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Catalog No. T2032   CAS 211555-08-7
Synonyms: Janex 3

WHI-P180 is a potent <a href="/target/EGFR" style="display: inline; color: #c13a36">EGFR</a> and <a href="/target/CDK" style="display: inline; color: #c13a36">CDK</a>2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
WHI-P180, CAS 211555-08-7
Pack Size Availability Price/USD Quantity
2 mg In stock $ 159.00
5 mg In stock $ 247.00
10 mg In stock $ 373.00
50 mg In stock $ 879.00
1 mL * 10 mM (in DMSO) In stock $ 258.00
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Purity: 98%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
Targets&IC50 EGFR:4.0μM, CDK2:1.0 μM
Synonyms Janex 3
Molecular Weight 297.314
Formula C16H15N3O3
CAS No. 211555-08-7


Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. An R, et al. Pharm Res. 2009 Feb;26(2):449-58.

Related compound libraries

This product is contained In the following compound libraries:
Immunology/Inflammation Compound Library Anti-Colorectal Cancer Compound Library Anti-Cardiovascular Disease Compound Library Anti-Liver Cancer Compound Library JAK-STAT Compound Library Cell Cycle Compound Library Anti-Cancer Compound Library Cytokine Inhibitor Library Apoptosis Compound Library Anti-Pancreatic Cancer Compound Library

Related Products

Related compounds with same targets
SU14813 maleate Sprengerinin C Riddelline Penduletin Licoricidin Ginsenoside Rk2 Brivanib GSK1904529A

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box


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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box


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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.


Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.


WHI-P180 211555-08-7 Angiogenesis Apoptosis Cell Cycle/Checkpoint JAK/STAT signaling Tyrosine Kinase/Adaptors VEGFR EGFR c-RET CDK WHI-P-180 HER1 Janex3 WHI P180 RET Vascular endothelial growth factor receptor Inhibitor Janex-3 WHIP180 Janex 3 inhibit ErbB-1 Epidermal growth factor receptor inhibitor