Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
2 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 197.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 556.00 | |
500 mg | In stock | $ 1,220.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. |
Targets&IC50 | FLT3:520 nM., RET kinase:880 nM |
Synonyms | NVP-AST 487 |
Molecular Weight | 529.56 |
Formula | C26H30F3N7O2 |
CAS No. | 630124-46-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (94.42 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AST 487 630124-46-8 Angiogenesis Apoptosis Cytoskeletal Signaling Tyrosine Kinase/Adaptors VEGFR Bcr-Abl c-RET FLT c-Kit inhibit NVP-AST487 RET CD135 SCFR NVP-AST 487 Inhibitor CD117 AST487 NVP-AST-487 Cluster of differentiation antigen 135 FLT3 Vascular endothelial growth factor receptor AST-487 Fms like tyrosine kinase 3 inhibitor