Search Result

Search Results for " pra "

386

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T65838	Fmoc-Pra-OH
	Fmoc-Pra-OH is an amino acid derivative and has a wide range of applications in life science related research.
T65866	Fmoc-D-Pra-OH
	Fmoc-D-Pra-OH is an amino acid derivative and has a wide range of applications in life science related research.
T80560	Tulisokibart	PRA-023,PRA023
	Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody that targets TNFSF15/TL1A, with potential applications in researching various inflammatory and fibrotic diseases, including Crohn's Disease (CD) [1] [2].
T12285	Ebopiprant	OBE022,OBE-022	Others
	Ebopiprant (OBE022) is an orally available, selective and potent prostaglandin F2α (PGF2α) receptor antagonist that interferes with the binding of PGF0126α to the FPR and can be used in the study of obesity.		Others
T19526	Pradefovir mesylate	Pradefovir mesilate,Remofovir mesylate,Hepavir B	P450
	Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM.		P450
T1756L	Ilaprazole	IY81149,IY 81149,IY-81149	Proton pump , TOPK
	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...		Proton pump , TOPK
T2262	Itanapraced	CHF5074,CSP-1103	Beta Amyloid , Gamma-secretase
	Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).		Beta Amyloid , Gamma-secretase
T8388	Vonoprazan	TAK-438 (free base)	Proton pump
	Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis		Proton pump
T68063	Elopiprazole	DU 29840	Others
	Elopiprazole(DU 29840) is an anti-neurological compound that can be used to study neurological disorders.		Others
T67810	Tampramine		Norepinephrine
	Tampramine is a selective norepinephrine reuptake inhibitor that shows a low affinity for adrenergic, histaminergic and muscarinic receptors. Tampramine is a candidate compound for the treatment of forced swimming test (...		Norepinephrine
T14390L	(2R,3S)-Azelaprag		Apelin receptor
	(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...		Apelin receptor
T27138	Declopramide	OXI-104,IMO-B,3-Chloroprocainamide	Apoptosis
	Declopramide (OXI-104) is a novel chemosensitizer with antitumor activity that induces apoptosis and can be used to study colorectal cancer and inflammatory bowel disease.		Apoptosis
T68036	Carprazidil		Others
	Carprazidil is a potent vasodilator used to treat severe hypertension and mild heart failure.		Others
T25982	Pramiconazole	R-126638,R126638,R 126638,Azoline	Antifungal
	Pramiconazole (R126638) is an orally available antifungal compound.Pramiconazole is a candidate for the treatment of dermatophytes and cutaneous yeast infections in seborrheic dermatitis.		Antifungal
T7746	Eltoprazine dihydrochloride		Others
	Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD pati...		Others
T17030	Tegoprazan		ATPase , Proton pump
	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...		ATPase , Proton pump
T9128	N-Desmethyltrimipramine		Others
	N-Desmethyltrimipramine is a biochemical.		Others
T8690	Brexpiprazole HCl	OPC 34712 dihydrochloride	Others
	Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug.		Others
T0757	Omeprazole	Losec,Prilosec,H 16868,Antra	Proton pump , Phospholipase , Antibacterial , Autophagy
	Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).		Proton pump , Phospholipase , Antibacterial , Autophagy
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T11011	Dexpramipexole dihydrochloride	KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,(R)-Pramipexole dihydrochloride	Dopamine Receptor
	Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and is a weak non-ergoline dopamine agonist.		Dopamine Receptor
T14319	Aripiprazole Lauroxil		Dopamine Receptor , 5-HT Receptor
	Aripiprazole lauroxil, the N-acyloxymethyl prodrug form of aripiprazole, a long-acting injectable (LAI) antipsychotic. Aripiprazole lauroxil is cleaved by esterases in vivo to N-hydroxymethyl aripiprazole (lauric acid), ...		Dopamine Receptor , 5-HT Receptor
T0159	Pranoprofen	Pyranoprofen	Apoptosis , COX , PGE Synthase , Prostaglandin Receptor
	Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.		Apoptosis , COX , PGE Synthase , Prostaglandin Receptor
T36949	Niaprazine		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
	Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...		5-HT Receptor , Adrenergic Receptor , Histamine Receptor
T0031L	Ziprasidone hydrochloride	CP-88059 hydrochloride,CP-88059,Ziprasidone HCl	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
	Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T0694	Pranlukast	ONO-1078	Leukotriene Receptor , IL Receptor , Others , TNF , NF-κB , LTR
	Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered aller...
T14204	6-Iodopravadoline	AM630	Cannabinoid Receptor
	6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.		Cannabinoid Receptor
T3520	Setipiprant	KYTH-105,ACT-129968	GPR , Prostaglandin Receptor
	Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in vari...		GPR , Prostaglandin Receptor
T1189	Milnacipran hydrochloride	Milnacipran HCl,Savella,Dalcipran	Serotonin Transporter , Norepinephrine
	Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy...		Serotonin Transporter , Norepinephrine
T1566	Aripiprazole	OPC-14597	5-HT Receptor
	Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a...		5-HT Receptor
T0991	Desipramine hydrochloride	NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
	Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T6547	Ipratropium Bromide	Sch 1000,Itrop,Atrovent	AChR
	Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.		AChR
T17232	Vidupiprant	AMG 853	Prostaglandin Receptor
	Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma.		Prostaglandin Receptor
T21371	Apraclonidine hydrochloride	Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum	Adrenergic Receptor
	Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco...		Adrenergic Receptor
TQ0277	Pralsetinib	Blu667	c-RET
	Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion).		c-RET
T12309	Omeprazole metabolite Omeprazole sulfone	Omeprazole sulphone,Omeprazole sulfone	Others
	Omeprazole metabolite Omeprazole sulfone can inhibit proton pump.		Others
T20828	Citalopram	Cipram,Lu 10-171,Lu-10-171 Lu10-171	5-HT Receptor
	Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enant...		5-HT Receptor
T11827	Pradigastat	ANJ908,LCQ908-NXA,LCQ908A,LCQ-908	Transferase
	Pradigastat (LCQ-908) is an orally active, potent and selective diacylglycerol acyltransferase 1 (DGAT1) inhibitor for the treatment of constipation, which may be used in the study of obesity and diabetes.		Transferase
T77122	Praluzatamab		Others
	Praluzatamab is a monoclonal antibody targeting an activated white blood cell adhesion molecule (ALCAM/CD116). Praluzatamab is a naked antibody to Praluzatamab ravtansine and can be used to synthesize antibody active mol...		Others
T10138	4-Desmethoxy Omeprazole		Drug Metabolite
	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).		Drug Metabolite
T1476	Pramipexole	SND 919	Dopamine Receptor
	Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...		Dopamine Receptor
T22406	Prazosin	Prazosine,Furazosin,Prazocin	Adrenergic Receptor
	Prazosin (Prazosine), an α1-blocker, acts as an inverse agonist at alpha-1 adrenergic receptors and is used to treat hypertension.		Adrenergic Receptor
T23380	Sonepiprazole		Dopamine Receptor
	Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4...		Dopamine Receptor
T10221	Abeprazan hydrochloride	DWP14012 hydrochloride,Fexuprazan hydrochloride	Proton pump
	Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat...		Proton pump
T4577	Cariprazine	RGH-188	Dopamine Receptor , 5-HT Receptor
	Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).		Dopamine Receptor , 5-HT Receptor
T1756	Ilaprazole sodium	IY-81149 sodium	Proton pump , TOPK
	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...		Proton pump , TOPK
T4616	Metoclopramide	5-Chloro-2-methoxyprocainamide	Dopamine Receptor , 5-HT Receptor
	Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ...		Dopamine Receptor , 5-HT Receptor
T23302	(S)-(-)-Propranolol hydrochloride		Adrenergic Receptor
	(S)-(-)-Propranolol hydrochloride is an adrenergic receptor antagonist with potential anticancer activity that may improve the prognosis of burn patients.		Adrenergic Receptor
T13448	(R)-(-)-Rolipram	(R)-Rolipram,(-)-Rolipram	DNA-PK , Others
	(R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor.		DNA-PK , Others
T20626	Esomeprazole		Proton pump , Cysteine Protease
	Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).		Proton pump , Cysteine Protease

Compounds

Synonym: PRA-023,PRA023

Target:

Ebopiprant

T12285

Synonym: OBE022,OBE-022

Target: Others

Pradefovir mesylate

T19526

Synonym: Pradefovir mesilate,Remofovir mesylate,Hepavir B

Target: P450

Ilaprazole

T1756L

Synonym: IY81149,IY 81149,IY-81149

Target: Proton pump, TOPK

Itanapraced

T2262

Synonym: CHF5074,CSP-1103

Target: Beta Amyloid, Gamma-secretase

Vonoprazan

T8388

Synonym: TAK-438 (free base)

Target: Norepinephrine

(2R,3S)-Azelaprag

T14390L

Synonym:

Target: Apelin receptor

Declopramide

T27138

Synonym: OXI-104,IMO-B,3-Chloroprocainamide

Synonym: R-126638,R126638,R 126638,Azoline

Target: Antifungal

Eltoprazine dihydrochloride

Target: ATPase, Proton pump

N-Desmethyltrimipramine

Synonym: OPC 34712 dihydrochloride

Target: Others

Omeprazole

T0757

Synonym: Losec,Prilosec,H 16868,Antra

Target: Proton pump, Phospholipase, Antibacterial, Autophagy

Esomeprazole Magnesium

T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

Dexpramipexole dihydrochloride

T11011

Synonym: KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,(R)-Pramipexole dihydrochloride

Target: Dopamine Receptor

Aripiprazole Lauroxil

T14319

Synonym:

Target: Dopamine Receptor, 5-HT Receptor

Pranoprofen

T0159

Synonym: Pyranoprofen

Target: Apoptosis, COX, PGE Synthase, Prostaglandin Receptor

Niaprazine

T36949

Synonym:

Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Ziprasidone hydrochloride

T0031L

Synonym: CP-88059 hydrochloride,CP-88059,Ziprasidone HCl

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor

Pranlukast

T0694

Synonym: ONO-1078

Target: Leukotriene Receptor, IL Receptor, Others, TNF, NF-κB, LTR

6-Iodopravadoline

T14204

Synonym: AM630

Target: Cannabinoid Receptor

Setipiprant

T3520

Synonym: KYTH-105,ACT-129968

Target: GPR, Prostaglandin Receptor

Milnacipran hydrochloride

T1189

Synonym: Milnacipran HCl,Savella,Dalcipran

Target: Serotonin Transporter, Norepinephrine

Aripiprazole

T1566

Synonym: OPC-14597

Target: 5-HT Receptor

Desipramine hydrochloride

T0991

Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor

Ipratropium Bromide

T6547

Synonym: Sch 1000,Itrop,Atrovent

Target: Prostaglandin Receptor

Apraclonidine hydrochloride

T21371

Synonym: Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum

Target: Adrenergic Receptor

Omeprazole metabolite Omeprazole sulfone

T12309

Synonym: Omeprazole sulphone,Omeprazole sulfone

Target: Others

Citalopram

T20828

Synonym: Cipram,Lu 10-171,Lu-10-171 Lu10-171

Target: 5-HT Receptor

Pradigastat

T11827

Synonym: ANJ908,LCQ908-NXA,LCQ908A,LCQ-908

4-Desmethoxy Omeprazole

T10138

Synonym:

Target: Drug Metabolite

Pramipexole

T1476

Synonym: SND 919

Target: Dopamine Receptor

Prazosin

T22406

Synonym: Prazosine,Furazosin,Prazocin

Target: Adrenergic Receptor

Sonepiprazole

T23380

Synonym:

Target: Dopamine Receptor

Abeprazan hydrochloride

T10221

Synonym: DWP14012 hydrochloride,Fexuprazan hydrochloride

Target: Dopamine Receptor, 5-HT Receptor

Ilaprazole sodium

T1756

Synonym: IY-81149 sodium

Target: Proton pump, TOPK

Metoclopramide

T4616

Synonym: 5-Chloro-2-methoxyprocainamide

Target: Dopamine Receptor, 5-HT Receptor

(S)-(-)-Propranolol hydrochloride

T23302

Synonym:

Target: Adrenergic Receptor

(R)-(-)-Rolipram

T13448

Synonym: (R)-Rolipram,(-)-Rolipram

Target: DNA-PK, Others

Esomeprazole

T20626

Synonym:

Target: Proton pump, Cysteine Protease

Cat No.	Product Name	Synonyms	Targets
T6S1418	Praeruptorin C		Antioxidant , Calcium Channel
	1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ...		Antioxidant , Calcium Channel
T1084	Apramycin sulfate	Nebramycin II,Ai3-29795	Antibacterial , Antibiotic
	Apramycin sulfate (Nebramycin II) is an aminoglycoside antibiotic.		Antibacterial , Antibiotic
T3777	Praeruptorin A	(+)-Praeruptorin A	CaMK , NF-κB
	Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or...		CaMK , NF-κB
T1045	Trimipramine maleate	Surmontil maleate	Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
	Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T21651	Lansoprazole sodium	Lansoprazole (sodium), AG-1749 sodium	Proton pump , Phospholipase , Antibacterial
	Lansoprazole sodium (Lansoprazole (sodium)) is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and peptic ulcer disease.		Proton pump , Phospholipase , Antibacterial
T31708	Ethyl caprate	Decanoic acid, ethyl ester,Ethyl decylate,Ethyl decanoate,Ethyl caprinate,Capric acid ethyl ester
	Ethyl caprate, also known as Ethyl decanoate, is a fatty acid ester formed from capric acid and ethanol. This ester is a frequent product of fermentation during winemaking, especially at temperatures above 15 °C.
TN3231	Pratol	7-Hydroxy-4'-methoxyflavone	Others
	Pratol (7-Hydroxy-4'-methoxyflavone) significantly increased melanin content and tyrosinase activity in the cells without being cytotoxic.		Others
T0672	Pravastatin sodium	CS-514 Sodium,CS-514 (sodium)	Ferroptosis , HMG-CoA Reductase , Autophagy
	Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.		Ferroptosis , HMG-CoA Reductase , Autophagy
T6S1423	Praeruptorin B		Others
	1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.		Others
T0185	Escitalopram	Seroplex,S-(+)-Citalopram,(S)-Citalopram	Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
	Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T4S1419	(±)-Praeruptorin A	Praeruptorin A,(-)-Praeruptorin A	p38 MAPK , Calcium Channel , Akt
	1. (±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation 2. Praeruptorin A has the potential to inhibit migration/fusion ...		p38 MAPK , Calcium Channel , Akt
T4S1422	Praeruptorin E		Others , Calcium Channel
	1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit...		Others , Calcium Channel
T2A2509	Laurocapram	Tranzone,Azone,N-Lauryl caprolactam,N-0252,N-Dodecylcaprolactam	Others
	Laurocapram (N-Lauryl caprolactam) is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemic...		Others
TN2100	Pratensein		Others , NF-κB
	Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.		Others , NF-κB
TN4924	Rubiprasin A		Others
	Rubiprasin A is a natural product from Rubia cordifolia var. pratensis.		Others
TN4819	(-)-Praeruptorin A		ATPase , IL Receptor , Calcium Channel , P-gp
	(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can ...		ATPase , IL Receptor , Calcium Channel , P-gp
T81411	Praeroside IV
	Praeroside IV, a compound extractable from the roots of Angelica furcijuga, is utilized in the research of D-GalN/LPS-induced liver injury [1].
TN5882	Praeroside II
	Praeroside II shows inhibitory activity of NO production in macrophages.
T40404	Caprazamycin
	Caprazamycin is a liponucleoside antibiotic.
T4984	Cefozopran hydrochloride	SCE-2787 hydrochloride	Antifungal
	Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin. is a cell wall biosynthesis inhibitor with a broad spectrum of activity against Gram-positive and Gram-negative bacteria.		Antifungal
T82781	Caprazol
	Caprazol constitutes the central framework of the antibiotic Caprazamycin [1].
TN4925	Rubiprasin B		Others
	Rubiprasin B is a natural product from Rubia cordifolia var. pratensis.		Others
T21111	Dimethyl capramide	N,N-Dimethyldecanamide,AI3-34960,N,N-Dimethylcapylamide,N,N-Dimethyldecanoamide,N,N-Dimethylcapramide
	Dimethyl capramide is a biochemical.
TN2099	Pratensein-7-O-β-D-glucopyranoside	Pratensein 7-O-glucopyranoside	Others
	Pratensein 7-O-glucopyranoside is a natural product		Others
TN5556	Caprarioside	8-O-Benzoylharpagide
	Caprarioside is a natural product for research related to life sciences. The catalog number is TN5556 and the CAS number is 1151862-69-9.
T21196	Isopropyl caprate	Isopropyl decanoate,Decanoic Acid Isopropyl Ester
	Isopropyl caprate is a biochemical.
T73205	Praelolide
	Praelolide, a potent Nrf2 activator, disrupts Keap1-Nrf2 protein-protein interactions through noncovalent binding to Keap1, inhibiting osteoclastogenesis and the production of reactive oxygen species (ROS). With its pote...
T4S1421	Praeruptorin B	Praeruptorin D	NPC1L1 , Fatty Acid Synthase
	Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway.		NPC1L1 , Fatty Acid Synthase

Natural Products

Praeruptorin C

T6S1418

Synonym:

Target: Antioxidant, Calcium Channel

Apramycin sulfate

T1084

Synonym: Nebramycin II,Ai3-29795

Target: Antibacterial, Antibiotic

Praeruptorin A

T3777

Synonym: (+)-Praeruptorin A

Target: CaMK, NF-κB

Trimipramine maleate

T1045

Synonym: Surmontil maleate

Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor

Lansoprazole sodium

T21651

Synonym: Lansoprazole (sodium), AG-1749 sodium

Target: Proton pump, Phospholipase, Antibacterial

Ethyl caprate

T31708

Synonym: Decanoic acid, ethyl ester,Ethyl decylate,Ethyl decanoate,Ethyl caprinate,Capric acid ethyl ester

Target:

Pratol

TN3231

Synonym: 7-Hydroxy-4'-methoxyflavone

Target: Others

Pravastatin sodium

T0672

Synonym: CS-514 Sodium,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram

Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor

(±)-Praeruptorin A

T4S1419

Synonym: Praeruptorin A,(-)-Praeruptorin A

Target: p38 MAPK, Calcium Channel, Akt

Praeruptorin E

T4S1422

Synonym:

Target: Others, Calcium Channel

Laurocapram

T2A2509

Synonym: Tranzone,Azone,N-Lauryl caprolactam,N-0252,N-Dodecylcaprolactam

Target: Others, NF-κB

Target: ATPase, IL Receptor, Calcium Channel, P-gp

Cefozopran hydrochloride

T4984

Synonym: SCE-2787 hydrochloride

Synonym: N,N-Dimethyldecanamide,AI3-34960,N,N-Dimethylcapylamide,N,N-Dimethyldecanoamide,N,N-Dimethylcapramide

Target:

Pratensein-7-O-β-D-glucopyranoside

TN2099

Synonym: Pratensein 7-O-glucopyranoside

Target: Others

Caprarioside

TN5556

Synonym: 8-O-Benzoylharpagide

Target:

Isopropyl caprate

T21196

Synonym: Isopropyl decanoate,Decanoic Acid Isopropyl Ester

Synonym: Praeruptorin D

Target: NPC1L1, Fatty Acid Synthase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01094	S100A6 Protein, Mouse, Recombinant	Mouse	E. coli
	S100A6 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10 kDa and the accession number is P14069.
TMPY-01339	S100A6 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	S100A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12 kDa and the accession number is P06703.
TMPY-00912	S100A6 Protein, Human, Recombinant	Human	E. coli
	S100A6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 10.2 kDa and the accession number is P06703.
TMPK-01455	HLA-A02:01&B2M&PRA*ME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01406	HLA-A02:01&B2M&PRA*ME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPY-06149	Phl p 5 Protein, Phleum pratense, Recombinant (His)	Phleum pratense	HEK293 Cells
	Phl p 5 Protein, Phleum pratense, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q40960-1.
TMPY-03048	PRAP1 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PRAP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 41.4 kDa and the accession number is AAL16670.1.
TMPJ-01298	PRADC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PRADC1, also known as C2orf7 or PAP21, is short for Protease-associated domain-containing protein 1. It is a 188 aa. with a 21 aa. signal, and the 171 located Asn can be glycosylated. PRADC1 has two mutagenesis which are...
TMPY-03076	PRAP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PRAP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.4 kDa and the accession number is AAL16670.1.
TMPK-01447	HLA-A02:01&B2M&PRA*ME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01454	HLA-A02:01&B2M&PRA*ME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPY-06016	Phl p 5 Protein, Phleum pratense, Recombinant	Phleum pratense	E. coli
	Phl p 5 Protein, Phleum pratense, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28.7 kDa and the accession number is Q40960-1.
TMPH-03094	Phl p 5b Protein, Phleum pratense, Recombinant (His & SUMO)	Phleum pratense	E. coli
	Has ribonuclease activity. May be involved in host-pathogen interactions. Phl p 5b Protein, Phleum pratense, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecul...
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated...
TMPH-00338	PRA1 Protein, Candida albicans, Recombinant (His)	Candida albicans	P. pastoris (Yeast)
	PRA1 Protein, Candida albicans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.4 kDa and the accession number is P87020.
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTP...
TMPH-01651	PRAME Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	PRAME Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 59.9 kDa and the accession number is P78395.
TMPH-01650	PRAME Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation. The CRL2(PRAME) complex mediates ubiquitination a...
TMPH-03093	Phl p 5a Protein, Phleum pratense, Recombinant (His & SUMO)	Phleum pratense	E. coli
	N/A. Phl p 5a Protein, Phleum pratense, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.5 kDa and the accession number is Q40962.
TMPK-00696	PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)	Human	Baculovirus Insect Cells
	The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-...
TMPY-01555	PRAC Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	The PRAC gene is located on chromosome 17 at position 17q21, about 4 kbp downstream from the homeodomain Hoxb-13 gene. The pathogenesis of PCa may be due to the expression levels of PRAC protein, and this protein can ser...
TMPY-06015	Phl p 2 Protein, Phleum pratense, Recombinant (His)	Phleum pratense	HEK293 Cells
	Phl p 2 Protein, Phleum pratense, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.1 kDa and the accession number is P43214-1.
TMPH-03095	Phl p 6 Protein, Phleum pratense, Recombinant (His & Myc)	Phleum pratense	E. coli
	Phl p 6 Protein, Phleum pratense, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.2 kDa and the accession number is P43215.
TMPK-01441	HLA-A02:01&B2M&PRA*ME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPH-03096	Profilin 2 Protein, Phleum pratense, Recombinant (His & Myc)	Phleum pratense	E. coli
	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the forma...