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Angiogenesis VEGFR Fruquintinib

Fruquintinib

Catalog No. T2656   CAS 1194506-26-7
Synonyms: HMPL-013

Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Fruquintinib, CAS 1194506-26-7
Pack Size Availability Price/USD Quantity
2 mg In stock 38.00
5 mg In stock 48.00
10 mg In stock 77.00
25 mg In stock 119.00
50 mg In stock 150.00
100 mg In stock 263.00
1 mL * 10 mM (in DMSO) In stock 53.00
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Purity 98.84%
Purity 100.00%
Purity 99.89%
Purity 99.43%
Biological Description
Chemical Properties
Storage & Solubility Information
Description Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities.
Targets&IC50 VEGFR
Synonyms HMPL-013
Purity 98.84%
Molecular Weight 393.39
Formula C21H19N3O5
CAS No. 1194506-26-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 7.75 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Gu Y, et al. Y ChemOthers Pharmacol. 2014 Jul;74(1):95-115.

Related compound libraries

This product is contained In the following compound libraries:
Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-Cancer Compound Library Clinical Compound Library Tyrosine Kinase Inhibitor Library Cytokine Inhibitor Library Kinase Inhibitor Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Angiogenesis related Compound Library Anti-Obesity Compound Library Anti-Cancer Active Compound Library Anti-Cancer Drug Library Drug Repurposing Compound Library Target-Focused Phenotypic Screening Library Anti-Lung Cancer Compound Library Drug-induced Liver Injury (DILI) Compound Library NMPA-Approved Drug Library FDA-Approved & Pharmacopeia Drug Library Anti-Breast Cancer Compound Library Anti-Pancreatic Cancer Compound Library Anti-Fibrosis Compound Library

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Dose Conversion

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.