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WHI-P180

Catalog No. T2032   CAS 211555-08-7
Synonyms: Janex 3

WHI-P180 is a potent <a href="/target/EGFR" style="display: inline; color: #c13a36">EGFR</a> and <a href="/target/CDK" style="display: inline; color: #c13a36">CDK</a>2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
WHI-P180, CAS 211555-08-7
Pack Size Availability Price/USD Quantity
2 mg In stock $ 159.00
5 mg In stock $ 247.00
10 mg In stock $ 373.00
50 mg In stock $ 879.00
1 mL * 10 mM (in DMSO) In stock $ 258.00
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Purity: 98%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.
Targets&IC50 EGFR:4.0μM, CDK2:1.0 μM
Synonyms Janex 3
Molecular Weight 297.314
Formula C16H15N3O3
CAS No. 211555-08-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. An R, et al. Pharm Res. 2009 Feb;26(2):449-58.

Related compound libraries

This product is contained In the following compound libraries:
Immunology/Inflammation Compound Library Anti-Colorectal Cancer Compound Library Anti-Cardiovascular Disease Compound Library Anti-Liver Cancer Compound Library JAK-STAT Compound Library Cell Cycle Compound Library Anti-Cancer Compound Library Cytokine Inhibitor Library Apoptosis Compound Library Anti-Pancreatic Cancer Compound Library

Related Products

Related compounds with same targets
SU14813 maleate Sprengerinin C Riddelline Penduletin Licoricidin Ginsenoside Rk2 Brivanib GSK1904529A

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

WHI-P180 211555-08-7 Angiogenesis Apoptosis Cell Cycle/Checkpoint JAK/STAT signaling Tyrosine Kinase/Adaptors VEGFR EGFR c-RET CDK WHI-P-180 HER1 Janex3 WHI P180 RET Vascular endothelial growth factor receptor Inhibitor Janex-3 WHIP180 Janex 3 inhibit ErbB-1 Epidermal growth factor receptor inhibitor