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Ilaprazole sodium

Catalog No. T1756 CAS 172152-50-0

Synonyms: IY-81149 sodium, 艾普拉唑钠

Ilaprazole, a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.

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Ilaprazole sodium, CAS 172152-50-0

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	IY-81149 sodium, 艾普拉唑钠
Molecular Weight	388.42
Formula	C19H17N4NaO2S
CAS No.	172152-50-0

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 71 mg/mL(182.8 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Cardiovascular Disease Compound Library Inhibitor Library Ion Channel Inhibitor Library Immunology/Inflammation Compound Library Covalent Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-COVID-19 Compound Library Kinase Inhibitor Library

Related Products

Related compounds with same targets

Vonoprazan Bafilomycin A1 Tenatoprazole Bamaquimast Omeprazole sulfide Vonoprazan Fumarate Pumaprazole 5-Hydroxylansoprazole

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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