Search Result

Search Results for " pparγ "

145

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T61417	PPARγ agonist 7
	PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It specifically stimulates adiponectin production in human bone marrow mesenchymal s...
T79678	PPARγ-IN-2		PPAR
	"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes. Furthermore, PPARγ-IN-2 counteracts obesity and associated metabolic syndrome induced by a...		PPAR
T63561	PPARγ agonist 5
	PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.
T61465	PPARγ agonist 3
	PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ. This compound does not exhibit cytotoxicity towards both non-resistant and resistant cells. Notably, PPARγ agonist 3 demonstrates a...
T79182	PPARγ agonist 8		PPAR
	PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator response element (PPRE)-luciferase activity with an effective con...		PPAR
T62581	PPARγ agonist 6
	PPARγ agonist 6 (Compound 12) is a potent agonist of selective PPARγ. PPARγ agonist 6 has potential for cancer disease research.
T61731	PPARγ agonist 4
	PPARγ agonist 4 (Compound 18b), a potent and selective PPARγ agonist, demonstrates antitumor efficacy only when used in conjunction with Imatinib. Notably, PPARγ agonist 4 does not exhibit cytotoxic effects on either non...
T63514	PPARγ agonist 1
	PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects. pparγ agonist 1 has shown research potential in cardiovascular diseases assoc...
T61743	PPARγ agonist 2
	PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ. It exhibits significant potential for utilization in metabolic disease research [1].
T75009	PPARγ/GR modulator 1
	PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits Ki values of 3.3 and 33.6 μM, respectively. This compound is...
T62554	PPARγ phosphorylation inhibitor 1
	PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects. PPARγ phosphorylation inhibitor 1 exhibited inhibition of CDK5-mediated PPARγ Ser273 phosphorylatio...
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T4353	SR-18292	SR 18292	Autophagy
	SR-18292 is an inhibitor of PPAR gamma coactivator-1α (PGC-1α), which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.		Autophagy
T1802	ZLN005		Autophagy
	ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.		Autophagy
T21955	GQ-16		PPAR
	GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.		PPAR
T8763	PTGR2-IN-1	PTGR2-IN-22	Others
	PTGR2-IN-1 is a potent inhibito of PTGR2r(IC50 : 0.7 μM). It increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.		Others
T6829	EPI-001	EPI001,EPI 001	Apoptosis , Androgen Receptor , PPAR
	EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.		Apoptosis , Androgen Receptor , PPAR
T0214	Pioglitazone	U 72107	Ferroptosis , PPAR
	Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.		Ferroptosis , PPAR
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T6646	Rosiglitazone hydrochloride	BRL-49653 HCl,Rosiglitazone HCl	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
T67936	BAY-0069		PPAR
	BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research.		PPAR
T23389	SR1664	SR 1664	PPAR
	SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR...		PPAR
T2260	GW9662	TIMTEC-BB SBB006523,GW 9662	PPAR
	GW9662 (TIMTEC-BB SBB006523) is a specific PPARγ antagonist (IC50: 3.3 nM, in a cell-free assay), with 100 to 1000-fold functional selectivity for PPARγ than PPARα/δ in cells.		PPAR
T38715	MSDC-0602K	MSDC-0602K,Azemiglitazone potassium	PPAR
	MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (...		PPAR
T3170	Troglitazone	CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay	Apoptosis , Ferroptosis , PPAR , Autophagy
	Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.		Apoptosis , Ferroptosis , PPAR , Autophagy
T12835	Saroglitazar	Lipaglyn	PPAR
	Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.		PPAR
T6689	T0070907		PPAR
	T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.		PPAR
T8374	LJ570		PPAR
	LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)		PPAR
T14176	Aleglitazar	RO0728804,R1439	PPAR
	Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes.		PPAR
T16074	Mifobate	SR-202	PPAR
	Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].		PPAR
T12834	Saroglitazar Magnesium		Others
	Saroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARα (EC50 0.65pM) and moderate activation against PPARγ (EC50 3 nM).		Others
T67933	BAY-4931		PPAR
	BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.		PPAR
T17044	Tesaglitazar		PPAR
	Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα and human PPARα were 13.4 μM and 3.6 μM, respectively, and 0...		PPAR
TQ0120	CDDO-Im	RTA-403,CDDO-Imidazolide,TP-235	Others , Ferroptosis , Nrf2 , PPAR
	CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).		Others , Ferroptosis , Nrf2 , PPAR
T15453	GW7647		PPAR
	GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ, and PPARδ, respectively).		PPAR
T7395	Lanifibranor	IVA337	PPAR
	Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα, PPARβ, and PPARγ, respectively, for transactivation activ...		PPAR
T15581	Inolitazone	RS5444,Efatutazone,CS-7017	PPAR
	Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.		PPAR
T0214L	Pioglitazone hydrochloride	U-72107E,AD 4833,U 72107A,Pioglitazone HCl	Ferroptosis , PPAR
	Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic activity.		Ferroptosis , PPAR
T19710	Ciglitazone	Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878	Apoptosis , p38 MAPK , PPAR
	Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelia...		Apoptosis , p38 MAPK , PPAR
T21764	MCC-555	Isaglitazone,Netoglitazone	PPAR
	MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.		PPAR
T24827	SR 16832	SR-16832,SR16832	PPAR
	SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907.		PPAR
T19211	BM152054		Others
	BM152054 is a potent PPARγ ligand that induces glucose utilization in peripheral tissues by enhancing insulin action.		Others
T15440	GSK376501A		PPAR
	GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.		PPAR
T26986	Cevoglitazar	LBM-642,LBM 642,LBM642	PPAR
	Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.		PPAR
T1298	Clofibrate	Clofibrato,Clofibratum,Ethyl clofibrate	PPAR
	Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.		PPAR
T28501	Ragaglitazar	NNC61-0029,NN-622,(-)-DRF-2725,NNC-61-0029,NN 622,NNC 61-0029	PPAR
	Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglitazar can be used to study type 2 diabetes.		PPAR
T68000L	MK-0533		PPAR
	MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.		PPAR
T67855	ISX-3		Others
	ISX-3 is a potent pro-osteogenic and anti-adipogenic agent. ISX-3 can increase the expression of PPARγ. ISX-3 can be for the research of osteopenia and osteoporosis.		Others
T0841	Bezafibrate	BM15075	PPAR
	Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW-DENSITY LIPOPROTEINS and increases HIGH-DENSITY LIPOPROTEINS.		PPAR

Compounds

PPARγ/GR modulator 1

T75009

Synonym:

Target:

PPARγ phosphorylation inhibitor 1

Synonym: EPI001,EPI 001

Target: Apoptosis, Androgen Receptor, PPAR

Pioglitazone

T0214

Synonym: U 72107

Target: Ferroptosis, PPAR

Rosiglitazone

T0334

Synonym: BRL49653

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

AMG131

T8780

Synonym: INT-131,AMG-131,CHS 131

Target: PPAR

Rosiglitazone hydrochloride

T6646

Synonym: BRL-49653 HCl,Rosiglitazone HCl

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

Synonym: TIMTEC-BB SBB006523,GW 9662

Target: PPAR

MSDC-0602K

T38715

Synonym: MSDC-0602K,Azemiglitazone potassium

Target: PPAR

Troglitazone

T3170

Synonym: CS-045,Romozin,Rezulin,Romglizone,Noscal,Prelay

Target: Apoptosis, Ferroptosis, PPAR, Autophagy

Synonym: RO0728804,R1439

Saroglitazar Magnesium

Synonym: RTA-403,CDDO-Imidazolide,TP-235

Target: Others, Ferroptosis, Nrf2, PPAR

Synonym: RS5444,Efatutazone,CS-7017

Target: PPAR

Pioglitazone hydrochloride

T0214L

Synonym: U-72107E,AD 4833,U 72107A,Pioglitazone HCl

Target: Ferroptosis, PPAR

Ciglitazone

T19710

Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Target: Apoptosis, p38 MAPK, PPAR

MCC-555

T21764

Synonym: Isaglitazone,Netoglitazone

Target: PPAR

SR 16832

T24827

Synonym: SR-16832,SR16832

Synonym: LBM-642,LBM 642,LBM642

Target: PPAR

Clofibrate

T1298

Synonym: Clofibrato,Clofibratum,Ethyl clofibrate

Target: PPAR

Ragaglitazar

T28501

Synonym: NNC61-0029,NN-622,(-)-DRF-2725,NNC-61-0029,NN 622,NNC 61-0029

Cat No.	Product Name	Synonyms	Targets
TN7060	Methyl oleanonate		PPAR
	3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.		PPAR
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T6917	Oleuropein		Apoptosis , Aromatase , ROS , PPAR
	Oleuropein is an antioxidant polyphenol isolated from olive leaf.		Apoptosis , Aromatase , ROS , PPAR
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
TN1475	Caulophyllogenin	Segetalic acid	IL Receptor , TNF , PPAR , Immunology/Inflammation related
	Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the...		IL Receptor , TNF , PPAR , Immunology/Inflammation related
T3917	Protopanaxatriol	20(R)-APPT,20(R)-Protopanaxatriol,(20R)-Protopanaxatriol	PPAR
	Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist.		PPAR
T5S0788	Oroxin A	Baicalein 7-O-glucoside	PPAR
	Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.		PPAR
TN5137	Tetramethylkaempferol		transporter , PPAR
	Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempfero...		transporter , PPAR
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
T37974	(S)-Coriolic acid	13(S)-HODE	Lipoxygenase , Mitochondrial Metabolism , PPAR
	(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent, generated by the reaction of linoleic acid with plant and mammalian lipoxygenases, and is involved in cell proliferation and differentiation i...		Lipoxygenase , Mitochondrial Metabolism , PPAR
T5764	Alliin	(S)-3-(Allylsulphinyl)-L-alanine	NF-κB , PPAR
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS...		NF-κB , PPAR
T4S1545	Licarin B	(-)-Licarin B,Licarine B	transporter , Antibacterial , PPAR
	1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.		transporter , Antibacterial , PPAR
T5S1550	Cinnamyl alcohol	Cinnamic Alcohol,Styryl Carbinol	PPAR
	Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.		PPAR
TN2232	Soyasaponin Ab		NOS , NF-κB , COX
	Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.		NOS , NF-κB , COX
T7443	4'-Methoxychalcone		PARP , PPAR
	4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.		PARP , PPAR
TN1525	Convallatoxin		NF-κB , P-gp , PPAR
	Convallatoxin is a natural product		NF-κB , P-gp , PPAR
T0646	5-Aminosalicylic Acid	Mesalazine,5-ASA,Mesalamine	NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
	5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
T3403	Glabridin	Q-100692,KB-289522,LS-176045	Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
	Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T22473	15-deoxy-Δ-12,14-Prostaglandin J2		Others
	PPARγ agonist		Others
T10327	Ankaflavin		PPAR
	Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induces cell death on cancer cells.		PPAR
TN2535	1-Hydroxy-2-oxopomolic acid		transporter , PPAR , Fatty Acid Synthase
	1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα expression.		transporter , PPAR , Fatty Acid Synthase
TWS0787	Oroxin A	Baicalin-7-glucoside	PPAR , Glucosidase
	Oroxin A (Baicalin-7-glucoside) is a partial PPARγ agonist that can activate PPARγ transcriptional activation in vitro and in vivo. Oroxin A also exhibited inhibitory activity against α-glucosidase and antioxidant capaci...		PPAR , Glucosidase
T75690	Wistin
	Wistin, isolated from Caragana sinica roots, is a PPARα and PPARγ agonist [1] [2] .
T3056	Bavachinin	Bavachinin A,7-O-Methylbavachin	PPAR
	Bavachinin (Bavachinin A)(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic activity.		PPAR
TN2228	Soyasaponin Aa		PPAR
	Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factor...		PPAR
T81898	Lyciumamide A
	DPP-IV-IN-5, derived from Lycium barbarum fruits, demonstrates moderate agonistic activity towards peroxisome proliferator-activated receptor (PPARγ), showing EC50 values between 10.09 and 44.26 μM, and exhibits inhibito...
T10153	4-O-Methyl honokiol		Others
	4-O-Methyl honokiol, a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist and inhibits NF-κB activity, used for cancer and inflammation research.		Others
TMA0127	Ficusin A		transporter , PPAR
	Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPAR...		transporter , PPAR
TN4390	Kihadanin B		Akt , PPAR , FOXO1
	Kihadanin B can repress the adipogenesis by decreasing lipid accumulation through the suppression of the Akt-FOXO1-PPARγ axis in 3T3-L1 adipocytes.		Akt , PPAR , FOXO1
T72961	Falcarindiol	法卡林二醇
	Falcarindiol, an orally active polyacetylenic oxylipin, not only activates PPARγ, enhancing ABCA1 expression—a cholesterol transporter—but also induces apoptosis and autophagy. This compound exhibits anti-inflammatory, a...
T79949	Foenumoside B		PPAR
	Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes lipolysis, shifting lipid metabolism. This compound is utilized...		PPAR
TN5149	Tirotundin		NF-κB , COX , PPAR
	Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activation of NF-kappa B, thereby, the synthesis of inflammatory me...		NF-κB , COX , PPAR
TN5091	Tagitinin A		PPAR , Antifection
	Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the growth of STS and weeds. Tagitinin A is also a PPARα/γ dual ...		PPAR , Antifection
TN3366	Ailanthoidol		IL Receptor , NOS , COX , Prostaglandin Receptor , PPAR
	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potential as a chemopreventive agent against tumor promotion. Ailan...		IL Receptor , NOS , COX , Prostaglandin Receptor , PPAR
TN5369	Dehydroleucodine	Dehydroleucodin
	Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating a...
T75611	Tibesaikosaponin V
	Tibesaikosaponin V (TKV), a triterpene diglycoside isolated from the methanol extract of Bupleurum chinense DC roots, effectively inhibits lipid accumulation and triacylglycerol content in adipocytes without inducing cyt...
T83915	Norbixin hydrate
	Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ...

Natural Products

Target: Tyrosinase, Antibacterial, AMPK

Oleuropein

T6917

Synonym:

Target: Apoptosis, Aromatase, ROS, PPAR

Agrimol B

T4S1173

Synonym:

Target: Sirtuin, PPAR

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Caulophyllogenin

TN1475

Synonym: Segetalic acid

Target: IL Receptor, TNF, PPAR, Immunology/Inflammation related

Protopanaxatriol

T3917

Synonym: 20(R)-APPT,20(R)-Protopanaxatriol,(20R)-Protopanaxatriol

Target: PPAR

Oroxin A

T5S0788

Synonym: Baicalein 7-O-glucoside

Target: PPAR

Tetramethylkaempferol

TN5137

Synonym:

Target: transporter, PPAR

Isosilybin A

TN1804

Synonym:

Target: Apoptosis, Tyrosinase, PPAR, ABC

Norathyriol

TN1990

Synonym:

Target: Akt, DNA/RNA Synthesis, AMPK, PPAR

(S)-Coriolic acid

T37974

Synonym: 13(S)-HODE

Target: Lipoxygenase, Mitochondrial Metabolism, PPAR

Alliin

T5764

Synonym: (S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, PPAR

Licarin B

T4S1545

Synonym: (-)-Licarin B,Licarine B

Target: transporter, Antibacterial, PPAR

Cinnamyl alcohol

T5S1550

Synonym: Cinnamic Alcohol,Styryl Carbinol

Target: NOS, NF-κB, COX

Target: NF-κB, P-gp, PPAR

5-Aminosalicylic Acid

T0646

Synonym: Mesalazine,5-ASA,Mesalamine

Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Endogenous Metabolite, PAK, PPAR

Glabridin

T3403

Synonym: Q-100692,KB-289522,LS-176045

Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR

15-deoxy-Δ-12,14-Prostaglandin J2

1-Hydroxy-2-oxopomolic acid

TN2535

Synonym:

Target: transporter, PPAR, Fatty Acid Synthase

Oroxin A

TWS0787

Synonym: Baicalin-7-glucoside

Target: PPAR, Glucosidase

Synonym: Bavachinin A,7-O-Methylbavachin

Target: transporter, PPAR

Kihadanin B

TN4390

Synonym:

Target: Akt, PPAR, FOXO1

Target: NF-κB, COX, PPAR

Tagitinin A

TN5091

Synonym:

Target: PPAR, Antifection

Ailanthoidol

TN3366

Synonym:

Target: IL Receptor, NOS, COX, Prostaglandin Receptor, PPAR

Dehydroleucodine

TN5369

Synonym: Dehydroleucodin

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus-Insect Cells