c-Kit , Autophagy
	Cediranib (AZD2171) (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro, also inhibits Flt1/4 (IC50: 5 nM/≤3 nM), similar activity against PDGFRβ and c-Kit...		VEGFR , FLT , PDGFR , c-Kit , Autophagy
T14943	CGP60474		VEGFR , CDK , PKC
	CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.		VEGFR , CDK , PKC
T2288	Motesanib	AMG 706	VEGFR , c-Kit
	Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-deriv...		VEGFR , c-Kit
T0097L	Pazopanib	GW786034	VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...		VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T2456	Tivozanib	AV-951,KRN951	VEGFR , PDGFR , Ephrin Receptor
	Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.		VEGFR , PDGFR , Ephrin Receptor
T2624	OSI-930	OSI 930	Apoptosis , c-Fms , Raf , VEGFR , FLT , CSF-1R , Src , c-Kit
	OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.
T2656	Fruquintinib	HMPL-013	VEGFR
	Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.		VEGFR
T1656L	Vandetanib Fumarate	HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib
	Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epider...
T77148	Pegdinetanib
	Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for h...
T79495	VEGFR-2-IN-32		VEGFR
	VEGFR-2-IN-32 (Comp 3a) is an inhibitor of VEGFR-2, exhibiting an inhibitory concentration (IC 50) of 8.93 nM, and demonstrates cytotoxic activity towards PC-3 cells with an IC 50 of 1.22 μM, indicating its potential uti...		VEGFR
T63870	Multi-kinase-IN-3
	Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).
T12791	(S)-3-Hydroxy Midostaurin	(S)-CGP52421	Others
	(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).		Others
T74127	N-Desethyl Sunitinib hydrochloride
	N-Desethyl Sunitinib (SU-12662) (hydrochloride), a metabolite of sunitinib, is a robust ATP-competitive inhibitor of VEGFR, PDGFRβ, and KIT, demonstrating inhibition constants (K i values) of 2, 9, 17, 8, and 4 nM for VE...
T12145	N-Desethyl Sunitinib	SU-11662	VEGFR , PDGFR , c-Kit
	N-Desethyl Sunitinib (SU-11662) is a sunitinib metabolite.		VEGFR , PDGFR , c-Kit
T71576	SIM010603
	SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived g...
T12976	Sorafenib-d4	Sorafenib (D4),Bay 43-9006 (D4)	Others
	Sorafenib D4 is the deuterium labeled Sorafenib. Sorafenib is an inhibitor of multikinase (Raf-1, B-Raf, and VEGFR-3 IC50s of 6 nM, 20 nM, and 22 nM, respectively).		Others

Compounds

Target: EGFR, VEGFR, c-RET, CDK

Synonym: 3-[(Thien-2-yl)methylene]-2-indolinone

Synonym: 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one

Target: EGFR, VEGFR, HER

Gandotinib

T2638

Synonym: LY2784544

Target: VEGFR, FGFR, FLT, JAK

TIE-2/VEGFR-2 kinase-IN-3

Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy

AZD2932

T1836

Synonym:

Target: VEGFR, FLT, PDGFR, c-Kit

Altiratinib

T2054

Synonym: DCC-2701

Target: VEGFR, Tie-2, FLT, Trk receptor, c-Met/HGFR

ENMD-2076

T2358

Synonym:

Target: Apoptosis, VEGFR, FGFR, FLT, c-RET, PDGFR, Src, Aurora Kinase

Ripretinib

T8482

Synonym: DCC-2618

Target: Apoptosis, VEGFR, FLT, PDGFR, c-Kit

Sorafenib tosylate

T0093

Synonym: Bay 43-9006

Target: Apoptosis, Raf, VEGFR, FLT, Ferroptosis, PDGFR, c-Kit, Autophagy

AST 487

T4053

Synonym: NVP-AST 487

Target: VEGFR, FLT, c-RET, Bcr-Abl, c-Kit

Synonym: XL184,BMS-907351

Target: Apoptosis, VEGFR, FLT, c-Met/HGFR, c-RET, TAM Receptor, c-Kit

Sitravatinib

T4349

Synonym: MG516,MGCD516

Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor

Dovitinib lactate hydrate

T6479

Synonym: Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Linifanib

T2514

Synonym: ABT-869,RG3635,AL-39324

Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy

Dovitinib

T6289

Synonym: TKI258,CHIR-258

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Dovitinib lactate

T7104

Synonym: CHIR-258 lactate,TKI-258 lactate

Target: VEGFR, FGFR, FLT, PDGFR, c-Kit

Cabozantinib hydrochloride

T5164

Synonym: XL184,Cabozantinib hydrochloride (849217-68-1(free base)),BMS-907351

Target: VEGFR, FLT, c-Met/HGFR, TAM Receptor, c-Kit, ROR

PF 477736

T6028

Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736

Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase

Tivozanib hydrochloride hydrate

Target: Apoptosis, VEGFR

Target: EGFR, VEGFR, FGFR, Autophagy

NVP-ACC789

T3463

Synonym: ACC-789,ZK202650

Target: VEGFR, PDGFR

Sorafenib-d3

T16909

Synonym: Sorafenib (D3),Bay 43-9006 (D3)

Target: Raf, VEGFR

Chloropyramine hydrochloride

T0263

Synonym: Nilfan,Alergosan,Halopyramine hydrochloride

Target: FAK, VEGFR, Histamine Receptor

Cediranib

T2500

Synonym: AZD2171,NSC-732208

Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy

CGP60474

T14943

Synonym:

Target: VEGFR, CDK, PKC

Motesanib

T2288

Synonym: AMG 706

Target: VEGFR, c-Kit

Pazopanib

T0097L

Synonym: GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Tivozanib

T2456

Synonym: AV-951,KRN951

Target: VEGFR, PDGFR, Ephrin Receptor

OSI-930

T2624

Synonym: OSI 930

Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit

Synonym: HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib

(S)-3-Hydroxy Midostaurin

T12791

Synonym: (S)-CGP52421

Target: Others

N-Desethyl Sunitinib hydrochloride

Target: VEGFR, PDGFR, c-Kit

Synonym: Sorafenib (D4),Bay 43-9006 (D4)

Target: Others

Cat No.	Product Name	Synonyms	Targets
TN2019	Orobol	3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon	BCL , Caspase , PI3K
	Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...		BCL , Caspase , PI3K
T13108	Pamufetinib	H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115	VEGFR , c-Met/HGFR
	Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase(IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively).		VEGFR , c-Met/HGFR
T1152	Albendazole	SKF-62979	HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
	Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.

Natural Products

Orobol

TN2019

Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon

Target: BCL, Caspase, PI3K

Pamufetinib

T13108

Synonym: H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115

Target: VEGFR, c-Met/HGFR

Albendazole

T1152

Synonym: SKF-62979

Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-00949	VEGFR3/FLT4 Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPK-00446	VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPY-01937	VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPK-00445	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly ...
TMPY-06620	VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-01069	VEGFR3/FLT4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-03156	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01007	VEGFC Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-03155	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-03150	VEGFD Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-03200	VEGFD Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-02589	VEGFD Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His)	Human	HEK293
	NTM (Neurotrimin) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylph...
TMPY-06986	FGF-8b Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00132	Mesothelin Protein, Human, Recombinant	Human	HEK293
	The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glyc...
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated	Human	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His)	Human	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-04683	CD47 Protein, Human, Recombinant	Human	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-00480	NCAM1 Protein, Human, Recombinant (His)	Human	HEK293
	NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293
	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells)	Human	Human Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His)	Human	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His)	Human	HEK293
	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-06411	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-05590	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli...
TMPY-04273	FGFR2 Protein, Human, Recombinant (aa 1-378, His)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-05383	NKp30/NCR3 Protein, Human, Recombinant (hFc)	Human	HEK293
	Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and...
TMPY-03969	SUSD4 Protein, Human, Recombinant (mFc)	Human	HEK293
	SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-04157	RANK/TNFRSF11A Protein, Human, Recombinant (His)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-03883	CD47 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a mem...
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-01656	VEGF183 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPJ-00390	FGFR2IIIb Protein, Human, Recombinant (hFc)	Human	Human Cells
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc)	Human	HEK293
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293
	Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPJ-00899	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)	Human	Human Cells
	Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. ERBB3 belon...
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)	Human	Baculovirus-Insect Cells
	Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5...
TMPY-00276	PLGF/PGF Protein, Human, Recombinant (mFc)	Human	HEK293
	PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 43.7 kDa. Accession number: P49763-3
TMPY-03960	COL9A1 Protein, Human, Recombinant (His)	Human	HEK293
	COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 34.2 kDa. Accession number: P20849-3
TMPY-05514	RANK/TNFRSF11A Protein, Human, Recombinant (mFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-03435	NCKIPSD Protein, Human, Recombinant (GST)	Human	E. coli
	NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
TMPY-05246	CD86 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co...
------------------------ More ------------------------

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

TMPY-01936

Species: Mouse

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (His)

TMPY-00949

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (aa 25-776, His & Avi), Biotinylated

TMPK-00446

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

TMPY-01937

Species: Mouse

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi)

TMPK-00445

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06620

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

TMPY-01069

Species: Human

Expression System: HEK293

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)

TMPY-03156

Species: Mouse,Rat

Expression System: HEK293

VEGFC Protein, Human, Recombinant (His)

TMPY-01007

Species: Human

Expression System: HEK293

VEGFD Protein, Human, Recombinant (His)

TMPY-01008

Species: Human

Expression System: HEK293

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)

TMPY-03155

Species: Mouse,Rat

Expression System: HEK293

VEGFD Protein, Mouse, Recombinant (His)

TMPY-03150

Species: Mouse

Expression System: HEK293

VEGFD Protein, Rat, Recombinant (hFc)

TMPY-03200

Species: Rat

Expression System: HEK293

VEGFD Protein, Mouse, Recombinant (hFc)

TMPY-02589

Species: Mouse

Expression System: HEK293

HNT/NTM Protein, Human, Recombinant (His)

TMPY-00357

Species: Human

Expression System: HEK293

FGF-8b Protein, Human, Recombinant

TMPY-06986

Species: Human

Expression System: E. coli

RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

TMPY-04142

Species: Human

Expression System: HEK293

CD45 Protein, Human, Recombinant (aa 26-577, His)

TMPY-05748

Species: Human

Expression System: HEK293

Mesothelin Protein, Human, Recombinant

TMPY-00132

Species: Human

Expression System: HEK293

CD47 Protein, Human, Recombinant, Biotinylated

TMPY-05191

Species: Human

Expression System: HEK293

Neuropilin-2 Protein, Human, Recombinant (hFc)

TMPY-03763

Species: Human

Expression System: HEK293

Neuropilin-2 Protein, Human, Recombinant (His)

TMPY-00892

Species: Human

Expression System: HEK293

Periostin/OSF-2 Protein, Human, Recombinant (His)

TMPY-01020

Species: Human

Expression System: HEK293

CD47 Protein, Human, Recombinant

TMPY-04683

Species: Human

Expression System: HEK293

PRSS3 Protein, Human, Recombinant (His)

TMPY-01897

Species: Human

Expression System: HEK293

CDCP1 Protein, Human, Recombinant (His)

TMPY-04298

Species: Human

Expression System: HEK293

NCAM1 Protein, Human, Recombinant (His)

TMPY-00480

Species: Human

Expression System: HEK293

CD86 Protein, Human, Recombinant (His)

TMPY-01180

Species: Human

Expression System: HEK293

IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

TMPJ-01099

Species: Human

Expression System: Human Cells

CD47 Protein, Human, Recombinant (aa 1-139, His)

TMPY-04935

Species: Human

Expression System: HEK293

GITR/TNFRSF18 Protein, Human, Recombinant (His)

TMPY-00072

Species: Human

Expression System: HEK293

GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06411

Species: Human

Expression System: HEK293

NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05590

Species: Human

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (aa 1-378, His)

TMPY-04273

Species: Human

Expression System: HEK293

NKp30/NCR3 Protein, Human, Recombinant (hFc)

TMPY-05383

Species: Human

Expression System: HEK293

SUSD4 Protein, Human, Recombinant (mFc)

TMPY-03969

Species: Human

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (His)

TMPY-04157

Species: Human

Expression System: HEK293

CD47 Protein, Human, Recombinant (hFc)

TMPY-03883

Species: Human

Expression System: HEK293

SMYD3 Protein, Human, Recombinant (GST)

TMPY-01268

Species: Human

Expression System: Baculovirus-Insect Cells

VEGF183 Protein, Human, Recombinant

TMPY-01656

Species: Human

Expression System: Baculovirus-Insect Cells

FGFR2IIIb Protein, Human, Recombinant (hFc)

TMPJ-00390

Species: Human

Expression System: Human Cells

CD45 Protein, Human, Recombinant (aa 26-577, hFc)

TMPK-00447

Species: Human

Expression System: HEK293

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

TMPK-00399

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

TMPJ-00899

Species: Human

Expression System: Human Cells

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

TMPY-04386

Species: Human

Expression System: Baculovirus-Insect Cells

PLGF/PGF Protein, Human, Recombinant (mFc)

TMPY-00276

Species: Human

Expression System: HEK293

COL9A1 Protein, Human, Recombinant (His)

TMPY-03960

Species: Human

Expression System: HEK293

RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

TMPY-05514

Species: Human

Expression System: HEK293

NCKIPSD Protein, Human, Recombinant (GST)

TMPY-03435

Species: Human

Expression System: E. coli

CD86 Protein, Human, Recombinant (His), Biotinylated

TMPY-05246

Species: Human

Expression System: HEK293

--------- More ---------

Cat No.	Product Name
L1610	FDA-Approved Kinase Inhibitor Library	263 compounds
	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L1600	Kinase Inhibitor Library	2700 compounds
	A unique collection of 2700 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;

Libraries

FDA-Approved Kinase Inhibitor Library

L1610

Compounds: 263

Kinase Inhibitor Library

L1600

Compounds: 2700