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Ilaprazole

Catalog No. T1756L CAS 172152-36-2

Synonyms: IY 81149, IY-81149, 艾普拉唑, IY81149

Ilaprazole is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the development of reflux oesophagitis.

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Ilaprazole, CAS 172152-36-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Ilaprazole is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the development of reflux oesophagitis.
Targets&IC50	H+/K+-ATPase:6.0 μM (IC50)

Synonyms	IY 81149, IY-81149, 艾普拉唑, IY81149
Molecular Weight	366.44
Formula	C19H18N4O2S
CAS No.	172152-36-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 35 mg/mL (95.51 mM)

Ethanol: 12.5 mg/mL (34.11 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zhou G, Shi S, Zhang W, Tan Z, Chen Y, Guo D, Zhou H, Hu H, Tan J. Identification of ilaprazole metabolites in human urine by HPLC-ESI-MS/MS and HPLC-NMR experiments. Biomed Chromatogr. 2010 Oct;24(10):1130-5. doi: 10.1002/bmc.1416. PubMed PMID: 20352613. 2. Scarpignato C, Pelosini I, Di Mario F. Acid suppression therapy: where do we go from here? Dig Dis. 2006;24(1-2):11-46. Review. PubMed PMID: 16699262.

Related Products

Related compounds with same targets

OTS964 hydrochloride OTS514 OTS514 hydrochloride Ilaprazole Ilaprazole sodium HI-TOPK-032 Cephradine

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ilaprazole 172152-36-2 MAPK信号通路离子通道 TOPK Proton pump Proton Pump oral cancer ulcers Inhibitor inhibit pump acid IY81149 gastric IY-81149 IY 81149 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.