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Omeprazole

Catalog No. T0757 CAS 73590-58-6

Synonyms: Prilosec, H 16868, 奥美拉唑, Antra, 奥美拉挫, Losec

Omeprazole is a proton pump inhibitor (PPI), Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Omeprazole, CAS 73590-58-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Omeprazole is a proton pump inhibitor (PPI), Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

Synonyms	Prilosec, H 16868, 奥美拉唑, Antra, 奥美拉挫, Losec
Molecular Weight	345.42
Formula	C17H19N3O3S
CAS No.	73590-58-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

1eq. HCl: 17.3 mg/mL (50 mM)

DMSO: 34.5 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dzeletovic N, et al. J Biol Chem, 1997, 272(19), 12705-12713. 2. Scaringi L, et al. Scand J Immunol, 1996, 44(3), 204-214. 3. Hyun JJ, et al. Int J Mol Med, 2010, 26(6), 877-883. 4. Karam SM, et al. Am J Physiol, 1994, 266(4 Pt 1), G745-758. 5. Kang D, Pang X, Lian W, et al. Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches[J]. RSC Advances. 2018 Jan 8(10): 5286-5297.

Citations

1. Kang D, Pang X, Lian W, et al. Discovery of VEGFR2 inhibitors by integrating naïve Bayesian classification, molecular docking and drug screening approaches. RSC Advances. 2018 Jan 8(10): 5286-5297.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Autophagy Compound Library Anti-Cardiovascular Disease Compound Library Inhibitor Library Drug-induced Liver Injury (DILI) Compound Library Ion Channel Inhibitor Library Immunology/Inflammation Compound Library Covalent Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library

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Related compounds with same targets

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Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Omeprazole 73590-58-6 代谢离子通道微生物学自噬 Antibacterial Autophagy Phospholipase Proton pump H16868 Antra inhibit H-16868 Inhibitor Bacterial Losec Proton Pump H 16868 Prilosec inhibitor

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